Brief Information of the Compound and Protein
Compound Name
[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone
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PubChem ID
CID: 16095343
SID: 24741763
Canonical SMILES
CCn1c(nc2cncc(C(=O)N3CC[C@H](N)C3)c12)-c1nonc1N
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Compound Formula C15H18N8O2
Compound Structure
Protein Name
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 5.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM