Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-[[2,6-dichloro-3-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonylphenyl]methoxy]-2-methyl-4-(trifluoromethyl)quinoline
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Canonical SMILES
COC[C@@H]1CCCN1S(=O)(=O)c1ccc(Cl)c(COc2cccc3c(cc(C)nc23)C(F)(F)F)c1Cl
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Compound Formula C24H23Cl2F3N2O4S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 160 nM
   TI
   LI
   LO
   TS