| Compound ID |
Compound Name |
Compound Formula |
|
CP0500685
|
Aminofurazanyl-azabenzimidazole 6m
Show/Hide
|
C27H28N8O4
|
1
|
| 1 |
IC50 <= 1 nM
|
|
|
|
CP0500686
|
Aminofurazanyl-azabenzimidazole 6l
Show/Hide
|
C28H28N8O4
|
1
|
| 1 |
IC50 <= 1 nM
|
|
|
|
CP0500687
|
Aminofurazanyl-azabenzimidazole 6j
Show/Hide
|
C24H22N8O3
|
1
|
| 1 |
IC50 <= 1 nM
|
|
|
|
CP0503095
|
Aminofurazanyl-azabenzimidazole 6k
Show/Hide
|
C26H26N8O3
|
1
|
| 1 |
IC50 <= 1 nM
|
|
|
|
CP0559571
|
Aminofurazanyl-azabenzimidazole 6i
Show/Hide
|
C27H26N8O4
|
1
|
| 1 |
IC50 <= 1 nM
|
|
|
|
CP0130451
|
Aminofurazanyl-azabenzimidazole 6n
Show/Hide
|
C29H30N8O5
|
2
|
| 1 |
IC50 = 1.6 nM
|
|
|
| 2 |
IC50 = 1.8 nM
|
|
|
|
CP0559570
|
Aminofurazanyl-azabenzimidazole 6c
Show/Hide
|
C18H17N7O3
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0022283
|
Aminofurazanyl-azabenzimidazole 6h
Show/Hide
|
C25H24N8O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0279342
|
4-(4-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)-2-(2-methoxypyridin-4-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C25H20ClFN6O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0201256
|
4-[1-ethyl-7-(piperidin-4-ylmethoxy)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C16H21N7O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0235976
|
4-(4-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)-2-(6-methoxypyridin-3-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C25H20ClFN6O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0408424
|
Aminofurazanyl-azabenzimidazole 6g
Show/Hide
|
C23H19N7O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0253830
|
4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-yl)-N-(1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C24H17Cl2FN6O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0526912
|
4-{1-ethyl-6-methoxy-1H-imidazo[4,5-c]pyridin-2-yl}-1,2,5-oxadiazol-3-amine
Show/Hide
|
C11H12N6O2
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0285463
|
N-(1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydropyridine-3-carboxamide
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0017665
|
2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-[2-(methylamino)ethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide
Show/Hide
|
C14H18N8O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0212236
|
4-(7-{[(3R)-3-aminopyrrolidin-1-yl]carbonyl}-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
Show/Hide
|
C15H18N8O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0209348
|
4-(4-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)-2-(4-methoxyphenyl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C26H21ClFN5O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0090990
|
[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone
Show/Hide
|
C15H18N8O2
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0093074
|
4-(4-chloro-2-fluorophenyl)-N-(6-fluoro-1H-indazol-5-yl)-2-(2-methoxypyridin-4-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C25H19ClF2N6O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0224310
|
4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-yl)-N-(6-fluoro-1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C24H16Cl2F2N6O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0018621
|
N-(7-chloro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydropyridine-3-carboxamide
Show/Hide
|
C21H16ClF3N4O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0019103
|
4-(3,4-Dichlorophenyl)-N-1H-indazol-5-yl-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxamide
Show/Hide
|
C20H16Cl2N4O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0039477
|
4-[1-ethyl-7-(piperidin-4-yloxy)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C15H19N7O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0480540
|
4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-(pyridin-4-yl)-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C24H19FN6O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0022920
|
2-methyl-N-(3-methyl-1H-indazol-5-yl)-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydropyridine-3-carboxamide
Show/Hide
|
C22H19F3N4O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0027376
|
N-(1H-indazol-5-yl)-2-methyl-4-(naphthalen-2-yl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxamide
Show/Hide
|
C24H20N4O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0458568
|
4-(4-chloro-2-fluorophenyl)-N-(6-fluoro-1H-indazol-5-yl)-6-methyl-2-(2-methylpyridin-4-yl)-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C25H19ClF2N6O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0076849
|
4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
Show/Hide
|
C10H10N6O
|
2
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 19 nM
|
|
|
|
CP0293518
|
4-[7-[4-(aminomethyl)phenyl]-1-ethylimidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine;hydrochloride
Show/Hide
|
C17H18ClN7O
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0458569
|
4-(4-chloro-2-fluorophenyl)-2-(2-ethoxypyridin-4-yl)-N-(6-fluoro-1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C26H21ClF2N6O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0541372
|
1-(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)ethan-1-one
Show/Hide
|
C18H16N6O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0025658
