Brief Information of the Compound and Protein
Compound Name
6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-4-(4-methylpyrimidin-5-yl)-2-piperazin-1-ylbenzimidazole
    Show/Hide
PubChem ID
CID: 145971431
Canonical SMILES
Cc1cc(Cn2c(nc3c(cc(Cl)cc23)-c2cncnc2C)N2CCNCC2)cc(C)c1F
    Show/Hide
Compound Formula C25H26ClFN6
Compound Structure
Protein Name
Son of sevenless homolog 1
Protein Classification
Unclassified protein
Uniprot ID
Q07889
Gene Name
SOS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 10200 nM
   TI
   LI
   LO
   TS
CL000654 NCI-H727 Homo sapiens (Human)  1
1
EC50 = 14500 nM
   TI
   LI
   LO
   TS