Brief Information of the Compound and Protein
Compound Name
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]spiro[6,7-dihydro-5H-quinazoline-8,1'-cyclopentane]-2-amine
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PubChem ID
CID: 44231735
SID: 85250997
Canonical SMILES
CN[C@@H]1CCN(C1)c1nc(N)nc2c1CCCC21CCCC1
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Compound Formula C17H27N5
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9QYN8
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
Ki = 72.44 nM
   TI
   LI
   LO
   TS