Brief Information of the Compound and Protein
Compound Name
2-[4-(4-Methoxy-phenyl)-1-methyl-1H-pyrazol-3-yl]-6-methyl-pyridine
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PubChem ID
CID: 44351275
Canonical SMILES
COc1ccc(cc1)-c1cn(C)nc1-c1cccc(C)n1
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Compound Formula C17H17N3O
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000271 Mv1Lu Neovison vison (American mink)  1
1
IC50 = 47 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 44 nM