Brief Information of the Compound and Protein
Compound Name
8-[(2,6-dichloro-3-piperidin-1-ylsulfonylphenyl)methoxy]-2-methyl-4-(trifluoromethyl)quinoline
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Canonical SMILES
Cc1cc(c2cccc(OCc3c(Cl)ccc(c3Cl)S(=O)(=O)N3CCCCC3)c2n1)C(F)(F)F
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Compound Formula C23H21Cl2F3N2O3S
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 900 nM
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