General Information of the Compound
Compound ID
CP0390906
Compound Name
4-[[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]amino]benzonitrile
    Show/Hide
Structure
Formula
C19H21N3O3S
Molecular Weight
371.462
Canonical SMILES
COc1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ccc(cc1)C#N
    Show/Hide
InChI
InChI=1S/C19H21N3O3S/c1-25-18-6-8-19(9-7-18)26(23,24)22-12-10-17(11-13-22)21-16-4-2-15(14-20)3-5-16/h2-9,17,21H,10-13H2,1H3
    Show/Hide
InChIKey
ZCYUKGJJWXCCHL-UHFFFAOYSA-N
Physicochemical Property
logP
2.83208
Rotatable Bonds
5
Heavy Atom Count
26
Polar Areas
82.43
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 145984433
ChEMBL ID
CHEMBL4238408
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03815, C-C chemokine receptor type 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS