| Compound ID |
Compound Name |
Compound Formula |
|
CP0086294
|
4-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]pyridine-2-carboxamide
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|
C24H23F3N4O3S
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 < 30 nM
|
|
|
|
CP0548539
|
3-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzamide
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|
C25H24F3N3O3S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0416488
|
4-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzamide
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|
C25H24F3N3O3S
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
IC50 = 41 nM
|
|
|
|
CP0416487
|
5-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]pyridine-2-carboxamide
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|
C24H23F3N4O3S
|
2
|
| 1 |
IC50 = 17 nM
|
|
|
| 2 |
IC50 = 42 nM
|
|
|
|
CP0457807
|
4-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzonitrile
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|
C25H22F3N3O2S
|
2
|
| 1 |
IC50 = 17 nM
|
|
|
| 2 |
IC50 = 36 nM
|
|
|
|
CP0467749
|
N-[4-(4-pyridin-4-ylphenyl)sulfonylcyclohexyl]-5-(trifluoromethyl)pyridin-2-amine
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|
C23H22F3N3O2S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0396565
|
5-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]pyridine-2-carbonitrile
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|
C24H21F3N4O2S
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0557858
|
3-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzonitrile
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|
C25H22F3N3O2S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0457805
|
2-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzonitrile
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|
C25H22F3N3O2S
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0457808
|
CHEMBL4248488
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|
C23H22F3N3O2S
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0416489
|
N-[4-(4-phenylphenyl)sulfonylcyclohexyl]-5-(trifluoromethyl)pyridin-2-amine
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|
C24H23F3N2O2S
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0459162
|
6-[[4-[4-(4-tert-butylphenyl)phenyl]sulfonylcyclohexyl]amino]pyridine-3-carbonitrile
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|
C28H31N3O2S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0396566
|
N-[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]-5-(trifluoromethyl)pyridin-2-amine
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|
C23H22F3N3O2S
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0575443
|
6-[[4-(4-phenylphenyl)sulfonylcyclohexyl]amino]pyridine-3-carbonitrile
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|
C24H23N3O2S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0548541
|
6-[[1-(4-tert-butylphenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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|
C21H26N4O2S
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0416486
|
6-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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|
C23H22N4O2S
|
2
|
| 1 |
IC50 = 240 nM
|
|
|
| 2 |
IC50 = 290 nM
|
|
|
|
CP0459161
|
N-[4-(4-pyridin-2-ylphenyl)sulfonylcyclohexyl]-5-(trifluoromethyl)pyridin-2-amine
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|
C23H22F3N3O2S
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0396567
|
6-[[1-[4-(trifluoromethyl)phenyl]sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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|
C18H17F3N4O2S
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0547023
|
2-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzamide
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|
C25H24F3N3O3S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0555776
|
N-[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]-5-(trifluoromethyl)pyridin-2-amine
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|
C18H20F3N3O3S
|
1
|
| 1 |
IC50 = 940 nM
|
|
|
|
CP0396564
|
6-[[1-(4-methylphenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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|
C18H20N4O2S
|
2
|
| 1 |
IC50 = 1400 nM
|
|
|
| 2 |
IC50 = 3100 nM
|
|
|
|
CP0459164
|
6-[[1-(4-chlorophenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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|
C17H17ClN4O2S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0390906
|
4-[[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]amino]benzonitrile
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|
C19H21N3O3S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0459153
|
6-[[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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|
C18H20N4O3S
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0527212
|
6-[[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]amino]pyridine-2-carbonitrile
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|
C18H20N4O3S
|
1
|
| 1 |
IC50 = 7400 nM
|
|
|
|
CP0462137
|
1-(4-methoxyphenyl)sulfonyl-N-phenylpiperidin-4-amine
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|
C18H22N2O3S
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0572720
|
6-[[1-[4-(4-cyanophenyl)phenyl]sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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|
C24H21N5O2S
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0557855
|
6-[[1-(4-methoxyphenyl)sulfonylazepan-4-yl]amino]pyridine-3-carbonitrile
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|
C19H22N4O3S
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0557856
|
N-[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]-5-methylpyridin-2-amine
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|
C18H23N3O3S
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0390909
|
6-[[1-(4-hydroxyphenyl)sulfonylpyrrolidin-3-yl]amino]pyridine-3-carbonitrile
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|
C16H16N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0390910
|
2-[[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]amino]pyridine-4-carbonitrile
Show/Hide
|
C18H20N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0457810
|
N-[4-[4-[4-[(5-cyanopyridin-2-yl)amino]piperidin-1-yl]sulfonylphenyl]phenyl]acetamide
Show/Hide
|
C25H25N5O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0459163
|
6-[[1-[4-(3-phenylphenyl)phenyl]sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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|
C29H26N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0555777
|
6-[[4-[4-(4-tert-butylphenyl)phenyl]sulfonylcyclohexyl]amino]pyridine-3-carbonitrile
Show/Hide
|
C28H31N3O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0557857
|
N-(4-methoxyphenyl)-1-(4-methoxyphenyl)sulfonylpiperidin-4-amine
Show/Hide
|
C19H24N2O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0575449
|
6-[[1-[4-(3-methylphenyl)phenyl]sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
Show/Hide
|
C24H24N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
