Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10196390, Compound I-136
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 PubChem ID
CID: 118341355
Canonical SMILES
CCNC(=O)c1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)nc1
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Compound Formula C21H17F2N5O2
Compound Structure
Protein Name
 Protein Info 
Non-receptor tyrosine-protein kinase TYK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P29597
Gene Name
TYK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 47 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.15 nM