|
GSK-180736A
Show/Hide
|
C19H16FN5O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0285462
|
N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydropyridine-3-carboxamide
Show/Hide
|
C21H16F4N4O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0461403
|
4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-yl)-6-methyl-N-(3-methyl-1H-indazol-5-yl)-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C25H19Cl2FN6O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0541723
|
4-[6-(3-aminophenoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C16H15N7O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0293912
|
3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]prop-2-yn-1-ol
Show/Hide
|
C16H19N7O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0322855
|
4-[1-ethyl-7-(piperazin-1-ylcarbonyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C15H18N8O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0522761
|
4-[2-fluoro-4-(trifluoromethyl)phenyl]-N-(1H-indazol-5-yl)-2-(4-methoxyphenyl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C27H21F4N5O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0528474
|
4-{1-ethyl-6-phenoxy-1H-imidazo[4,5-c]pyridin-2-yl}-1,2,5-oxadiazol-3-amine
Show/Hide
|
C16H14N6O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0461520
|
4-[1-ethyl-6-(3-methanesulfonylphenoxy)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C17H16N6O4S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0212235
|
2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-(piperidin-3-yl)-1H-imidazo[4,5-c]pyridine-7-carboxamide
Show/Hide
|
C16H20N8O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0485013
|
4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-2-(4-methoxyphenyl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C26H22FN5O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0291315
|
4-(4-Fluorophenyl)-N-1H-indazol-5-yl-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide
Show/Hide
|
C20H17FN4O2
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0475045
|
Dihydropyrimidine, 19
Show/Hide
|
C26H24N6O4S
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0020923
|
4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-[6-(trifluoromethyl)pyridin-3-yl]-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C25H18F4N6O
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0496772
|
Aminofurazanyl-azabenzimidazole 6d
Show/Hide
|
C18H17N7O3
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0485012
|
4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-(4-methylphenyl)-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C26H22FN5O
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0458571
|
2-(3-fluoro-4-methylphenyl)-4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C26H21F2N5O
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0163915
|
4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-phenyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C25H20FN5O
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0456127
|
4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-(pyrazin-2-yl)-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C23H18FN7O
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0257046
|
4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrrol-3-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C17H20N8O2
|
1
|
| 1 |
IC50 = 126 nM
|
|
|
|
CP0288239
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]but-3-yn-1-ol
Show/Hide
|
C17H21N7O3
|
1
|
| 1 |
IC50 = 126 nM
|
|
|
|
CP0399206
|
4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-(3-methylphenyl)-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C26H22FN5O
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0461405
|
2-(4-chlorophenyl)-4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C25H19ClFN5O
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0496064
|
Dihydropyrimidine, 17
Show/Hide
|
C27H25N5O4S
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0016240
|
(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE
Show/Hide
|
C14H21N3O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0219925
|
4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C17H20N8O2
|
1
|
| 1 |
IC50 = 158 nM
|
|
|
|
CP0496063
|
4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-(pyridin-2-yl)-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C24H19FN6O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0641015
|
GSK561866B
Show/Hide
|
C18H21F3N8O4
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0211776
|
4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrazol-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C16H19N9O2
|
1
|
| 1 |
IC50 = 224 nM
|
|
|
|
CP0257047
|
(2S)-3-[(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-4-(3-hydroxy-3-methylbut-1-yn-1-yl)-1H-imidazo[4,5-c]pyridin-7-yl]oxy}propyl)amino]propane-1,2-diol
Show/Hide
|
C21H29N7O5
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0461404
|
4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-[3-(trifluoromethyl)phenyl]-1,4-dihydropyrimidine-5-carboxamide
Show/Hide
|
C26H19F4N5O
|
1
|
| 1 |
IC50 = 288 nM
|
|
|
|
CP0015602
|
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
Show/Hide
|
C14H17N3O2S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0206212
