Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10196390, Compound I-248
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 PubChem ID
CID: 118341405
Canonical SMILES
Fc1cccc(F)c1-c1cc(Nc2ccc(cn2)N2CCOCC2=O)c2C(=O)NCc2n1
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Compound Formula C22H17F2N5O3
Compound Structure
Protein Name
 Protein Info 
Non-receptor tyrosine-protein kinase TYK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P29597
Gene Name
TYK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 89 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.34 nM