Compound ID |
Compound Name |
Compound Formula |
CP0382183
|
(R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-diphenylacetamido)-5-oxopentylamino)(amino)methylene)ureido)acetate
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C32H38N6O6
|
10
|
1 |
IC50 = 0.05012 nM
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|
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2 |
IC50 = 0.0631 nM
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|
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3 |
IC50 = 0.1259 nM
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|
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4 |
IC50 = 0.1698 nM
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5 |
IC50 = 0.4266 nM
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6 |
IC50 = 0.7079 nM
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7 |
IC50 = 2.754 nM
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8 |
IC50 = 8.24 nM
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9 |
Ki = 0.12 nM
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10 |
Ki = 0.3 nM
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CP0562221
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(2R)-5-[[amino-[2-[(2-fluoroacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C34H39F4N7O7
|
1
|
1 |
IC50 = 0.05495 nM
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|
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CP0551789
|
(2R)-5-[[amino-[2-[(2-bromoacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C34H39BrF3N7O7
|
1
|
1 |
IC50 = 0.06166 nM
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|
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CP0567542
|
(2R)-5-[[amino-[2-(2-methylpropanoylamino)ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C36H44F3N7O7
|
1
|
1 |
IC50 = 0.06607 nM
|
|
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CP0553601
|
(2R)-5-[[amino-[2-[(2-chloroacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C34H39ClF3N7O7
|
1
|
1 |
IC50 = 0.07943 nM
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|
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CP0560329
|
(2R)-5-[[amino-[2-[(2-hydroxyacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C34H40F3N7O8
|
1
|
1 |
IC50 = 0.0912 nM
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|
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CP0181598
|
(R)-1-((5-(4-hydroxybenzylamino)-4-(2,2-diphenylacetamido)-5-oxopentylamino)(amino)methylene)-3-ethylurea
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|
C30H36N6O4
|
7
|
1 |
IC50 = 0.1 nM
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|
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2 |
IC50 = 0.1202 nM
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|
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3 |
IC50 = 0.2399 nM
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4 |
IC50 = 0.4786 nM
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5 |
IC50 = 1.23 nM
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6 |
IC50 = 8 nM
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7 |
Ki = 0.24 nM
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CP0403846
|
ethyl 3-[[N'-[(4R)-4-[(2,2-diphenylacetyl)amino]-5-[(4-hydroxyphenyl)methylamino]-5-oxopentyl]carbamimidoyl]carbamoylamino]propanoate
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|
C33H40N6O6
|
8
|
1 |
IC50 = 0.1 nM
|
|
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2 |
IC50 = 0.1047 nM
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3 |
IC50 = 0.1514 nM
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4 |
IC50 = 0.1622 nM
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5 |
IC50 = 0.3311 nM
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|
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6 |
IC50 = 0.5129 nM
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7 |
IC50 = 1.445 nM
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8 |
Ki = 0.3 nM
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CP0382200
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(2R)-5-[[amino-[2-(propanoylamino)ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C37H43F6N7O9
|
8
|
1 |
IC50 = 0.1 nM
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2 |
IC50 = 0.1288 nM
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3 |
IC50 = 0.1698 nM
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4 |
IC50 = 0.4169 nM
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5 |
IC50 = 0.871 nM
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6 |
IC50 = 2.399 nM
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7 |
IC50 = 7.61 nM
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8 |
Ki = 0.1 nM
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CP0551784
|
(2R)-5-[[amino-[2-[(2,2-difluoroacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C34H38F5N7O7
|
1
|
1 |
IC50 = 0.1096 nM
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|
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CP0565084
|
(2R)-5-[[amino-[2-[(2,2,2-trifluoroacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C34H37F6N7O7
|
1
|
1 |
IC50 = 0.1259 nM
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|
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CP0552786
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(2R)-5-[[amino-[2-(prop-2-enoylamino)ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C35H40F3N7O7
|
1
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1 |
IC50 = 0.1862 nM
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CP0385636
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(2R)-5-[[amino-[(1-methyltriazol-4-yl)methylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C34H38F3N9O6
|
6
|
1 |
IC50 = 0.195 nM
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2 |
IC50 = 0.2188 nM
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3 |
IC50 = 0.3467 nM
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|
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4 |
IC50 = 0.871 nM
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|
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5 |
IC50 = 1.698 nM
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|
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6 |
IC50 = 4.266 nM
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CP0553604
|
N-[2-[[N'-[(4R)-4-[(2,2-diphenylacetyl)amino]-5-[(4-hydroxyphenyl)methylamino]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethyl]cyclopropanecarboxamide;2,2,2-trifluoroacetic acid
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|
C36H42F3N7O7
|
1
|
1 |
IC50 = 0.2399 nM
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|
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CP0553605
|
N-[2-[[N'-[(4R)-4-[(2,2-diphenylacetyl)amino]-5-[(4-hydroxyphenyl)methylamino]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethyl]cyclobutanecarboxamide;2,2,2-trifluoroacetic acid
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|
C37H44F3N7O7
|
1
|
1 |
IC50 = 0.2399 nM
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|
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CP0553607
|
(2R)-5-[[amino-[2-[(2-aminoacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C34H41F3N8O7
|
1
|
1 |
IC50 = 0.2818 nM
|
|
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CP0553603
|
(2R)-5-[[amino-[2-(3-bromopropanoylamino)ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C35H41BrF3N7O7
|
1
|
1 |
IC50 = 0.4074 nM
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|
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CP0511921
|
(2R)-5-[[amino-[2-(3-chloropropanoylamino)ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C35H41ClF3N7O7
|
1
|
1 |
IC50 = 0.5888 nM
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CP0551788
|
N-[2-[[N'-[(4R)-4-[(2,2-diphenylacetyl)amino]-5-[(4-hydroxyphenyl)methylamino]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethyl]cyclopentanecarboxamide;2,2,2-trifluoroacetic acid
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|
C38H46F3N7O7
|
1
|
1 |
IC50 = 7.586 nM
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|
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CP0084655
|
(R)-2-(2,2-diphenylacetamido)-5-guanidino-N-(4-hydroxybenzyl)pentanamide
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|
C27H31N5O3
|
4
|
1 |
IC50 = 10.23 nM
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|
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2 |
IC50 = 11.75 nM
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3 |
IC50 = 16.22 nM
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4 |
Ki = 1.5 nM
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CP0551785
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N-[2-[[N'-[(4R)-4-[(2,2-diphenylacetyl)amino]-5-[(4-hydroxyphenyl)methylamino]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethyl]benzamide;2,2,2-trifluoroacetic acid
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|
C39H42F3N7O7
|
1
|
1 |
IC50 = 11.48 nM
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|
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CP0551787
|
(2R)-5-[[amino-[2-(2,2-dimethylpropanoylamino)ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C37H46F3N7O7
|
1
|
1 |
IC50 = 14.45 nM
|
|
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CP0551786
|
N-[2-[[N'-[(4R)-4-[(2,2-diphenylacetyl)amino]-5-[(4-hydroxyphenyl)methylamino]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethyl]-4-fluorobenzamide;2,2,2-trifluoroacetic acid
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|
C39H41F4N7O7
|
1
|
1 |
IC50 = 16.22 nM
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CP0155302
|
BIBP3226
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|
C27H31N5O3
|
1
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1 |
IC50 = 17 nM
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CP0551790
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N-[2-[[N'-[(4R)-4-[(2,2-diphenylacetyl)amino]-5-[(4-hydroxyphenyl)methylamino]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethyl]cyclohexanecarboxamide;2,2,2-trifluoroacetic acid
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|
C39H48F3N7O7
|
1
|
1 |
IC50 = 30.9 nM
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CP0458887
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid [1-(4-hydroxy-phenyl)-ethyl]-amide
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|
C28H33N5O3
|
1
|
1 |
IC50 = 60 nM
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|
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CP0403975
|
2-[2-(4-Chloro-phenyl)-2-phenyl-acetylamino]-5-guanidino-pentanoic acid benzylamide
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|
C27H30ClN5O2
|
1
|
1 |
IC50 = 81 nM
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CP0551791
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(2R)-5-[[amino-[2-[(2-phenylacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C40H44F3N7O7
|
1
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1 |
IC50 = 95.5 nM
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CP0489006
|
2-[2,2-Bis-(4-chloro-phenyl)-acetylamino]-5-guanidino-pentanoic acid benzylamide
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|
C27H29Cl2N5O2
|
1
|
1 |
IC50 = 100 nM
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|
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CP0510580
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid benzylamide
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|
C27H31N5O2
|
1
|
1 |
IC50 = 110 nM
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CP0894056
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2-Diphenylacetylamino-5-guanidino-pentanoic acid ((R)-1-phenyl-ethyl)-amide
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|
C28H33N5O2
|
1
|
1 |
IC50 = 200 nM
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CP0403793
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N-[5-(diaminomethylideneamino)-1-(7-hydroxy-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-1-oxopentan-2-yl]-2,2-diphenylacetamide
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|
C30H35N5O3
|
1
|
1 |
IC50 = 280 nM
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|
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CP0562222
|
(2R)-5-[[amino-[2-[(2-cyclohexylacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C40H50F3N7O7
|
1
|
1 |
IC50 = 457.09 nM
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CP0551792
|
(2R)-5-[[amino-[2-[(2,2-diphenylacetyl)amino]ethylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid
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|
C46H48F3N7O7
|
1
|
1 |
IC50 = 524.81 nM
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|
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CP0377492
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid ((S)-2-hydroxy-1-phenyl-ethyl)-amide
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|
C28H33N5O3
|
1
|
1 |
IC50 = 900 nM
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|
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CP0451294
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid (5-hydroxy-indan-1-yl)-amide
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|
C29H33N5O3
|
1
|
1 |
IC50 = 1000 nM
|
|
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CP0500473
|
