Brief Information of the Compound and Protein
Compound Name
5-[6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]benzimidazol-4-yl]-4-methylpyrimidin-2-amine
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PubChem ID
CID: 145964923
Canonical SMILES
Cc1cc(Cn2c(nc3c(cc(Cl)cc23)-c2cnc(N)nc2C)N2CC3(CNC3)C2)cc(C)c1F
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Compound Formula C26H27ClFN7
Compound Structure
Protein Name
Son of sevenless homolog 1
Protein Classification
Unclassified protein
Uniprot ID
Q07889
Gene Name
SOS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 7800 nM
   TI
   LI
   LO
   TS
CL000654 NCI-H727 Homo sapiens (Human)  1
1
EC50 = 13400 nM
   TI
   LI
   LO
   TS