Brief Information of the Cell Line and Protein
Cell Line ID: CL000752 , PBMC iPSC #1
 Cell Line Info 
Category Induced pluripotent stem cell
Organism
Homo sapiens (Human)
Protein ID: PT01540 , Non-receptor tyrosine-protein kinase TYK2
 Protein Info 
Gene Name TYK2
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P29597
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000752
 Cell Line Info 
 Protein ID: PT01540
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0014588
 Compound Info 
US10196390, Compound I-136
   Show/Hide
C21H17F2N5O2
  1
1
IC50 = 47 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0562828
 Compound Info 
US10196390, Compound I-147
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C23H21F2N5O2
  1
1
IC50 = 82 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528258
 Compound Info 
US10196390, Compound I-182
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C23H19F4N5O
  1
1
IC50 = 83 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0011836
 Compound Info 
US10196390, Compound I-231
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C24H20F2N4O3
  1
1
IC50 = 89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0543383
 Compound Info 
US10196390, Compound I-248
   Show/Hide
C22H17F2N5O3
  1
1
IC50 = 89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0261054
 Compound Info 
US10196390, Compound I-171
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C22H19F2N5O2
  1
1
IC50 = 98 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0014097
 Compound Info 
US10336752, Compound 1
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C24H20F2N4O2
  1
1
IC50 = 110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0357732
 Compound Info 
US10196390, Compound I-88
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C22H19F2N5O2
  1
1
IC50 = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578973
 Compound Info 
US10968236, Compound I-14
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C23H21F2N5O3
  1
1
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0543382
 Compound Info 
US10196390, Compound I-80
   Show/Hide
C22H19F2N5O2
  1
1
IC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS