Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-chlorophenyl)-4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
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 PubChem ID
CID: 25093239
SID: 56467851
Canonical SMILES
CC1=C(C(NC(=N1)c1ccc(Cl)cc1)c1ccc(F)cc1)C(=O)Nc1ccc2[nH]ncc2c1
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Compound Formula C25H19ClFN5O
Compound Structure
Protein Name
 Protein Info 
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 129 nM
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