2-(4-Chloro-phenyl)-N-[4-guanidino-1-(1,3,4,5-tetrahydro-benzo[c]azepine-2-carbonyl)-butyl]-2-phenyl-acetamide
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|
C30H34ClN5O2
|
1
|
1 |
IC50 = 1100 nM
|
|
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CP0458948
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid (S)-indan-1-ylamide
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|
C29H33N5O2
|
1
|
1 |
IC50 = 1400 nM
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|
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CP0537601
|
N-[5-(diaminomethylideneamino)-1-oxo-1-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)pentan-2-yl]-2,2-diphenylacetamide
Show/Hide
|
C30H35N5O2
|
1
|
1 |
IC50 = 2200 nM
|
|
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CP0847362
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid ((S)-1-phenyl-ethyl)-amide
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|
C28H33N5O2
|
1
|
1 |
IC50 = 2500 nM
|
|
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CP0377257
|
2-[2-(4-Chloro-phenyl)-2-phenyl-acetylamino]-5-guanidino-pentanoic acid (S)-indan-1-ylamide
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|
C29H32ClN5O2
|
1
|
1 |
IC50 = 3000 nM
|
|
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CP0440697
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid (pyridin-2-ylmethyl)-amide
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|
C26H30N6O2
|
1
|
1 |
IC50 = 3750 nM
|
|
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CP0397276
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid ((R)-carbamoyl-phenyl-methyl)-amide
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|
C28H32N6O3
|
1
|
1 |
IC50 = 4600 nM
|
|
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CP0404642
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid ((S)-carbamoyl-phenyl-methyl)-amide
Show/Hide
|
C28H32N6O3
|
1
|
1 |
IC50 = 7500 nM
|
|
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CP0501350
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid [(R)-carbamoyl-(4-hydroxy-phenyl)-methyl]-amide
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|
C28H32N6O4
|
1
|
1 |
IC50 = 8100 nM
|
|
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CP0507443
|
2-[2,2-Bis-(4-chloro-phenyl)-acetylamino]-5-guanidino-pentanoic acid (S)-indan-1-ylamide
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|
C29H31Cl2N5O2
|
1
|
1 |
IC50 > 10000 nM
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|
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CP0439620
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid (2-pyridin-2-yl-ethyl)-amide
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|
C27H32N6O2
|
1
|
1 |
IC50 = 11500 nM
|
|
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CP0397504
|
2-Biphenyl-4-yl-N-{1-(7-hydroxy-1,3,4,5-tetrahydro-benzo[c]azepine-2-carbonyl)-4-[N'-(3-phenyl-propyl)-guanidino]-butyl}-acetamide
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|
C39H45N5O3
|
1
|
1 |
IC50 = 11900 nM
|
|
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CP0397577
|
2,2-Bis-(4-chloro-phenyl)-N-[4-guanidino-1-(1,3,4,5-tetrahydro-benzo[c]azepine-2-carbonyl)-butyl]-acetamide
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|
C30H33Cl2N5O2
|
1
|
1 |
IC50 = 12000 nM
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|
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CP0510733
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid (R)-indan-1-ylamide
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|
C29H33N5O2
|
1
|
1 |
IC50 = 21000 nM
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|
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CP0461119
|
2-(2-Biphenyl-4-yl-acetylamino)-5-guanidino-pentanoic acid benzylamide
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|
C27H31N5O2
|
1
|
1 |
IC50 = 21800 nM
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|
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CP0461121
|
2-Diphenylacetylamino-5-guanidino-pentanoic acid ((R)-2-hydroxy-1-phenyl-ethyl)-amide
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|
C28H33N5O3
|
1
|
1 |
IC50 = 22300 nM
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|
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CP0536933
|
N-[5-(diaminomethylideneamino)-1-oxo-1-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)pentan-2-yl]-2,2,2-triphenylacetamide
Show/Hide
|
C36H39N5O2
|
1
|
1 |
IC50 = 51000 nM
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|
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CP0410726
|
2-Biphenyl-4-yl-N-[4-guanidino-1-(1,3,4,5-tetrahydro-benzo[c]azepine-2-carbonyl)-butyl]-acetamide
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|
C30H35N5O2
|
1
|
1 |
IC50 = 76000 nM
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|
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CP0055951
|
(4S)-5-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S,3S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-4-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid
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|
C189H285N55O57S
|
1
|
1 |
Ki = 0.5 nM
|
|
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CP0382185
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(4S)-5-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S,3R)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2R)-1-[[(2R)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[2-[[(2S)-1-[(2S)-4-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoic acid
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C190H287N55O57
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1
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1 |
Ki = 0.6 nM
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CP0375180
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]butanediamide
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C75H124N26O17
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1
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1 |
Ki = 281 nM
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CP0334304
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(4S)-5-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(1S)-1-amino-2-(4-hydroxyphenyl)ethyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-4-carboxybutanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid
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C184H287N53O53S2
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1
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1 |
Ki = 440 nM
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CP0375159
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(2S)-2-[[(2S)-2-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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C33H56N12O8
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1
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1 |
Ki > 1000 nM
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CP0375160
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(1S,2R)-2-[[(2S)-1-[[(1S,2R)-2-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]cyclobutyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]cyclobutyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide
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C76H120N28O16
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1
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1 |
Ki > 1000 nM
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CP0375161
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S,3S)-1-[[(1S,2R)-2-[[(2S)-1-[[(1S,2R)-2-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]cyclopentyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]cyclopentyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide
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C78H123N25O16
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1
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1 |
Ki > 1000 nM
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CP0375162
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(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
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C75H120N26O18
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1
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1 |
Ki > 1000 nM
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CP0375179
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(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-N-[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(1S,2R)-2-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]cyclobutyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide
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C73H119N27O18
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1
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1 |
Ki > 1000 nM
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CP0386806
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S,3S)-1-[[(1R,3S)-3-[[(2S)-1-[[(1R,3S)-3-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-2,2-dimethylcyclobutyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-2,2-dimethylcyclobutyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide
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C80H127N25O16
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1
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1 |
Ki > 1000 nM
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CP0386808
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S,3S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide
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C76H123N25O17
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1
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1 |
Ki > 1000 nM
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CP0386811
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(1R,2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]cyclopentane-1-carboxamide
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C38H56N12O8
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1
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1 |
Ki > 1000 nM
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CP0395195
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(1R,2S)-2-[[(2S)-2-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]cyclopentane-1-carboxamide
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C33H54N12O8
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1
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1 |
Ki > 1000 nM
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CP0420154
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(1S,2R)-2-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]cyclopentyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]butanediamide
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C76H126N26O17
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1
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1 |
Ki > 1000 nM
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CP0420318
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(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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C38H58N12O8
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1
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1 |
Ki > 1000 nM
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CP0429059
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S,3S)-1-[[(2S,3R)-1-[[(2S)-1-[[(1S,3R)-3-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]-2,2-dimethylcyclobutyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide
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C77H123N25O17
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1
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1 |
Ki > 1000 nM
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CP0434504
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S,3S)-1-[[(2S,3R)-1-[[(2S)-1-[[(1S,2R)-2-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]cyclopentyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide
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C76H121N25O17
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1
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1 |
Ki > 1000 nM
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CP0469093
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(1S,2R)-2-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]cyclobutyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]butanediamide
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C75H124N26O17
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1
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1 |
Ki > 1000 nM
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CP0476460
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(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S,3S)-1-[[(2S,3R)-1-[[(2S)-1-[[(1S,2R)-2-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]cyclobutyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide
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C75H119N25O17
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1
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1 |
Ki > 1000 nM
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