| Compound ID |
Compound Name |
Compound Formula |
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CP0390481
|
(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-5-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]pentanoic acid
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C78H113N21O18
|
2
|
| 1 |
EC50 = 0.01 nM
|
|
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| 2 |
IC50 = 0.01 nM
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CP0091326
|
(3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexanoylamino)-9-benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
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C50H69N15O9
|
12
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| 1 |
EC50 < 0.03162 nM
|
|
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| 2 |
EC50 = 0.3 nM
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|
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| 3 |
EC50 = 1 nM
|
|
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| 4 |
EC50 = 1.02 nM
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| 5 |
EC50 = 1.8 nM
|
|
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| 6 |
EC50 = 4.4 nM
|
|
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| 7 |
IC50 = 0.1 nM
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| 8 |
IC50 = 0.2 nM
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|
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| 9 |
IC50 = 1 nM
|
|
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| 10 |
IC50 = 1.2 nM
|
|
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| 11 |
IC50 = 1.9 nM
|
|
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| 12 |
Ki = 0.1122 nM
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CP0458133
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(S)-2-Acetamido-N-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(1H-imidazol-4-yl)propanamide
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|
C36H44N8O4
|
2
|
| 1 |
EC50 = 0.045 nM
|
|
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| 2 |
Ki = 1.3 nM
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CP0041451
|
CAS_75921-69-6
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C78H111N21O19
|
1
|
| 1 |
EC50 = 0.07 nM
|
|
|
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CP0455645
|
BREMELANOTIDE
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C50H68N14O10
|
2
|
| 1 |
EC50 = 0.0955 nM
|
|
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| 2 |
Ki = 1.905 nM
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|
|
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CP0448170
|
(S)-2-{2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-naphthalen-2-yl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C40H54N12O7
|
2
|
| 1 |
EC50 = 0.1 nM
|
|
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| 2 |
IC50 = 16 nM
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CP0374300
|
(3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(4H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C50H69N15O9
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
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CP0473015
|
(2S)-2-acetamido-N-[(2R)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-amino-1-oxo-3-sulfanylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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|
C49H70N18O9S2
|
2
|
| 1 |
EC50 = 0.263 nM
|
|
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| 2 |
Ki = 3.09 nM
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|
|
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CP0376447
|
(S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(1H-imidazol-4-yl)propanamide
Show/Hide
|
C36H44N8O4
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
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| 2 |
Ki = 0.65 nM
|
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|
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CP0462964
|
(3S,6S,9R,12S,15S,23S)-15-[(2S)-2-aminohexanamido]-6-(3-carbamimidamidopropyl)-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide
Show/Hide
|
C52H69N15O8
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
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| 2 |
IC50 = 0.2 nM
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|
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CP0383815
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(S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(4-methoxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
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C39H52N12O7
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2
|
| 1 |
EC50 = 0.4 nM
|
|
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| 2 |
IC50 = 70 nM
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CP0040024
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(3-phenyl-propionylamino)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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|
C41H49N11O5
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
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CP0408806
|
1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,41-dimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
|
C77H113N23O16S2
|
2
|
| 1 |
EC50 = 0.5248 nM
|
|
|
| 2 |
Ki = 5.754 nM
|
|
|
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CP0045108
|
(4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid
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|
C77H109N21O19S
|
4
|
| 1 |
EC50 = 0.7 nM
|
|
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| 2 |
EC50 = 0.9 nM
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|
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| 3 |
EC50 = 1.6 nM
|
|
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| 4 |
IC50 = 0.4 nM
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CP0390103
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(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]pentanoic acid
Show/Hide
|
C77H111N21O18S
|
2
|
| 1 |
EC50 = 0.7 nM
|
|
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| 2 |
IC50 = 0.4 nM
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|
|
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CP0408810
|
1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38,41-trimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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|
C78H115N23O16S2
|
2
|
| 1 |
EC50 = 0.7413 nM
|
|
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| 2 |
Ki = 1.862 nM
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CP0408822
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38,41,47-tetramethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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|
C79H117N23O16S2
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2
|
| 1 |
EC50 = 0.9333 nM
|
|
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| 2 |
Ki = 9.55 nM
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CP0409775
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(S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-naphthalen-1-yl-ethyl]-amide
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|
C36H47Cl2N11O6
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1
|
| 1 |
EC50 = 1 nM
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|
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CP0050965
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21-(2-Acetylamino-hexanoylamino)-7-[3-(diaminomethaniminium)-propyl]-10-(1H-indol-3-ylmethyl)-4-naphthalen-2-ylmethyl-2,5,8,11,19,22-hexaoxo-3,6,9,12,18,23-hexaaza-tricyclo[21.7.0.0*24,29*]triaconta-24(29),25,27
Show/Hide
|
C54H71N15O9
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2
|
| 1 |
EC50 = 1.5 nM
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| 2 |
IC50 = 1 nM
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CP0388054
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Ac-Tyr-Val-Nle-Gly-His-DPhe-Arg-Trp-Asp-Arg-Phe-Gly-NH2)
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C77H104N22O16
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2
|
| 1 |
EC50 = 1.5 nM
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| 2 |
IC50 = 0.5 nM
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CP0393265
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Ac-Tyr-Val-Nle-Gly-His-D-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2
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C77H104N22O17
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2
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| 1 |
EC50 = 1.5 nM
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| 2 |
IC50 = 0.5 nM
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CP0410091
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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|
C77H103N21O16
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2
|
| 1 |
EC50 = 1.5 nM
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| 2 |
IC50 = 0.16 nM
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CP0432640
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38-dimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
|
C77H113N23O16S2
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2
|
| 1 |
EC50 = 1.514 nM
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|
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| 2 |
Ki = 3.89 nM
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CP0047872
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(S)-2-{(S)-2-[(S)-2-[2-(4-Chloro-phenoxy)-acetylamino]-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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|
C40H46ClN11O6
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1
|
| 1 |
EC50 = 2 nM
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CP0228189
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-phenylacetylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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|
C40H47N11O5
|
1
|
| 1 |
EC50 = 2 nM
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|
|
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CP0228609
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-pentanoylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C37H49N11O5
|
1
|
| 1 |
EC50 = 2 nM
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|
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CP0393261
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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|
C80H105N19O16
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2
|
| 1 |
EC50 = 2 nM
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|
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| 2 |
IC50 = 2 nM
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CP0393262
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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|
C77H103N21O16
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2
|
| 1 |
EC50 = 2 nM
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|
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| 2 |
IC50 = 0.7 nM
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CP0870111
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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C42H47N13O8S
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2
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| 1 |
EC50 = 2 nM
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| 2 |
IC50 = 3.7 nM
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CP0388946
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
|
| 1 |
EC50 = 2.1 nM
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|
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| 2 |
IC50 = 3.9 nM
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CP0395362
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(2R,4R)-1-((R)-2-((S)-2-acetamido-3-(1H-imidazol-4-yl)propanamido)-3-phenylpropanoyl)-N-(2-guanidinoethyl)-4-(naphthalen-2-ylmethoxy)pyrrolidine-2-carboxamide
