Brief Information of the Compound and Protein
Compound Name
ethyl 3-[[N'-[(4R)-4-[(2,2-diphenylacetyl)amino]-5-[(4-hydroxyphenyl)methylamino]-5-oxopentyl]carbamimidoyl]carbamoylamino]propanoate
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PubChem ID
CID: 127041306
Canonical SMILES
CCOC(=O)CCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1
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Compound Formula C33H40N6O6
Compound Structure
Protein Name
Neuropeptide Y receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide Y receptor
Uniprot ID
P25929
Gene Name
NPY1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL Homo sapiens (Human)  8
1
IC50 = 0.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.1047 nM
   TI
   LI
   LO
   TS
3
IC50 = 0.1514 nM
   TI
   LI
   LO
   TS
4
IC50 = 0.1622 nM
   TI
   LI
   LO
   TS
5
IC50 = 0.3311 nM
   TI
   LI
   LO
   TS
6
IC50 = 0.5129 nM
   TI
   LI
   LO
   TS
7
IC50 = 1.445 nM
   TI
   LI
   LO
   TS
8
Ki = 0.3 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 0.49 nM
   TI
   LI
   LO
   TS