Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-(3,4-Difluoro-phenyl)-1H-pyrazol-3-yl]-6-methyl-pyridine
    Show/Hide
 PubChem ID
CID: 11807788
SID: 16922473
Canonical SMILES
Cc1cccc(n1)-c1n[nH]cc1-c1ccc(F)c(F)c1
    Show/Hide
Compound Formula C15H11F2N3
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000271 Mv1Lu
 Cell Line Info 
Neovison vison (American mink)  1
1
IC50 = 788 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 151 nM