General Information of the Compound
Compound ID
CP0459162
Compound Name
CHEMBL4240463
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Formula
C28H31N3O2S
Molecular Weight
473.642
Canonical SMILES
CC(C)(C)c1ccc(cc1)-c1ccc(cc1)S(=O)(=O)[C@H]1CC[C@@H](CC1)Nc1ccc(cn1)C#N
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InChI
InChI=1S/C28H31N3O2S/c1-28(2,3)23-9-5-21(6-10-23)22-7-13-25(14-8-22)34(32,33)26-15-11-24(12-16-26)31-27-17-4-20(18-29)19-30-27/h4-10,13-14,17,19,24,26H,11-12,15-16H2,1-3H3,(H,30,31)/t24-,26-
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InChIKey
UJSQRECQWIGYBN-YOCNBXQISA-N
Physicochemical Property
logP
6.11478
Rotatable Bonds
5
Heavy Atom Count
34
Polar Areas
82.85
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4240463
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03815, C-C chemokine receptor type 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 140 nM
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