| Compound ID |
Compound Name |
Compound Formula |
|
CP0484656
|
(2S)-1-[2,4-dichloro-3-[(2-methyl-4-pyridin-3-ylquinolin-8-yl)oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
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|
C28H26Cl2N4O4S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
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CP0537636
|
8-[[2,6-dichloro-3-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylphenyl]methoxy]-2-methyl-4-(trifluoromethyl)quinoline
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|
C24H23Cl2F3N2O4S
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
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CP0484657
|
(2S)-1-[2,4-dichloro-3-[[4-imidazol-1-yl-2-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
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|
C26H22Cl2F3N5O4S
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
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CP0484662
|
(2S)-1-[2,4-dichloro-3-[[2-propan-2-yl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
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|
C26H26Cl2F3N3O4S
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0258288
|
(2S)-1-[2,4-dichloro-3-[[4-(3-methylimidazol-4-yl)-2-propan-2-ylquinolin-8-yl]oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
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|
C29H31Cl2N5O4S
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
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CP0487437
|
(2R,6S)-4-[2,4-dichloro-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-2,6-dimethylmorpholine
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|
C24H23Cl2F3N2O4S
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
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CP0537638
|
(2S)-1-[2,4-dichloro-3-[(2-propan-2-yl-4-pyridin-4-ylquinolin-8-yl)oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
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|
C30H30Cl2N4O4S
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0539165
|
(2S)-1-[2,4-dichloro-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
Show/Hide
|
C24H22Cl2F3N3O4S
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0537633
|
(2S)-1-[2,4-dichloro-3-[(2-methyl-4-phenylquinolin-8-yl)oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
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|
C29H27Cl2N3O4S
|
1
|
| 1 |
EC50 = 320 nM
|
|
|
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CP0484658
|
(2S)-1-[2,4-dichloro-3-[[2-ethyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
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|
C25H24Cl2F3N3O4S
|
1
|
| 1 |
EC50 = 350 nM
|
|
|
|
CP0549732
|
2-[1-[2,4-dichloro-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonylpiperidin-4-yl]ethanol
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|
C25H25Cl2F3N2O4S
|
1
|
| 1 |
EC50 = 390 nM
|
|
|
|
CP0487447
|
(2S)-1-[2,4-dichloro-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonylpyrrolidine-2-carboxamide
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|
C23H20Cl2F3N3O4S
|
1
|
| 1 |
EC50 = 440 nM
|
|
|
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CP0487445
|
(2S)-1-[2,4-dichloro-3-[(4-imidazol-1-yl-2-propan-2-ylquinolin-8-yl)oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
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|
C28H29Cl2N5O4S
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
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CP0539868
|
(2S)-1-[2,4-dichloro-3-[(2-methyl-4-pyridin-4-ylquinolin-8-yl)oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
Show/Hide
|
C28H26Cl2N4O4S
|
1
|
| 1 |
EC50 = 630 nM
|
|
|
|
CP0487449
|
1-[2,4-dichloro-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonylpiperidine-4-carbonitrile
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|
C24H20Cl2F3N3O3S
|
1
|
| 1 |
EC50 = 760 nM
|
|
|
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CP0487446
|
8-[(2,6-dichloro-3-pyrrolidin-1-ylsulfonylphenyl)methoxy]-2-methyl-4-(trifluoromethyl)quinoline
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|
C22H19Cl2F3N2O3S
|
1
|
| 1 |
EC50 = 810 nM
|
|
|
|
CP0537639
|
(2S)-1-[2,4-dichloro-3-[(2-methyl-4-phenylmethoxyquinolin-8-yl)oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
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|
C30H29Cl2N3O5S
|
1
|
| 1 |
EC50 = 880 nM
|
|
|
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CP0484661
|
8-[(2,6-dichloro-3-piperidin-1-ylsulfonylphenyl)methoxy]-2-methyl-4-(trifluoromethyl)quinoline
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|
C23H21Cl2F3N2O3S
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
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CP0484660
|
(3R)-1-[2,4-dichloro-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-N,N-dimethylpyrrolidin-3-amine
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|
C24H24Cl2F3N3O3S
|
1
|
| 1 |
EC50 = 910 nM
|
|
|
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CP0537635
|
(2S)-1-[2,4-dichloro-3-[(4-phenylmethoxy-2-propan-2-ylquinolin-8-yl)oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
Show/Hide
|
C32H33Cl2N3O5S
|
1
|
| 1 |
EC50 = 940 nM
|
|
|
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CP0487448
|
[(2S)-1-[2,4-dichloro-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonylpyrrolidin-2-yl]methanol
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|
C23H21Cl2F3N2O4S
|
1
|
| 1 |
EC50 = 960 nM
|
|
|
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CP0186266
|
N-ethyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
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|
C17H15F6NO3S
|
1
|
| 1 |
EC50 = 1080 nM
|
|
|
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CP0487450
|
(2S)-1-[2,4-dichloro-3-[(4-imidazol-1-yl-2-methylquinolin-8-yl)oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
Show/Hide
|
C26H25Cl2N5O4S
|
1
|
| 1 |
EC50 = 1360 nM
|
|
|
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CP0543607
|
(2S)-1-[2,4-dichloro-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonylpyrrolidine-2-carboxylic acid
Show/Hide
|
C23H19Cl2F3N2O5S
|
1
|
| 1 |
EC50 = 1390 nM
|
|
|
|
CP0537634
|
(2S)-1-[2,4-dichloro-3-[[2-methyl-4-(3-methylimidazol-4-yl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
Show/Hide
|
C27H27Cl2N5O4S
|
1
|
| 1 |
EC50 = 1510 nM
|
|
|
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CP0537637
|
(2S)-1-[2,4-dichloro-3-[(2-methyl-4-pyridin-2-ylquinolin-8-yl)oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
Show/Hide
|
C28H26Cl2N4O4S
|
1
|
| 1 |
EC50 = 1660 nM
|
|
|
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CP0484659
|
(2S)-N-methyl-1-[3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonylpyrrolidine-2-carboxamide
Show/Hide
|
C24H24F3N3O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0484663
|
(2S)-1-[2,4-dichloro-3-[[2-methyl-4-(1-methylimidazol-2-yl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-N-methylpyrrolidine-2-carboxamide
Show/Hide
|
C27H27Cl2N5O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
