(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide

(R)-1-(3-(3-(3-(2-bromophenyl)-2-cyanoguanidino)-6-chloro-2-hydroxyphenylsulfonamido)pentan-3-yl)pyrrolidine-2-carboxylic acid

3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-6-chloro-2-hydroxy-N,N-dimethylbenzenesulfonamide

3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N-dimethyl-6-(trifluoromethyl)benzenesulfonamide

3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-4-methyl-3-{[3-(morpholin-4-yl)pentan-3-yl]sulfamoyl}phenyl)guanidine

3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N,6-trimethylbenzenesulfonamide

1-(3-{[3-(4-aminopiperidin-1-yl)pentan-3-yl]sulfamoyl}-4-chloro-2-hydroxyphenyl)-3-(2-bromophenyl)-2-cyanoguanidine

3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-6-fluoro-2-hydroxy-N,N-dimethylbenzenesulfonamide

3-(2-bromophenyl)-1-[4-chloro-3-({3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pentan-3-yl}sulfamoyl)-2-hydroxyphenyl]-2-cyanoguanidine

3-[2-(benzyloxy)phenyl]-1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyanoguanidine

6-chloro-3-({(cyanoimino)[(2-methylphenyl)amino]methyl}amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide

6-chloro-3-[((cyanoimino){[2-(trifluoromethyl)phenyl]amino}methyl)amino]-2-hydroxy-N,N-dimethylbenzenesulfonamide

6-chloro-3-({(cyanoimino)[(2-ethylphenyl)amino]methyl}amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide

3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-3-{[3-(morpholin-4-yl)pentan-3-yl]sulfamoyl}phenyl)guanidine

1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyano-3-(2-phenylphenyl)guanidine

1-[4-chloro-3-({3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pentan-3-yl}sulfamoyl)-2-hydroxyphenyl]-2-cyano-3-(2-methylphenyl)guanidine

3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-benzenesulfonamide

6-chloro-3-({(cyanoimino)[(2-fluorophenyl)amino]methyl}amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide

3-(2-bromo-phenylamino)-7-nitro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol

3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-N,N-dimethyl-benzenesulfonamide

3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-benzamide

6-chloro-3-{[[(3-chloro-2-fluorophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N-dimethylbenzenesulfonamide

1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyano-3-[2-(propan-2-yl)phenyl]guanidine

7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol

3-(2-chloro-phenylamino)-7-nitro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol

7-chloro-3-(2-chloro-3-fluoro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol

3-(2-bromo-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol

1-(2-Bromo-phenyl)-3-(3,4-dichloro-2-hydroxy-phenyl)-urea

7-chloro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol

7-chloro-3-(2-chloro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol

1-(3-Aminomethyl-4-chloro-2-hydroxy-phenyl)-3-(2-bromo-phenyl)-urea hydrochloride

1-(2-Bromo-phenyl)-3-(4-chloro-2-hydroxy-phenyl)-urea

N-(4-chloro-2-hydroxy-3-{[(3-exo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]sulfonyl}phenyl)-N'-(3-fluoro-2-methylphenyl)urea

N-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(3-fluoro-2-methylphenyl)urea

N-{4-chloro-2-hydroxy-3-[3-pyrrolidinylmethyl)sulfonyl]-phenyl}-N'-{2-[(trifluoromethyl)oxy]phenyl}-urea

N-{3-[(1R,5S)-8-azabicyclo[3.2.1]oct-3-yisulfonyl]-4-chloro-2-hydroxyphenyl}-N'-(3-fluoro-2-methylphenyl)urea

N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}urea

N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl-)phenyl]-N'-(2-chloro-3-pyridinyl)urea

N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3R)-pyrrolidinylsulfonyl]-phenyl}urea

N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-(3-fluoro-2-methylphenyl)urea

N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(2,2-difluoro-1,3-benzodioxol-4-yl)urea

N-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2-chloro-3-pyridinyl)urea

Ethyl 4-({6-chloro-2-hydroxy-3-[({[2-(phenylox-y)phenyl]amino}carbonyl)amino]phenyl}sulfonyl)-1-piperidinecarboxylate

N-{4-chloro-2-hydroxy-3-[(3R)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2-ethylphenyl)urea

N-(2-chloro-3-fluorophenyl)-N'-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl)urea

N-{3-[(1R,5S)-8-azabicyclo[3.2.1]oct-3-ylsulfonyl]-4-chloro-2-hydroxyphenyl}-N'-(2-chloro-3-pyridinyl)urea

N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-{2-[(trifluoromethyl)oxy]-phenyljurea

N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(2-ethylphenyl)urea

ethyl4-{[6-chloro-3-({[(3-fluoro-2-methylphenyl)amino]-carbonyljamino]-2-hydroxyphenyl[sulfonyl}-1-piperidinecarboxylate

N-{3-[(1R,5S)-8-azabicyclo[3.2.1]oct-3-yl]sulfonyl]-4-chloro-2-hydroxyphenyl}-N'-[2-(phenyloxy)phenyl)urea

N-{4-chloro-2-hydroxy-3-[(3R)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2,2-difluoro-1,3-benzodioxol-4-yl)urea

N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(3-fluoro-2-methylphenyl)urea

N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(2-chloro-3-pyridinyl)urea

N-{3-[(lR,5S)-8-azabicyclo[3.2.1]oct-3-yl]sulfonyl]-4-chloro-2-hydroxyphenyl}-N'-(2-chloro-3-fluorophenyl)urea

N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-{2-[(tritluoromethyl)oxyj-phenyl)urea

N-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}-N'-(2-chloro-3-pyridinyl)urea

N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-(2,3-dichlorophenyl)urea

N-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl}-N'-[2-(phenyloxy)phenyl]urea

N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfo-nyl)phenyl]-N'-[2-(phenyloxy)phenyl]urea

DANIRIXIN

N-[3-(3-azetidinylsulfonyl)-4-chloro-2-hydroxyphenyl]-N'-(2-chloro-3-pyridinyl)urea

N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-(2-ethylphenyl)urea

N-{4-chloro-2-hydroxy-3-[(3R)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2-(trifluoromethyl)oxy]-phenyl)urea

N-{4-chloro-2-hydroxy-3-[(3-pyrrolidinylmethyl)-sulfonyl]phenyl}-N'-(3-fluoro-2-methylphenyl)urea

N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl)urea

N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3-pyrrolidinylmethyl)-sulfonyl]phenyl}urea

ethyl4-{[6-chloro-3-({[(2-chloro-3-fluorophenyl)amino]-carbonyljamino]-2-hydroxyphenyl[sulfonyl}-1-piperidinecarboxylate

N-[3-(3-azetidinylsulfonyl)-4-chloro-2-hydroxyphenyl]-N'-(3-fluoro-3-methylphenyl)urea

N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl)urea

N-[3-(3-azetidinylsulfonyl)-4-chloro-2-hydroxyphenyl]-N'-(2-chloro-3-fluorophenyl)urea

(R)-3-(2-(1-(4-ethylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

3-(2-((R)-1-(4-sec-butylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide

(R)-3-(2-(cyclopropyl(4-isopropylfuran-2-yl)methylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

(R)-3-(2-(1-(4-tert-butylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)-2-methylpropylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-(4-morpholinobutyl)furan-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide

(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)-2,2-dimethylpropylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide

(S)-3-(3,4-dioxo-2-(2,2,2-trifluoro-1-(4-isopropylfuran-2-yl)ethylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide

(R)-3-(3,4-dioxo-2-(1-(4-(pentan-3-yl)furan-2-yl)propylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

(R)-3-(2-(1-(4-butylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)ethylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide

(R)-3-(2-(1-(4-cyclopentylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(3-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide

(R)-3-(2-(1-(4-cyclohexylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

(R)-3-(2-(1-(3-ethylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide