Brief Information of the Compound and Protein
Compound Name
5-[6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-1-[(4-fluorophenyl)methyl]benzimidazol-4-yl]-4-methylpyrimidin-2-amine
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PubChem ID
CID: 145964755
Canonical SMILES
Cc1nc(N)ncc1-c1cc(Cl)cc2n(Cc3ccc(F)cc3)c(nc12)N1CC2(CNC2)C1
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Compound Formula C24H23ClFN7
Compound Structure
Protein Name
Son of sevenless homolog 1
Protein Classification
Unclassified protein
Uniprot ID
Q07889
Gene Name
SOS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 14000 nM
   TI
   LI
   LO
   TS
CL000654 NCI-H727 Homo sapiens (Human)  1
1
EC50 = 27500 nM
   TI
   LI
   LO
   TS