Brief Information of the Compound and Protein
Compound Name
(2S)-N-methyl-1-[3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonylpyrrolidine-2-carboxamide
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Canonical SMILES
CNC(=O)[C@@H]1CCCN1S(=O)(=O)c1cccc(COc2cccc3c(cc(C)nc23)C(F)(F)F)c1
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Compound Formula C24H24F3N3O4S
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS