Brief Information of the Compound and Protein
Compound Name
(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE
    Show/Hide
PubChem ID
SID: 14847630
Canonical SMILES
C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1
    Show/Hide
Compound Formula C14H21N3O
Compound Structure
Protein Name
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 93 nM
2 IC50 = 870.96 nM
3 Ki = 25.12 nM
4 Ki = 140 nM
5 Ki = 150 nM
6 Ki = 220 nM