Brief Information of the Cell Line and Protein
Cell Line ID: CL000276 , PA-1
Synonyms
PA1
PA I
PAI
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0479
Protein ID: PT01771 , E3 ubiquitin-protein ligase Mdm2
Gene Name MDM2
Organism Homo sapiens, Human
Protein Classification Other nuclear protein
Uniprot ID Q00987
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000276  Protein ID: PT01771
 
Compound ID Compound Name Compound Formula
CP0778805
(3S,4S)-3-(6-chloro-1H-indol-3-yl)-2-(4-chlorobenzyl)-N-(2-(4-methylpiperazin-1-yl)ethyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
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C32H33Cl2N5O2
 1
1
IC50 = 11500 nM
   TI
   LI
   LO
   TS
CP0676966
1-(4-chlorobenzyl)-5-(4-chlorophenyl)-3-hydroxy-4-phenyl-1H-pyrrol-2(5H)-one
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C23H17Cl2NO2
 1
1
IC50 = 26200 nM
   TI
   LI
   LO
   TS
CP0041876
(4S,5R)-Nutlin-3
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C30H30Cl2N4O4
 1
1
IC50 > 60000 nM
   TI
   LI
   LO
   TS
CP0778804
(3S,4S)-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid
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C23H17Cl2NO3
 1
1
IC50 > 60000 nM
   TI
   LI
   LO
   TS
CP0709749
(3S,4S)-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-N-(2-methoxyethyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
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C26H24Cl2N2O3
 1
1
IC50 = 62500 nM
   TI
   LI
   LO
   TS