Brief Information of the Cell Line and Protein
Cell Line ID: CL000049 , C6
Synonyms
C-6
C 6
RGC-6
RGC6
RGc6
Category Cancer cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0194
Protein ID: PT01173 , Histamine H3 receptor
Gene Name HRH3
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID Q9QYN8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000049  Protein ID: PT01173
 
Compound ID Compound Name Compound Formula
CP0099745
4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole
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C16H18N2O2
 1
1
Ki = 0.5129 nM
   TI
   LI
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   TS
CP0105643
(4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-methanone
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C22H22FNO2
 1
1
Ki = 1 nM
   TI
   LI
   LO
   TS
CP0393298
1-(3-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-phenyl)-propan-1-one
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C24H27NO2
 1
1
Ki = 1 nM
   TI
   LI
   LO
   TS
CP0135044
(4'-(3-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)propoxy)biphenyl-4-yl)(morpholino)methanone
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C26H34N2O3
 1
1
Ki = 1.66 nM
   TI
   LI
   LO
   TS
CP0044006
(R)-2-methyl-3-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinolin-2-yl)-1,8-naphthyridine
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C25H26N4
 1
1
Ki = 1.95 nM
   TI
   LI
   LO
   TS
CP0469232
4-{2-[2-((S)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-benzonitrile
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C22H22N2O
 1
1
Ki = 2.57 nM
   TI
   LI
   LO
   TS
CP0136874
(2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-yl]butanamide
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C29H49N3O
 1
1
Ki = 2.57 nM
   TI
   LI
   LO
   TS
CP0044460
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
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C15H24N4S
 1
1
Ki = 3.631 nM
   TI
   LI
   LO
   TS
CP0093148
4-[3-(methylamino)azetidin-1-yl]spiro[6,7-dihydro-5H-quinazoline-8,1'-cyclopentane]-2-amine
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C16H25N5
 1
1
Ki = 6.761 nM
   TI
   LI
   LO
   TS
CP0472186
2,2,2-trichloroethyl N-methyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-yl]carbamate
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C26H39Cl3N2O2
 1
1
Ki = 7.91 nM
   TI
   LI
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   TS
CP0093147
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]spiro[6,7-dihydro-5H-quinazoline-8,1'-cyclopentane]-2-amine
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C17H27N5
 1
1
Ki = 72.44 nM
   TI
   LI
   LO
   TS
CP0373379
4-[(3R)-3-aminopyrrolidin-1-yl]spiro[6,7-dihydro-5H-quinazoline-8,1'-cyclopentane]-2-amine
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C16H25N5
 1
1
Ki = 79.43 nM
   TI
   LI
   LO
   TS
CP0095456
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-8-phenyl-6,7,8,9-tetrahydro-5H-cyclohepta[d]pyrimidin-2-amine
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C20H27N5
 1
1
Ki = 104.71 nM
   TI
   LI
   LO
   TS
CP0740002
SID56462982
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C8H14N4O
 1
1
Ki = 294 nM
   TI
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   TS
CP0229853
2,4-diamino-5,6-disubstituted pyrimidine, 14
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C19H25N5
 1
1
Ki = 660.69 nM
   TI
   LI
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   TS
CP0443503
(1R,2S,5S,9R,12S,13R,16S)-16-(dimethylamino)-7,13-dimethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-6-one
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C23H36N2O
 1
1
Ki = 1000 nM
   TI
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   TS