Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
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 PubChem ID
CID: 3547
SID: 14849184
Canonical SMILES
O=S(=O)(N1CCCNCC1)c1cccc2cnccc12
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Compound Formula C14H17N3O2S
Compound Structure
Protein Name
 Protein Info 
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 260 nM
2 IC50 = 660 nM
3 IC50 = 940 nM
4 IC50 = 3162.28 nM
5 IC50 = 4300 nM
6 Ki = 100 nM
7 Ki = 530 nM