| Compound ID |
Compound Name |
Compound Formula |
|
CP0167569
|
4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quinoline
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|
C18H14N4
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0272495
|
4-[3-(6-Bromo-pyridin-2-yl)-1H-pyrazol-4-yl]-quinoline
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|
C17H11BrN4
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0461161
|
1-methyl-6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1Hbenzoimidazole
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|
C19H17N5
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0208736
|
6-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1Hbenzoimidazole
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|
C19H17N5
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0106785
|
4-[5-Methyl-3-(6-methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quinoline
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|
C19H16N4
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0198179
|
1-methyl-6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo-[1,2-b]pyrazol-3-yl]-1H-benzoimidazole
Show/Hide
|
C20H19N5
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0015520
|
4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline
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|
C17H12N4
|
2
|
| 1 |
IC50 = 40 nM
|
|
|
| 2 |
IC50 = 47 nM
|
|
|
|
CP0134205
|
4-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenol
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|
C15H13N3O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0101110
|
2-[4-(4-Methoxy-phenyl)-1-methyl-1H-pyrazol-3-yl]-6-methyl-pyridine
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|
C17H17N3O
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0343570
|
6-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1-(3-piperidin-1-yl-propyl)-1H-benzoimidazole
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|
C27H32N6
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0153367
|
N,N-dimethyl-3-[6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzimidazol-1-yl]propan-1-amine
Show/Hide
|
C24H28N6
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0140650
|
3-(6-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzo[d]imidazol-1-yl)propan-1-ol
Show/Hide
|
C22H23N5O
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0198178
|
3-[6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-benzoimidazol-1-yl]-propan-1-ol
Show/Hide
|
C21H21N5O
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0057017
|
4-(5-Cyclopropyl-3-pyridin-2-yl-1H-pyrazol-4-yl)-quinoline
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|
C20H16N4
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0104102
|
4-(3-(5-fluoropyridin-2-yl)-1H-pyrazol-4-yl)quinoline
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|
C17H11FN4
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0208734
|
N,N-diethyl-3-[6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzimidazol-1-yl]propan-1-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0324264
|
N,N-dimethyl-3-[6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzimidazol-1-yl]propan-1-amine
Show/Hide
|
C23H26N6
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0339842
|
6-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1-(3-pyrrolidin-1-yl-propyl)-1H-benzoimidazole
Show/Hide
|
C26H30N6
|
1
|
| 1 |
IC50 = 117 nM
|
|
|
|
CP0210175
|
2-[4-(4-Fluoro-phenyl)-1H-pyrazol-3-yl]-6-methyl-pyridine
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|
C15H12FN3
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0299325
|
4-(3-(6-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzo[d]imidazol-1-yl)propyl)morpholine
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
IC50 = 186 nM
|
|
|
|
CP0208733
|
6-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1-(3-(pyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole
Show/Hide
|
C25H28N6
|
1
|
| 1 |
IC50 = 226 nM
|
|
|
|
CP0251357
|
4-(3-(3-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)quinoline
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|
C19H12F3N3
|
1
|
| 1 |
IC50 = 355 nM
|
|
|
|
CP0234168
|
4-(1-Benzyl-3-pyridin-2-yl-1H-pyrazol-4-yl)-quinoline
Show/Hide
|
C24H18N4
|
1
|
| 1 |
IC50 = 399 nM
|
|
|
|
CP0134782
|
5-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzo[d]imidazole
Show/Hide
|
C18H15N5
|
1
|
| 1 |
IC50 = 422 nM
|
|
|
|
CP0111297
|
2-[4-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-6-methyl-pyridine
Show/Hide
|
C15H12ClN3
|
1
|
| 1 |
IC50 = 551 nM
|
|
|
|
CP0460033
|
US8772297, Y244
Show/Hide
|
C29H38N4O7S2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0355960
|
4-(4-(pyridin-2-yl)-1H-pyrazol-3-yl)quinoline
Show/Hide
|
C17H12N4
|
1
|
| 1 |
IC50 = 683 nM
|
|
|
|
CP0544674
|
US8772297, Y241
Show/Hide
|
C23H30N6O6S2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0043942
|
2-[4-(3,4-Difluoro-phenyl)-1H-pyrazol-3-yl]-6-methyl-pyridine
Show/Hide
|
C15H11F2N3
|
1
|
| 1 |
IC50 = 788 nM
|
|
|
|
CP0206051
|
4-(3-Phenyl-1H-pyrazol-4-yl)-quinoline
Show/Hide
|
C18H13N3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0132093
|
1-methyl-5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzoimidazole
Show/Hide
|
C19H17N5
|
1
|
| 1 |
IC50 = 1373 nM
|
|
|
|
CP0551317
|
US8772297, Y260
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|
C32H47N5O8S2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0197939
|
4-(3-(thiophen-2-yl)-1H-pyrazol-4-yl)quinoline
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|
C16H11N3S
|
1
|
| 1 |
IC50 = 1660 nM
|
|
|
|
CP0535606
|
US8772297, Y177
Show/Hide
|
C27H39N3O6S2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0399181
|
US8772297, Y224
Show/Hide
|
C28H40N4O6S2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0339841
|
5-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1-[3-(tetrahydro-pyran-2-yloxy)-propyl]-1H-benzoimidazole
Show/Hide
|
C27H31N5O2
|
1
|
| 1 |
IC50 = 2430 nM
|
|
|
|
CP0551318
|
US8772297, Y250
Show/Hide
|
C32H42N4O7S2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0098990
|
2-Methyl-6-(4-phenyl-1H-pyrazol-3-yl)-pyridine
Show/Hide
|
C15H13N3
|
1
|
| 1 |
IC50 = 3370 nM
|
|
|
|
CP0280369
|
2-[4-(4-Fluoro-phenyl)-1H-pyrazol-3-yl]-pyridine
Show/Hide
|
C14H10FN3
|
1
|
| 1 |
IC50 = 3530 nM
|
|
|
|
CP0569816
|
US8772297, Y186
Show/Hide
|
C27H40N4O6S2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0550319
|
US8772297, Y296
Show/Hide
|
C27H33N3O6S3
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0199523
|
5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1-[3-(tetrahydro-pyran-2-yloxy)-propyl]-1H-benzoimidazole
Show/Hide
|
C26H29N5O2
|
1
|
| 1 |
IC50 = 5890 nM
|
|
|
|
CP0535607
|
US8772297, Y284
Show/Hide
|
C27H33N3O7S2
|
1
|
| 1 |
IC50 = 6700 nM
|
|
|
|
CP0548816
|
US8772297, Y366
Show/Hide
|
C34H43N5O7S2
|
1
|
| 1 |
IC50 = 7300 nM
|
|
|
|
CP0450141
|
US8772297, Y145
Show/Hide
|
C24H30F3N3O6S2
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0290437
|
4-(3-(5-chloropyridin-2-yl)-1H-pyrazol-4-yl)quinoline
Show/Hide
|
C17H11ClN4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0551316
|
US8772297, Y155
Show/Hide
|
C24H33N3O6S2
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0517934
|
US8772297, Y178
Show/Hide
|
C25H36N4O6S2
|
1
|
| 1 |
IC50 = 15000 nM
|
|
|
|
CP0548819
|
US8772297, Y196
Show/Hide
|
C23H31N3O7S2
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0544696
|
US8772297, Y141
Show/Hide
|
C24H33N3O7S2
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0506896
|
US8772297, Y147
Show/Hide
|
C25H34N4O7S2
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0535605
|
US8772297, Y142
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|
C24H33N3O7S2
|
1
|
| 1 |
IC50 = 22000 nM
|
|
|
|
CP0517953
|
US8772297, Y185
Show/Hide
|
C27H38N4O7S2
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0460032
|
US8772297, Y098
Show/Hide
|
C23H31N3O6S2
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0464941
|
US8772297, Y140
Show/Hide
|
C24H33N3O7S2
|
1
|
| 1 |
IC50 = 30000 nM
|
|
|
|
CP0172112
|
2-(4-Phenyl-1H-pyrazol-3-yl)-pyridine
Show/Hide
|
C14H11N3
|
1
|
| 1 |
IC50 > 9000 nM
|
|
|