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(2-aminoethoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C17H21N7O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0206214
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(4-aminobutoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C19H25N7O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0211684
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C18H23N7O3
|
1
|
| 1 |
IC50 = 501 nM
|
|
|
|
CP0291267
|
4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C17H19N7O3
|
1
|
| 1 |
IC50 = 562 nM
|
|
|
|
CP0163512
|
1-(1H-indazol-5-yl)-3-(2-phenylethyl)urea
Show/Hide
|
C16H16N4O
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0272431
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(pyrrolidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C20H25N7O3
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0375393
|
Dihydropyrimidine, 18
Show/Hide
|
C21H21N5O2
|
1
|
| 1 |
IC50 = 863 nM
|
|
|
|
CP0041156
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C21H27N7O3
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0640604
|
GSK619487A
Show/Hide
|
C22H26F3N7O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0163510
|
1-benzyl-3-(4-pyridin-4-ylphenyl)urea
Show/Hide
|
C19H17N3O
|
1
|
| 1 |
IC50 = 1150 nM
|
|
|
|
CP0211778
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-[(3S)-3-amino-4-phenylbutoxy]-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C25H29N7O3
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0151042
|
1-[(2R)-1-hydroxy-3-phenylpropan-2-yl]-3-(4-pyridin-4-ylphenyl)urea
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
IC50 = 1410 nM
|
|
|
|
CP0039474
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3R)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C21H27N7O3
|
1
|
| 1 |
IC50 = 1580 nM
|
|
|
|
CP0121490
|
1-[(1S)-2-hydroxy-1-phenylethyl]-3-(4-pyridin-4-ylphenyl)urea
Show/Hide
|
C20H19N3O2
|
1
|
| 1 |
IC50 = 1690 nM
|
|
|
|
CP0219924
|
4-[7-(3-aminopropoxy)-4-(2-cyclopropylethynyl)-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine
Show/Hide
|
C18H21N7O2
|
1
|
| 1 |
IC50 = 1995 nM
|
|
|
|
CP0102941
|
1-[2-(4-chlorophenyl)ethyl]-3-(1H-indazol-5-yl)urea
Show/Hide
|
C16H15ClN4O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0155307
|
1-(1H-indazol-5-yl)-3-(3-phenylpropyl)urea
Show/Hide
|
C17H18N4O
|
1
|
| 1 |
IC50 = 2460 nM
|
|
|
|
CP0110171
|
N-(4-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydropyridine-3-carboxamide
Show/Hide
|
C21H16F4N4O2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0641487
|
GSK554170A
Show/Hide
|
C23H28F3N7O5
|
1
|
| 1 |
IC50 = 2510 nM
|
|
|
|
CP0234360
|
1-(1H-indazol-5-yl)-3-[2-(4-methoxyphenyl)ethyl]urea
Show/Hide
|
C17H18N4O2
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0151043
|
1-(2-phenylethyl)-3-(4-pyridin-4-ylphenyl)urea
Show/Hide
|
C20H19N3O
|
1
|
| 1 |
IC50 = 2610 nM
|
|
|
|
CP0102940
|
1-(2-hydroxy-2-phenylethyl)-3-(1H-indazol-5-yl)urea
Show/Hide
|
C16H16N4O2
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0069884
|
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(3-{[2-(4-methoxyphenyl)ethyl]amino}propoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C27H33N7O4
|
1
|
| 1 |
IC50 = 3980 nM
|
|
|
|
CP0151041
|
1-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-3-(1H-indazol-5-yl)urea
Show/Hide
|
C17H18N4O2
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0102943
|
1-[(1R)-2-hydroxy-1-phenylethyl]-3-(4-pyridin-4-ylphenyl)urea
Show/Hide
|
C20H19N3O2
|
1
|
| 1 |
IC50 = 9070 nM
|
|
|
|
CP0147288
|
1-benzyl-3-(1H-indazol-5-yl)urea
Show/Hide
|
C15H14N4O
|
1
|
| 1 |
IC50 = 13900 nM
|
|
|
|
CP0147289
|
3-(1H-indazol-5-yl)-1-methyl-1-(2-phenylethyl)urea
Show/Hide
|
C17H18N4O
|
1
|
| 1 |
IC50 = 21500 nM
|
|
|
|
CP0147290
|
1-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-3-(4-pyridin-4-ylphenyl)urea
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
IC50 = 31010 nM
|
|
|
|
CP0311820
|
3-(1H-indazol-5-yl)-1,1-dimethylurea
Show/Hide
|
C10H12N4O
|
1
|
| 1 |
IC50 = 59100 nM
|
|
|
|
CP0138199
|
N-(1H-indazol-5-yl)acetamide
Show/Hide
|
C9H9N3O
|
1
|
| 1 |
IC50 = 65000 nM
|
|
|
|
CP0246673
|
4-chloro-N-pyridin-4-ylpyridine-3-carboxamide
Show/Hide
|
C11H8ClN3O
|
1
|
| 1 |
IC50 = 72500 nM
|
|
|
|
CP0122284
|
N-pyridin-4-ylpyridine-3-carboxamide
Show/Hide
|
C11H9N3O
|
1
|
| 1 |
IC50 = 75500 nM
|
|
|
|
CP0151044
|
1-(1H-indazol-5-yl)-3-phenylurea
Show/Hide
|
C14H12N4O
|
1
|
| 1 |
IC50 = 157100 nM
|
|
|
|
CP0128203
|
1H-Indazol-5-ylamine
Show/Hide
|
C7H7N3
|
1
|
| 1 |
IC50 = 181300 nM
|
|
|
|
CP0080483
|
5-bromo-N-pyridin-4-ylpyridine-3-carboxamide
Show/Hide
|
C11H8BrN3O
|
1
|
| 1 |
IC50 = 270000 nM
|
|
|
|
CP0163513
|
4-(4-fluorophenyl)-N-pyridin-4-ylpyridine-3-carboxamide
Show/Hide
|
C17H12FN3O
|
1
|
| 1 |
IC50 > 400000 nM
|
|
|
|
CP0330879
|
5-(4-fluorophenyl)-N-pyridin-4-ylpyridine-3-carboxamide
Show/Hide
|
C17H12FN3O
|
1
|
| 1 |
IC50 > 400000 nM
|
|
|
|
CP0382649
|
3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)-N-[2-[2-[2-[2-[[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-methylamino]ethoxy]ethoxy]ethoxy]ethyl]propanamide
Show/Hide
|
C50H56BF2N7O7
|
1
|
| 1 |
Kd = 26 nM
|
|
|
|
CP0382724
|
3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)-N-[2-[2-[2-[2-[[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]propanamide
Show/Hide
|
C49H54BF2N7O7
|
1
|
| 1 |
Kd = 35 nM
|
|
|
