Brief Information of the Compound and Protein
Compound Name
4-(1-Benzyl-3-pyridin-2-yl-1H-pyrazol-4-yl)-quinoline
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PubChem ID
CID: 10361281
SID: 15374524
Canonical SMILES
C(c1ccccc1)n1cc(c(n1)-c1ccccn1)-c1ccnc2ccccc12
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Compound Formula C24H18N4
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000271 Mv1Lu Neovison vison (American mink)  1
1
IC50 = 399 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 369 nM