Show/Hide
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C36H43N9O5
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2
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| 1 |
EC50 = 3 nM
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| 2 |
Ki = 13 nM
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CP0393258
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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|
C79H103N21O16
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2
|
| 1 |
EC50 = 3 nM
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|
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| 2 |
IC50 = 0.3 nM
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CP0674615
|
H-Tyr-Val-Nle-Gly-His-D-Nal(2)-Arg-D-Trp-Asp-Arg-Phe-Gly-NH2
Show/Hide
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C79H104N22O15
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2
|
| 1 |
EC50 = 3 nM
|
|
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| 2 |
IC50 = 0.3 nM
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CP0389095
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(2S)-1-acetyl-N-[(2R)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-chlorophenyl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
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|
C33H41ClN6O5
|
2
|
| 1 |
EC50 = 3 nM
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|
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| 2 |
IC50 = 1.9 nM
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CP0545381
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
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C56H74N14O8S2
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2
|
| 1 |
EC50 = 3 nM
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| 2 |
IC50 = 19 nM
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CP0547334
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
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C54H70N14O8S2
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2
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| 1 |
EC50 = 3 nM
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|
|
| 2 |
IC50 = 3.5 nM
|
|
|
|
CP0182921
|
N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]cyclopropanecarboxamide
Show/Hide
|
C36H45N11O5
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0432200
|
1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25-methyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
|
C76H111N23O16S2
|
2
|
| 1 |
EC50 = 3.548 nM
|
|
|
| 2 |
Ki = 30.2 nM
|
|
|
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CP0382073
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C56H75N15O9
|
2
|
| 1 |
EC50 = 3.7 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0481186
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-[[(2S)-2-(butanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-thiophen-2-ylpropanoyl]amino]-5-(diaminomethylideneamino)pentanamide
Show/Hide
|
C36H48N12O6S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0550596
|
(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
Show/Hide
|
C54H70N14O8S2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
IC50 = 7.3 nM
|
|
|
|
CP0455642
|
1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38,47-trimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
|
C78H115N23O16S2
|
2
|
| 1 |
EC50 = 4.074 nM
|
|
|
| 2 |
Ki = 6.761 nM
|
|
|
|
CP0394004
|
(S)-2-acetamido-N1-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
Show/Hide
|
C32H41N7O4
|
2
|
| 1 |
EC50 = 4.3 nM
|
|
|
| 2 |
Ki = 103 nM
|
|
|
|
CP0045745
|
(S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C34H43N11O5
|
2
|
| 1 |
EC50 = 4.3 nM
|
|
|
| 2 |
IC50 = 105 nM
|
|
|
|
CP0049389
|
(S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C36H47N11O5
|
1
|
| 1 |
EC50 = 4.5 nM
|
|
|
|
CP0390435
|
(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C73H100N18O15
|
2
|
| 1 |
EC50 = 4.5 nM
|
|
|
| 2 |
IC50 = 24 nM
|
|
|
|
CP0390482
|
(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C74H102N20O15
|
2
|
| 1 |
EC50 = 4.6 nM
|
|
|
| 2 |
IC50 = 82 nM
|
|
|
|
CP0217814
|
(S)-2-{(S)-2-[(S)-2-(2,2-Dimethyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C37H49N11O5
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0149367
|
(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide
Show/Hide
|
C33H41ClN6O2
|
4
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
EC50 = 1400 nM
|
|
|
| 3 |
Ki = 300 nM
|
|
|
| 4 |
Ki = 1500 nM
|
|
|
|
CP0400882
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C55H73N15O9
|
2
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
IC50 = 12.6 nM
|
|
|
|
CP0408819
|
1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,41,47-trimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
|
C78H115N23O16S2
|
2
|
| 1 |
EC50 = 5.754 nM
|
|
|
| 2 |
Ki = 128.82 nM
|
|
|
|
CP0545281
|
(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
Show/Hide
|
C56H74N14O8S2
|
2
|
| 1 |
EC50 = 6.1 nM
|
|
|
| 2 |
IC50 = 44 nM
|
|
|
|
CP0204764
|
(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(3,3,3-trifluoro-propionylamino)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C35H42F3N11O5
|
1
|
| 1 |
EC50 = 6.5 nM
|
|
|
|
CP0389097
|
(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
|
C34H41ClN8O5
|
2
|
| 1 |
EC50 = 6.5 nM
|
|
|
| 2 |
IC50 = 122 nM
|
|
|
|
CP0551926
|
(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
Show/Hide
|
C56H74N14O8S2
|
2
|
| 1 |
EC50 = 6.5 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
|
CP0101637
|
N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]benzamide
Show/Hide
|
C39H45N11O5
|
1
|
| 1 |
EC50 = 6.8 nM
|
|
|
|
CP0190200
|
(S)-5-Guanidino-2-{(S)-2-[(S)-2-(2-hydroxy-acetylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C34H43N11O6
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0257564
|
N'-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]oxamide
Show/Hide
|
C34H42N12O6
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0336462
|
(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-isobutyrylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C36H47N11O5
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0089083
|
(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-propionylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C35H45N11O5
|
1
|
| 1 |
EC50 = 7.5 nM
|
|
|
|
CP0100500
|
(S)-2-{(S)-2-[(S)-2-(2-Cyano-acetylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C35H42N12O5
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0133486
|
(D)-(S)-5-Guanidino-2-{(S)-2-[(S)-2-(2-hydroxy-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C41H49N11O6
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0422298
|
(S)-2-acetamido-N-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(1H-imidazol-4-yl)propanamide
Show/Hide
|
C36H44N8O4
|
2
|
| 1 |
EC50 = 8 nM
|
|
|
| 2 |
Ki = 4.7 nM
|
|
|
|
CP0376683
|
(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C75H102N22O16
|
2
|
| 1 |
EC50 = 8 nM
|
|
|
| 2 |
IC50 = 1 nM
|
|
|
|
CP0407279
|
(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C75H102N22O15
|
2
|
| 1 |
EC50 = 8 nM
|
|
|
| 2 |
IC50 = 42 nM
|
|
|
|
CP0482142
|
(10S,13S,16S,19R,22S)-19-benzyl-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-7,12,15,18,21,24-hexaoxo-6,11,14,17,20,23-hexazaspiro[4.19]tetracosane-10-carboxamide
Show/Hide
|
C43H55N13O7
|
2
|
| 1 |
EC50 = 8.6 nM
|
|
|
| 2 |
IC50 = 93 nM
|
|
|
|
CP0049442
|
(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(2-methylsulfanyl-acetylamino)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C35H45N11O5S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0870012
|
US8846601, 150
Show/Hide
|
C49H71N17O10
|
2
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
Ki = 130 nM
|
|
|
|
CP0182484
|
(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(2-methoxy-acetylamino)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C35H45N11O6
|
1
|
| 1 |
EC50 = 9.5 nM
|
|
|
|
CP0182893
|
(S)-2-{(S)-2-[(S)-2-[2-(4-Chloro-phenyl)-acetylamino]-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C40H46ClN11O5
|
1
|
| 1 |
EC50 = 9.5 nM
|
|
|
|
CP0406326
|
(S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C38H50N12O6
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
IC50 = 575 nM
|
|
|
|
CP0430601
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-[[(2S)-2-(butanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(3,4-dichlorophenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanamide
Show/Hide
|
C38H48Cl2N12O6
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
IC50 = 250 nM
|
|
|
|
CP0421223
|
N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]piperidine-4-carboxamide
Show/Hide
|
C36H44FN5O4
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
Ki = 17 nM
|
|
|
|
CP0044562
|
(S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C38H50N12O6
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0389092
|
(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-[4-(trifluoromethyl)phenyl]propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
|
C35H41F3N8O5
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
IC50 = 339 nM
|
|
|
|
CP0389091
|
(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-bromophenyl)propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
|
C34H41BrN8O5
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
IC50 = 154 nM
|
|
|
|
CP0308897
|
(S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C34H43N11O5
|
3
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
EC50 = 14 nM
|
|
|
| 3 |
Ki = 35 nM
|
|
|
|
CP0861304
|
US8846601, 161
Show/Hide
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C48H69N17O10
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2
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| 1 |
EC50 = 13 nM
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| 2 |
Ki = 155 nM
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CP0383563
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(5S,8R,11S,14S,17S)-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
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C45H55N13O7
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2
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| 1 |
EC50 = 13 nM
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| 2 |
IC50 = 470 nM
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CP0404106
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(10S,13S,16S,19R,22S)-19-benzyl-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-8,12,15,18,21,24-hexaoxo-7,11,14,17,20,23-hexazaspiro[5.18]tetracosane-10-carboxamide
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C43H55N13O7
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2
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| 1 |
EC50 = 13 nM
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| 2 |
IC50 = 240 nM
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CP0178413
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(S)-5-Guanidino-2-{(S)-2-[(S)-2-(4-hydroxy-butyrylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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C36H47N11O6
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1
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| 1 |
EC50 = 13.7 nM
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CP0430602
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-2-[[(2R)-2-[[(2S)-2-(butanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanamide
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C40H51N11O6
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2
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| 1 |
EC50 = 14 nM
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| 2 |
IC50 = 600 nM
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CP0044734
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(S)-2-{(R)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid ((S)-1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-amide
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C37H46N10O5
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2
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| 1 |
EC50 = 14 nM
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| 2 |
Ki = 13 nM
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CP0888182
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US8846601, 155
Show/Hide
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C48H69N17O10
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2
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| 1 |
EC50 = 14 nM
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| 2 |
Ki = 240 nM
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CP0383561
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(9S,12S,15S,18R,21S)-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-18-(naphthalen-2-ylmethyl)-7,11,14,17,20,23-hexaoxo-6,10,13,16,19,22-hexazaspiro[4.18]tricosane-9-carboxamide
Show/Hide
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C46H55N13O7
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2
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| 1 |
EC50 = 14 nM
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| 2 |
IC50 = 290 nM
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CP0388945
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C54H71N15O9
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2
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| 1 |
EC50 = 14.8 nM
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| 2 |
IC50 = 8.7 nM
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CP0402649
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(5S,8R,11S,14S,17S)-8-benzyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C41H53N13O7
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2
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| 1 |
EC50 = 15 nM
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| 2 |
IC50 = 320 nM
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CP0402648
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(10S,13S,16S,19R,22S)-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-19-(naphthalen-2-ylmethyl)-8,12,15,18,21,24-hexaoxo-7,11,14,17,20,23-hexazaspiro[5.18]tetracosane-10-carboxamide
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C47H57N13O7
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2
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| 1 |
EC50 = 16 nM
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| 2 |
IC50 = 140 nM
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CP0859925
|
US8846601, 160
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C48H69N17O10
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2
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| 1 |
EC50 = 18 nM
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| 2 |
Ki = 295 nM
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CP0861303
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US8846601, 152
Show/Hide
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C49H71N17O10
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2
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| 1 |
EC50 = 18 nM
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| 2 |
Ki = 120 nM
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CP0422296
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(S)-N-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
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C38H44N6O3
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2
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| 1 |
EC50 = 19 nM
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| 2 |
Ki = 19 nM
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CP0502378
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(S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(4-chloro-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
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C38H49ClN12O6
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2
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| 1 |
EC50 = 20 nM
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| 2 |
IC50 = 300 nM
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CP0474709
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US10179804, Example 162
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C50H70N16O10
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2
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| 1 |
EC50 = 22 nM
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| 2 |
Ki = 255 nM
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CP0388943
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 23 nM
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| 2 |
IC50 = 16.7 nM
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CP0425429
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(2R,4R)-1-((R)-2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-3-phenylpropanoyl)-N-(2-guanidinoethyl)-4-(naphthalen-2-ylmethoxy)pyrrolidine-2-carboxamide
Show/Hide
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C34H41N9O4
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2
|
| 1 |
EC50 = 24 nM
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| 2 |
Ki = 15 nM
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CP0850427
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US8846601, 154::US8846601, 202
Show/Hide
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C48H69N17O10
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2
|
| 1 |
EC50 = 25 nM
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|
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| 2 |
Ki = 688 nM
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CP0404108
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(9S,12S,15S,18R,21S)-18-benzyl-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-6,11,14,17,20,23-hexaoxo-5,10,13,16,19,22-hexazaspiro[3.19]tricosane-9-carboxamide
Show/Hide
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C42H53N13O7
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2
|
| 1 |
EC50 = 25 nM
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|
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| 2 |
IC50 = 55 nM
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CP0389096
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
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C34H41FN8O5
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2
|
| 1 |
EC50 = 25 nM
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|
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| 2 |
IC50 = 243 nM
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CP0376246
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7,10,13-pentamethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C59H81N15O9
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3
|
| 1 |
EC50 = 25.7 nM
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|
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| 2 |
IC50 = 68.4 nM
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|
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| 3 |
Kd = 1.585 nM
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CP0382074
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C58H79N15O9
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2
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| 1 |
EC50 = 26 nM
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| 2 |
IC50 = 9.9 nM
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CP0377557
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(3S,6S,14S,17R,20R,23R,26S)-6-[[(2R)-2-acetamidohexanoyl]amino]-23-benzyl-20-[3-(diaminomethylideneamino)propyl]-3,17-bis(1H-indol-3-ylmethyl)-2,5,8,16,19,22,25-heptaoxo-1,4,9,15,18,21,24-heptazabicyclo[24.3.0]nonacosane-14-carboxamide
Show/Hide
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C60H79N15O10
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2
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| 1 |
EC50 = 26 nM
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| 2 |
IC50 > 5000 nM
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CP0861305
|
US8846601, 159
Show/Hide
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C49H71N17O10
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2
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| 1 |
EC50 = 26 nM
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| 2 |
Ki = 133 nM
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CP0376380
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(S)-N-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
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C34H44N6O3
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2
|
| 1 |
EC50 = 28 nM
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| 2 |
Ki = 125 nM
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CP0408790
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(9S,12S,15S,18R,21S)-18-benzyl-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-7,11,14,17,20,23-hexaoxo-6,10,13,16,19,22-hexazaspiro[4.18]tricosane-9-carboxamide
Show/Hide
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C42H53N13O7
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2
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| 1 |
EC50 = 28 nM
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| 2 |
IC50 = 440 nM
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CP0408808
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,47-dimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
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C77H113N23O16S2
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2
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| 1 |
EC50 = 29.51 nM
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| 2 |
Ki = 489.78 nM
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CP0429872
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-[[(2S)-2-(butanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-1-ylpropanoyl]amino]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C42H52N12O6
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2
|
| 1 |
EC50 = 30 nM
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| 2 |
IC50 = 4000 nM
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CP0376440
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(S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
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C34H44N6O3
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2
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| 1 |
EC50 = 30 nM
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| 2 |
Ki = 40 nM
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CP0402862
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-5-carbamimidamido-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C75H101N21O16
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2
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| 1 |
EC50 = 31 nM
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| 2 |
IC50 = 23 nM
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CP0048619
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2-{(S)-2-[(S)-2-Amino-3-(3H-imidazol-4-yl)-propionylamino]-1-oxo-3-phenyl-propylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C32H41N11O4
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1
|
| 1 |
EC50 = 31.8 nM
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CP0050698
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(S)-2-{(S)-2-[(S)-2-(4-Chloro-benzenesulfonylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C38H44ClN11O6S
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1
|
| 1 |
EC50 = 33.3 nM
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CP0376217
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
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| 1 |
EC50 = 36 nM
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| 2 |
IC50 = 175 nM
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CP0396380
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14,17-dimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
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C81H111N23O17S2
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2
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| 1 |
EC50 = 38.02 nM
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| 2 |
Ki = 218.78 nM
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CP0407277
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C73H100N20O15S
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2
|
| 1 |
EC50 = 40 nM
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| 2 |
IC50 > 1000 nM
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CP0429705
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(9S,12S,15S,18R,21S)-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-18-(naphthalen-2-ylmethyl)-6,11,14,17,20,23-hexaoxo-5,10,13,16,19,22-hexazaspiro[3.19]tricosane-9-carboxamide
Show/Hide
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C46H55N13O7
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2
|
| 1 |
EC50 = 41 nM
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| 2 |
IC50 = 120 nM
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CP0408821
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43S,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25-methyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
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C76H111N23O16S2
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2
|
| 1 |
EC50 = 41.69 nM
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| 2 |
Ki = 363.08 nM
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CP0388184
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1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-(methylamino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-2-propylpiperazin-1-yl)-1-oxopropan-2-yl)cyclopentanecarboxamide
Show/Hide
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C36H44FN5O4
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2
|
| 1 |
EC50 = 44 nM
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| 2 |
Ki = 225 nM
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CP0374873
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(S)-2-acetamido-N1-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
Show/Hide
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C35H45N7O5
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2
|
| 1 |
EC50 = 45 nM
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| 2 |
Ki = 35 nM
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CP0373660
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-[[(2S)-2-(butanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C42H52N12O6
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2
|
| 1 |
EC50 = 48 nM
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|
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| 2 |
IC50 = 5000 nM
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CP0371977
|
1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-(methylamino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-2-propylpiperazin-1-yl)-1-oxopropan-2-yl)cyclobutanecarboxamide
Show/Hide
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C35H42FN5O4
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2
|
| 1 |
EC50 = 48 nM
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|
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| 2 |
Ki = 144 nM
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CP0389079
|
(8S,11S,14S,17R,20S)-14-[3-(diaminomethylideneamino)propyl]-20-(1H-imidazol-5-ylmethyl)-11-(1H-indol-3-ylmethyl)-17-(naphthalen-2-ylmethyl)-6,10,13,16,19,22-hexaoxo-5,9,12,15,18,21-hexazaspiro[3.18]docosane-8-carboxamide
Show/Hide
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C45H53N13O7
|
2
|
| 1 |
EC50 = 48 nM
|
|
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| 2 |
IC50 = 112 nM
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CP0388186
|
(2S)-N-Methyl-2-[(3S)-4-(N-methyl-L-alanyl-4-fluoro-D-phenylalanyl)-2-oxo-3-propyl-1-piperazinyl]-3-(2-naphthalenyl)propanamide
Show/Hide
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C34H42FN5O4
|
2
|
| 1 |
EC50 = 50 nM
|
|
|
| 2 |
Ki = 101 nM
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CP0400431
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C55H73N15O9
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2
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| 1 |
EC50 = 50.8 nM
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| 2 |
IC50 = 1.4 nM
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CP0376439
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(S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide
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C33H42N6O3
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2
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| 1 |
EC50 = 52 nM
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| 2 |
Ki = 55 nM
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CP0389089
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
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C34H42N8O5
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2
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| 1 |
EC50 = 52 nM
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| 2 |
IC50 = 50 nM
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CP0383814
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(S)-2-{(S)-3-(4-Bromo-phenyl)-2-[(S)-2-butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
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C38H49BrN12O6
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2
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| 1 |
EC50 = 54 nM
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| 2 |
IC50 = 300 nM
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CP0408813
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C79H107N23O17S2
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2
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| 1 |
EC50 = 54.95 nM
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| 2 |
Ki = 281.84 nM
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CP0404788
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(S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-p-tolyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
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C39H52N12O6
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1
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| 1 |
EC50 = 55 nM
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CP0863666
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H-Tyr-Val-Nle-Gly-Pro-Phe-Arg-D-Nal(2'')-Asp-Arg-Phe-Gly-NH2
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C76H102N18O16
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2
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| 1 |
EC50 = 55 nM
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| 2 |
IC50 = 20 nM
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CP0402650
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(11S,14S,17S,20R,23S)-20-benzyl-17-[3-(diaminomethylideneamino)propyl]-23-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-8,13,16,19,22,25-hexaoxo-7,12,15,18,21,24-hexazaspiro[5.19]pentacosane-11-carboxamide
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C44H57N13O7
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2
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| 1 |
EC50 = 57 nM
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| 2 |
IC50 = 99 nM
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CP0382072
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,10,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C58H79N15O9
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2
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| 1 |
EC50 = 58 nM
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| 2 |
IC50 = 1460 nM
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CP0874171
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US8846601, 71
Show/Hide
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C49H71N17O10
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2
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| 1 |
EC50 = 60 nM
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| 2 |
Ki = 3350 nM
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CP0383564
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(8S,11S,14S,17R,20S)-17-benzyl-14-[3-(diaminomethylideneamino)propyl]-20-(1H-imidazol-5-ylmethyl)-11-(1H-indol-3-ylmethyl)-6,10,13,16,19,22-hexaoxo-5,9,12,15,18,21-hexazaspiro[3.18]docosane-8-carboxamide
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C41H51N13O7
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2
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| 1 |
EC50 = 60 nM
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| 2 |
IC50 > 1000 nM
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CP0383562
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(5S,8R,11S,14S,17S)-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,19-hexaoxo-1,4,7,10,13,16-hexazacyclononadecane-17-carboxamide
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C44H53N13O7
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2
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| 1 |
EC50 = 67 nM
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| 2 |
IC50 = 180 nM
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CP0440775
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(2S)-N-((1R)-1-[(4-Fluorophenyl)methyl]-2-{(2S)-4-[(1S)-2-(methylamino)-1-(2-naphthalenylmethyl)-2-oxoethyl]-3-oxo-2-propyl-1-piperazinyl}-2-oxoethyl)-2-piperidinecarboxamide
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C36H44FN5O4
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2
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| 1 |
EC50 = 69 nM
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| 2 |
Ki = 100 nM
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CP0407278
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C74H100N22O15S
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2
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| 1 |
EC50 = 70 nM
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| 2 |
IC50 = 1.2 nM
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CP0442493
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(S)-2-acetamido-N-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(4-hydroxyphenyl)propanamide
Show/Hide
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C39H46N6O5
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2
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| 1 |
EC50 = 71 nM
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| 2 |
Ki = 138 nM
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CP0858758
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C44H48N12O8S
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2
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| 1 |
EC50 = 71 nM
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| 2 |
IC50 = 180 nM
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CP0376382
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(S)-N-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
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C38H44N6O3
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2
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| 1 |
EC50 = 72 nM
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| 2 |
Ki = 562 nM
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CP0877954
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(cyclopentylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C44H53N11O8S
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1
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| 1 |
EC50 = 76 nM
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CP0421219
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(3S)-N-((1R)-1-[(4-Fluorophenyl)methyl]-2-{(2S)-4-[(1S)-2-(methylamino)-1-(2-naphthalenylmethyl)-2-oxoethyl]-3-oxo-2-propyl-1-piperazinyl}-2-oxoethyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
Show/Hide
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C40H44FN5O4
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2
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| 1 |
EC50 = 80 nM
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| 2 |
Ki = 194 nM
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CP0376106
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C75H101N21O16
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2
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| 1 |
EC50 = 80 nM
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| 2 |
IC50 = 60 nM
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CP0861289
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US8846601, 156
Show/Hide
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C48H69N17O10
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2
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| 1 |
EC50 = 80 nM
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| 2 |
Ki = 840 nM
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CP0432642
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14-methyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
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C80H109N23O17S2
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2
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| 1 |
EC50 = 85.11 nM
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| 2 |
Ki = 831.76 nM
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CP0404107
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(5S,8R,11S,14S,17S)-8-benzyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-3,6,9,12,15,19-hexaoxo-1,4,7,10,13,16-hexazacyclononadecane-17-carboxamide
Show/Hide
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C40H51N13O7
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2
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| 1 |
EC50 = 87 nM
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| 2 |
IC50 = 601 nM
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CP0184237
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-methanesulfonylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C33H43N11O6S
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1
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| 1 |
EC50 = 88 nM
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CP0376444
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(S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(4-hydroxyphenyl)propanamide
Show/Hide
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C39H46N6O5
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2
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| 1 |
EC50 = 88 nM
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| 2 |
Ki = 85 nM
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CP0408815
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-17-methyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
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C80H109N23O17S2
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2
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| 1 |
EC50 = 97.72 nM
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| 2 |
Ki = 338.84 nM
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CP0376441
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(S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
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C38H44N6O3
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2
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| 1 |
EC50 = 98 nM
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| 2 |
Ki = 42 nM
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CP0421224
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(S)-2-((S)-4-((R)-3-(4-Fluorophenyl)-2-(2-(methylamino)acetamido)propanoyl)-2-oxo-3-propylpiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
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C33H40FN5O4
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2
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| 1 |
EC50 = 98 nM
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| 2 |
Ki = 271 nM
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CP0870114
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(3R,6R,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C42H47N13O8S
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2
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| 1 |
EC50 = 100 nM
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| 2 |
IC50 = 1000 nM
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CP0376449
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N-[(2R)-1-[(2R,4R)-2-[2-(diaminomethylideneamino)ethylcarbamoyl]-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]piperidine-4-carboxamide
Show/Hide
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C34H43N7O4
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2
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| 1 |
EC50 = 104 nM
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| 2 |
Ki = 121 nM
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CP0442686
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
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C35H40FN5O5
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2
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| 1 |
EC50 = 104 nM
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| 2 |
Ki = 361 nM
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CP0545380
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
Show/Hide
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C54H70N14O8S2
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2
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| 1 |
EC50 = 107 nM
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| 2 |
IC50 = 275 nM
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CP0383567
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(10S,13S,16S,19R,22S)-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-19-(naphthalen-2-ylmethyl)-7,12,15,18,21,24-hexaoxo-6,11,14,17,20,23-hexazaspiro[4.19]tetracosane-10-carboxamide
Show/Hide
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C47H57N13O7
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2
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| 1 |
EC50 = 108 nM
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| 2 |
IC50 = 43 nM
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CP0506159
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(S)-2-[2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(3,4-dichloro-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C38H50N12O6
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1
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| 1 |
EC50 = 110 nM
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CP0382100
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-13-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C55H73N15O9
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2
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| 1 |
EC50 = 115 nM
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| 2 |
IC50 = 106 nM
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CP0378891
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,10,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 117 nM
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| 2 |
IC50 = 1740 nM
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CP0387976
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Ac-Tyr-Val-Nle-Gly-His-DPhe-Pro-Trp-Asp-Arg-Phe-Gly-NH2
Show/Hide
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C76H99N19O16
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2
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| 1 |
EC50 = 120 nM
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| 2 |
IC50 = 190 nM
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CP0421220
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(S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fluorophenyl)-propanoyl)-2-oxo-3-propylpiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
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C34H42FN5O4
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2
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| 1 |
EC50 = 145 nM
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| 2 |
Ki = 174 nM
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CP0373601
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(S)-2-{2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-naphthalen-1-yl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C40H51N11O6
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2
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| 1 |
EC50 = 150 nM
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| 2 |
IC50 = 1200 nM
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CP0441673
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1-(3-((2S,4R)-1-((R)-2-amino-3-phenylpropanoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-2-yl)propyl)guanidine
Show/Hide
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C28H35N5O2
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2
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| 1 |
EC50 = 151 nM
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| 2 |
Ki = 381 nM
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CP0397038
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Ac-Nle-c[Asp-His-DNaI(2')-Pro-Trp-Lys]-NH2
Show/Hide
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C53H66N12O9
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2
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| 1 |
EC50 = 160 nM
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| 2 |
IC50 = 600 nM
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CP0440776
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(2S)-N-((1R)-1-[(4-Fluorophenyl)methyl]-2-{(2S)-4-[(1S)-2-(methylamino)-1-(2-naphthalenylmethyl)-2-oxoethyl]-3-oxo-2-propyl-1-piperazinyl}-2-oxoethyl)-2-pyrrolidinecarboxamide
Show/Hide
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C35H42FN5O4
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2
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| 1 |
EC50 = 170 nM
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| 2 |
Ki = 299 nM
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CP0406035
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(S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C38H50N12O7
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1
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| 1 |
EC50 = 180 nM
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CP0421221
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]pyridine-3-carboxamide
Show/Hide
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C36H38FN5O4
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2
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| 1 |
EC50 = 193 nM
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| 2 |
Ki = 364 nM
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CP0376438
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(S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-phenylpropanamide
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C39H46N6O4
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2
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| 1 |
EC50 = 201 nM
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| 2 |
Ki = 182 nM
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CP0491908
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4-(3,5-Dipropyl-phenyl)-1-pentanoylamino-cyclohexanecarboxylic acid ((R)-1-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide
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C52H72N10O6
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1
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| 1 |
EC50 = 210 nM
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CP0376215
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,10-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 214 nM
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| 2 |
IC50 = 246 nM
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CP0866921
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-(4-fluorophenyl)propanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C40H45FN10O5
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2
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| 1 |
EC50 = 226 nM
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| 2 |
IC50 = 258 nM
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CP0442508
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N-[(2R)-1-[(2S,4R)-2-[3-(diaminomethylideneamino)propyl]-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]acetamide
Show/Hide
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C30H37N5O3
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2
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| 1 |
EC50 = 232 nM
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| 2 |
Ki = 463 nM
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CP0376209
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7,10,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C58H79N15O9
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2
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| 1 |
EC50 = 273 nM
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| 2 |
IC50 = 1380 nM
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CP0404604
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(S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(R)-2-benzo[b]thiophen-3-yl-1-(carbamoylmethyl-carbamoyl)-ethyl]-amide
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C38H49N11O6S
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2
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| 1 |
EC50 = 274 nM
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| 2 |
IC50 = 2880 nM
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CP0381782
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7,10-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 276 nM
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| 2 |
IC50 = 1330 nM
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CP0099822
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CAS_72711-43-4
Show/Hide
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C74H99N21O16S
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2
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| 1 |
EC50 = 300 nM
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| 2 |
IC50 = 1000 nM
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CP0388181
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(2S)-2-((3S)-4-{4-Fluoro-N-[(methyloxy)acetyl]-D-phenylalanyl}-2-oxo-3-propyl-1-piperazinyl)-N-methyl-3-(2-naphthalenyl)propanamide
Show/Hide
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C33H39FN4O5
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2
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| 1 |
EC50 = 308 nM
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| 2 |
Ki = 889 nM
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CP0376219
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
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| 1 |
EC50 = 315 nM
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| 2 |
IC50 = 196 nM
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CP0395396
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(S)-2-acetamido-N1-((R)-1-((2R,4R)-2-(2-guanidinoethylcarbamoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
Show/Hide
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C35H44N8O6
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2
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| 1 |
EC50 = 328 nM
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| 2 |
Ki = 893 nM
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CP0374305
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((3R,4S)-1-cyclobutyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C28H34F2N2O2
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1
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| 1 |
EC50 = 350 nM
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CP0378892
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7,10,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 366 nM
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| 2 |
IC50 = 1070 nM
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CP0396381
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-17,23-dimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
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C81H111N23O17S2
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2
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| 1 |
EC50 = 389.05 nM
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| 2 |
Ki = 1047.13 nM
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CP0374869
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(S)-N-((R)-1-((2R,4R)-2-(2-guanidinoethylcarbamoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
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C34H43N7O4
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2
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| 1 |
EC50 = 390 nM
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| 2 |
Ki = 631 nM
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CP0421225
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]pyridine-2-carboxamide
Show/Hide
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C36H38FN5O4
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2
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| 1 |
EC50 = 392 nM
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| 2 |
Ki = 637 nM
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CP0376435
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(S)-2-acetamido-N1-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
Show/Hide
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C32H41N7O4
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2
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| 1 |
EC50 = 402 nM
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| 2 |
Ki = 443 nM
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CP0432645
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14,23-dimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
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C81H111N23O17S2
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2
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| 1 |
EC50 = 416.87 nM
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| 2 |
Ki = 2344.23 nM
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CP0389093
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
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C38H44N8O5
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2
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| 1 |
EC50 = 418 nM
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| 2 |
IC50 > 1000 nM
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CP0377259
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]pyridine-4-carboxamide
Show/Hide
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C36H38FN5O4
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2
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| 1 |
EC50 = 432 nM
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| 2 |
Ki = 798 nM
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CP0376436
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(S)-N-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
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C34H44N6O3
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2
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| 1 |
EC50 = 449 nM
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| 2 |
Ki = 340 nM
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CP0495915
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(S)-2-acetamido-N1-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
Show/Hide
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C32H41N7O4
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2
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| 1 |
EC50 = 521 nM
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| 2 |
Ki = 1572 nM
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CP0452991
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(S)-N-((R)-1-((2R,4R)-2-(2-guanidinoethylcarbamoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
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C38H43N7O4
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2
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| 1 |
EC50 = 539 nM
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| 2 |
Ki = 1615 nM
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CP0400880
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,10-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
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| 1 |
EC50 = 563 nM
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| 2 |
IC50 = 3110 nM
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CP0442509
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N-[(2R)-1-[(2S,4R)-2-[3-(diaminomethylideneamino)propyl]-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide
Show/Hide
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C37H43N5O3
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2
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| 1 |
EC50 = 585 nM
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| 2 |
Ki = 611 nM
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CP0390484
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C75H101N19O15
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2
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| 1 |
EC50 = 604 nM
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| 2 |
IC50 = 137 nM
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CP0420692
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(S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(3-trifluoromethyl-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C39H49F3N12O6
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2
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| 1 |
EC50 = 611 nM
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| 2 |
IC50 = 9600 nM
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CP0372168
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Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DNal(2')-Arg-Trp-Lys]-NH2
Show/Hide
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C54H74N16O9
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2
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| 1 |
EC50 = 620 nM
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| 2 |
IC50 = 2.3 nM
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CP0383565
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(11S,14S,17S,20R,23S)-17-[3-(diaminomethylideneamino)propyl]-23-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-20-(naphthalen-2-ylmethyl)-8,13,16,19,22,25-hexaoxo-7,12,15,18,21,24-hexazaspiro[5.19]pentacosane-11-carboxamide
Show/Hide
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C48H59N13O7
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2
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| 1 |
EC50 = 631 nM
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| 2 |
IC50 = 100 nM
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CP0376211
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7,10,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C58H79N15O9
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2
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| 1 |
EC50 = 679 nM
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| 2 |
IC50 = 1810 nM
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CP0381480
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4-(3-Methoxy-phenyl)-1-pentanoylamino-cyclohexanecarboxylic acid ((R)-1-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide
Show/Hide
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C47H62N10O7
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1
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| 1 |
EC50 = 690 nM
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CP0865305
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-(4-bromophenyl)propanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C40H45BrN10O5
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2
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| 1 |
EC50 = 700 nM
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| 2 |
IC50 = 300 nM
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CP0388185
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1-Amino-N-((1R)-1-[(4-fluorophenyl)methyl]-2-{(2S)-4-[(1S)-2-(methylamino)-1-(2-naphthalenylmethyl)-2-oxoethyl]-3-oxo-2-propyl-1-piperazinyl}-2-oxoethyl)cyclopropanecarboxamide
Show/Hide
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C34H40FN5O4
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2
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| 1 |
EC50 = 734 nM
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| 2 |
Ki = 1655 nM
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CP0383468
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((3S,4R)-4-(2,4-difluorophenyl)-1-isopropylpyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C27H34F2N2O2
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1
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| 1 |
EC50 = 750 nM
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CP0848658
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(S)-2-((R)-2-((S)-7-acetamido-6-oxo-7,8-dihydro-4H-[1,2,3]triazolo[1,5-a][1,4]diazepin-5(6H)-yl)-3-phenylpropanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C34H42N12O5
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2
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| 1 |
EC50 = 750 nM
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| 2 |
IC50 = 4540 nM
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CP0376248
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7,10-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
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| 1 |
EC50 = 759 nM
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| 2 |
IC50 = 4.9 nM
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CP0372163
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Ac-Nle-c[Asp-His-DPhe-cis-4-guanidinyl-Pro-Trp-Lys]-NH2
Show/Hide
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C50H67N15O9
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1
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| 1 |
EC50 = 760 nM
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CP0481519
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]-2,2-dimethylpropanamide
Show/Hide
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C35H43FN4O4
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2
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| 1 |
EC50 = 796 nM
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| 2 |
Ki = 994 nM
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CP0870113
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(cyclohexylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C45H55N11O8S
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2
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| 1 |
EC50 = 810 nM
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| 2 |
IC50 > 2000 nM
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CP0375705
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Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-Lys]-NH2
Show/Hide
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C50H72N16O9
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2
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| 1 |
EC50 = 820 nM
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| 2 |
IC50 = 2.7 nM
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CP0911168
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2-Pentanoylamino-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid ((R)-1-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide
Show/Hide
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C44H56N10O6
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1
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| 1 |
EC50 = 830 nM
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CP0382077
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7,10-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C58H79N15O9
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2
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| 1 |
EC50 = 841 nM
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| 2 |
IC50 = 1220 nM
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CP0377556
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(3S,9S,17S,20S,23S,26R,29S)-9-[[(2S)-2-acetamidohexanoyl]amino]-26-benzyl-23-[3-(diaminomethylideneamino)propyl]-20-(1H-indol-3-ylmethyl)-2,8,11,19,22,25,28-heptaoxo-1,7,12,18,21,24,27-heptazatricyclo[27.3.0.03,7]dotriacontane-17-carboxamide
Show/Hide
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C54H76N14O10
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2
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| 1 |
EC50 = 860 nM
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| 2 |
IC50 > 5000 nM
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CP0430807
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]-1,3-thiazole-4-carboxamide
Show/Hide
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C34H36FN5O4S
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2
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| 1 |
EC50 = 878 nM
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| 2 |
Ki = 1594 nM
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CP0444827
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(2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-5-(3-carbamimidamidopropyl)-2-[(4-chlorophenyl)methyl]-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide
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C52H68ClN13O8
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2
|
| 1 |
EC50 = 900 nM
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|
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| 2 |
IC50 > 1000 nM
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CP0377559
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(3S,9S,17S,20S,23S,26R,29S)-9-[[(2S)-2-acetamidohexanoyl]amino]-23-[3-(diaminomethylideneamino)propyl]-20-(1H-indol-3-ylmethyl)-26-(naphthalen-2-ylmethyl)-2,8,11,19,22,25,28-heptaoxo-1,7,12,18,21,24,27-heptazatricyclo[27.3.0.03,7]dotriacontane-17-carboxamide
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C58H78N14O10
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2
|
| 1 |
EC50 = 940 nM
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|
|
| 2 |
IC50 > 5000 nM
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CP0432500
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(2S,5R,8R,11S,14S,17S)-5-(3-amino-3-oxopropyl)-8-benzyl-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
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C42H58N12O8
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2
|
| 1 |
EC50 = 1000 nM
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|
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| 2 |
IC50 = 1000 nM
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CP0848656
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydro-1H-benzo[c]azepin-2(3H)-yl)-3-phenylpropanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C38H45N9O5
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2
|
| 1 |
EC50 = 1000 nM
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|
|
| 2 |
IC50 = 594 nM
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CP0849936
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(3R,4R,5S)-1-{[(3S,4R)-1-tert-Butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl}-3,5-dimethyl-4-phenylpiperidin-4-ol Hydrochloride
Show/Hide
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C28H37ClF2N2O2
|
1
|
| 1 |
EC50 = 1020 nM
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|
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CP0390604
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(S)-N-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
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C34H44N6O3
|
2
|
| 1 |
EC50 = 1070 nM
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|
|
| 2 |
Ki = 1793 nM
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|
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CP0421222
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2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]-2-oxo-3-propyl-piperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
Show/Hide
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C32H37FN4O4
|
2
|
| 1 |
EC50 = 1076 nM
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|
|
| 2 |
Ki = 1389 nM
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CP0374314
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((3R,4S)-1-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C28H36F2N2O2
|
1
|
| 1 |
EC50 = 1100 nM
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|
|
|
CP0845107
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(3R,4R,5S)-1-{[(3S,4R)-1-tert-Butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl}-4-(4-fluorophenyl)-3,5-dimethylpiperidin-4-ol Hydrochloride
Show/Hide
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C28H36ClF3N2O2
|
1
|
| 1 |
EC50 = 1120 nM
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|
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CP0400476
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
|
2
|
| 1 |
EC50 = 1160 nM
|
|
|
| 2 |
IC50 = 1050 nM
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|
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CP0402317
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-(pyridin-2-yl)piperidin-1-yl)methanone
Show/Hide
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C27H35F2N3O2
|
1
|
| 1 |
EC50 = 1170 nM
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|
|
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CP0376213
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,10-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
|
| 1 |
EC50 = 1171 nM
|
|
|
| 2 |
IC50 = 916 nM
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|
|
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CP0376385
|
(S)-2-acetamido-N-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(1H-imidazol-4-)propanamide
Show/Hide
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C36H44N8O4
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2
|
| 1 |
EC50 = 1220 nM
|
|
|
| 2 |
Ki = 2968 nM
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|
|
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CP0403297
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1-Pentanoylamino-4-phenyl-cyclohexanecarboxylic acid ((R)-1-{(S)-1-[(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide
Show/Hide
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C44H57N9O5
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1
|
| 1 |
EC50 = 1300 nM
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|
|
|
CP0421144
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1-Pentanoylamino-4-phenyl-cyclohexanecarboxylic acid ((S)-1-{(R)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-1H-indol-3-yl-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide
Show/Hide
|
C46H60N10O6
|
1
|
| 1 |
EC50 = 1300 nM
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|
|
|
CP0505663
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4-(4-Hydroxy-phenyl)-1-pentanoylamino-cyclohexanecarboxylic acid ((R)-1-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide
Show/Hide
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C46H60N10O7
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0408820
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-23-methyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
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C80H109N23O17S2
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2
|
| 1 |
EC50 = 1318.26 nM
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|
|
| 2 |
Ki = 4677.35 nM
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|
|
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CP0485886
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(2R,4R)-1-((R)-2-((S)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-3-phenylpropanoyl)-N-(2-guanidinoethyl)-4-(naphthalen-2-ylmethoxy)pyrrolidine-2-carboxamide
Show/Hide
|
C39H45N7O6
|
2
|
| 1 |
EC50 = 1337 nM
|
|
|
| 2 |
Ki = 2047 nM
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|
|
|
CP0394002
|
(S)-N-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
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C38H44N6O3
|
2
|
| 1 |
EC50 = 1362 nM
|
|
|
| 2 |
Ki = 1403 nM
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|
|
|
CP0372165
|
Ac-Tyr-Val-Nle-Gly-His-DPhe-trans-Xaa-Trp-Asp-Arg-Phe-Gly-NH2
Show/Hide
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C77H102N22O16
|
2
|
| 1 |
EC50 = 1400 nM
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|
|
| 2 |
IC50 = 830 nM
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|
|
|
CP0393623
|
(3S)-3-amino-4-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(1R,6aR,7S,10S,13S,16S,19S,22S,25S,31S,34S,37S,43S,46S,49S,55S,58S,61R,66R,69S,72S,75S,84S,88R,90S,93S,96S,99S)-19,37,49-tris(4-aminobutyl)-13,58-bis(2-amino-2-oxoethyl)-25,72-bis(3-amino-3-oxopropyl)-84-benzyl-93-(3-carbamimidamidopropyl)-46-(carboxymethyl)-6a-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-16,31-bis[(1R)-1-hydroxyethyl]-10,96,99-tris(hydroxymethyl)-75-(1H-imidazol-5-ylmethyl)-22,69,90-tris(2-methylpropyl)-a,2,8,8a,11,14,17,20,23,26,29,32,35,38,44,47,50,56,59,67,70,73,76,79,82,85,87,91,94,97-triacontaoxo-3a,4a,10a,11a,63,64-hexathia-1a,3,7a,9,12,15,18,21,24,27,30,33,36,39,45,48,51,57,60,68,71,74,77,80,83,86,89,92,95,98-triacontazahexacyclo[59.40.7.434,88.03,7.039,43.051,55]dodecahectan-66-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C165H262N52O51S6
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0423112
|
(S)-2-((S)-4-((R)-2-Amino-3-(4-fluorophenyl)propanoyl)-2-oxo-3-propylpiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
|
C30H35FN4O3
|
2
|
| 1 |
EC50 = 1505 nM
|
|
|
| 2 |
Ki = 10000 nM
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|
|
|
CP0423109
|
2-{4-[2-Amino-3-(4-fluoro-phenyl)-propionyl]-3-isopropyl-2-oxopiperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
Show/Hide
|
C30H35FN4O3
|
2
|
| 1 |
EC50 = 1523 nM
|
|
|
| 2 |
Ki = 10000 nM
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|
|
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CP0376220
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C56H75N15O9
|
2
|
| 1 |
EC50 = 1560 nM
|
|
|
| 2 |
IC50 = 111 nM
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|
|
|
CP0423111
|
(S)-2-((S)-4-((R)-2-Amino-3-(4-fluorophenyl)propanoyl)-3-ethyl-2-oxopiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
|
C29H33FN4O3
|
2
|
| 1 |
EC50 = 1697 nM
|
|
|
| 2 |
Ki = 10000 nM
|
|
|
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CP0387782
|
Ac-Nle-c[Asp-cis-4-guanidinyl-Pro-DNal(2')-Arg-Trp-Lys]-NH2
Show/Hide
|
C54H74N16O9
|
2
|
| 1 |
EC50 = 1700 nM
|
|
|
| 2 |
IC50 = 1.2 nM
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|
|
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CP0376437
|
(S)-2-acetamido-N-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(4-hydroxyphenyl)propanamide
Show/Hide
|
C39H46N6O5
|
2
|
| 1 |
EC50 = 1751 nM
|
|
|
| 2 |
Ki = 1687 nM
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|
|
|
CP0446498
|
(S)-2-acetamido-N-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(4-hydroxyphenyl)propanamide
Show/Hide
|
C39H46N6O5
|
2
|
| 1 |
EC50 = 1815 nM
|
|
|
| 2 |
Ki = 2454 nM
|
|
|
|
CP0430471
|
((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-(pyridin-2-yl)piperidin-1-yl)methanone
Show/Hide
|
C27H29F2N5O2
|
1
|
| 1 |
EC50 = 1850 nM
|
|
|
|
CP0382076
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C57H77N15O9
|
2
|
| 1 |
EC50 = 1970 nM
|
|
|
| 2 |
IC50 = 9.4 nM
|
|
|
|
CP0459828
|
(2R)-2-amino-3-(4-chlorophenyl)-1-[4-cyclohexyl-4-(1,2,4-triazol-1-ylmethyl)piperidin-1-yl]propan-1-one
Show/Hide
|
C23H32ClN5O
|
2
|
| 1 |
EC50 = 2000 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0376205
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-10-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C55H73N15O9
|
2
|
| 1 |
EC50 = 2210 nM
|
|
|
| 2 |
IC50 = 18.7 nM
|
|
|
|
CP0423110
|
2-{4-[2-Amino-3-(4-fluoro-phenyl)-propionyl]-3-methyl-2-oxopiperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
Show/Hide
|
C28H31FN4O3
|
2
|
| 1 |
EC50 = 2300 nM
|
|
|
| 2 |
Ki = 23400 nM
|
|
|
|
CP0375708
|
Ac-Nle-c[Asp-cis-4-guanidinyl-Pro-DPhe-Arg-Trp-Lys]-NH2
Show/Hide
|
C50H72N16O9
|
2
|
| 1 |
EC50 = 2700 nM
|
|
|
| 2 |
IC50 = 1.1 nM
|
|
|
|
CP0403308
|
N-[(2R)-1-[[(2S)-1-[[1-[(2-amino-2-oxoethyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-5-bromo-2-(pentanoylamino)-3,4-dihydro-1H-naphthalene-2-carboxamide
Show/Hide
|
C46H56BrN9O6
|
1
|
| 1 |
EC50 = 2900 nM
|
|
|
|
CP0432648
|
2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14,17,23-trimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
|
C82H113N23O17S2
|
2
|
| 1 |
EC50 = 3467.37 nM
|
|
|
| 2 |
Ki = 16982.44 nM
|
|
|
|
CP0374312
|
((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-propylpiperidin-1-yl)methanone
Show/Hide
|
C25H38F2N2O2
|
1
|
| 1 |
EC50 = 3610 nM
|
|
|
|
CP0845516
|
(3R,4R,5S)-1-{[(3S,4R)-4-(2,4-Difluorophenyl)-1-pyridazin-3-ylpyrrolidin-3-yl]carbonyl}-3,5-dimethyl-4-propylpiperidin-4-ol Hydrochloride
Show/Hide
|
C25H33ClF2N4O2
|
1
|
| 1 |
EC50 = 3900 nM
|
|
|
|
CP0911679
|
2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid ((R)-1-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide
Show/Hide
|
C43H54N10O6
|
1
|
| 1 |
EC50 = 4400 nM
|
|
|
|
CP0396404
|
(3S)-3-amino-4-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[(2S)-2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-5-amino-1-[[2-[[(2S,3R)-1-[[(2R)-1-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-4-amino-1-[[(2R)-1-[[(2R)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C165H268N52O51S6
|
1
|
| 1 |
EC50 = 4500 nM
|
|
|
|
CP0391042
|
((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(2,4-difluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
Show/Hide
|
C28H34F4N2O2
|
1
|
| 1 |
EC50 = 6570 nM
|
|
|
|
CP0436883
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(aR,1R,6S,9S,12S,15S,18S,21S,24S,30S,33R,36S,39S,45S,48S,51S,54R,59R,62S,65S,68S,77S,80R,83S,86R,89S,92S)-18,45,51-tris(4-aminobutyl)-24-(3-amino-3-oxopropyl)-12-benzyl-9,21-bis[(2S)-butan-2-yl]-39-(3-carbamimidamidopropyl)-77-(2-carboxyethyl)-a-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-15,30-bis[(1R)-1-hydroxyethyl]-65,68,89-tris(hydroxymethyl)-36,86-bis[(4-hydroxyphenyl)methyl]-48,92-dimethyl-83-(2-methylpropyl)-2a,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,63,66,69,72,75,78,81,84,87,90,93,95-triacontaoxo-62-propan-2-yl-4a,5a,56,57,97,98-hexathia-1a,2,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,61,64,67,70,73,76,79,82,85,88,91,94-triacontazatetracyclo[52.41.7.433,80.02,6]hexahectan-59-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
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C167H256N48O50S6
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2
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| 1 |
EC50 = 7400 nM
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| 2 |
IC50 = 26000 nM
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CP0371887
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4-[(3S,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-N-[2-(1H-indol-3-yl)ethyl]-4-oxobutanamide
Show/Hide
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C28H34N4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0371892
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1-((3R,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-3-(1H-indol-3-yl)propan-1-one
Show/Hide
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C25H29N3O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 4 nM
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CP0371896
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4-[(3R,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-N-[2-(1H-indol-3-yl)ethyl]-4-oxobutanamide
Show/Hide
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C28H34N4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0381774
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N-[(2S)-1-[(3S,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-3-(1H-indol-3-yl)propanamide
Show/Hide
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C31H41N7O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0381776
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1-((3R,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-phenylethanone
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C22H26N2O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1.3 nM
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CP0381777
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N-[6-[(3S,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-6-oxohexyl]-3-(1H-indol-3-yl)propanamide
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C31H40N4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0381817
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1-((3S,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-phenylethanone
Show/Hide
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C22H26N2O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 2.2 nM
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CP0424734
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1-((3S,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-3-(1H-indol-3-yl)propan-1-one
Show/Hide
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C25H29N3O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0378867
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(2S,5S,8R,11S,14S,17S)-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-5-propan-2-yl-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C46H61N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 4000 nM
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CP0403235
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(2S,5R,8R,11S,14S,17S)-2-butyl-5,11-bis[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C47H64N14O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1500 nM
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CP0403236
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2-[(2S,5S,8R,11S,14S,17S)-8-benzyl-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]acetic acid
Show/Hide
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C41H55N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0403237
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(2S,5R,8R,11S,14S,17S)-8-benzyl-2-butyl-5,11-bis[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C43H62N14O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1400 nM
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CP0403238
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(2S,5S,8R,11S,14S,17S)-8-benzyl-2,5-dibutyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C43H61N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0403239
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(3S,8S,11S,14S,17R,20R)-17-benzyl-3-butyl-14-[3-(diaminomethylideneamino)propyl]-11-(1H-indol-3-ylmethyl)-2,5,10,13,16,19-hexaoxo-1,4,9,12,15,18-hexazabicyclo[18.3.0]tricosane-8-carboxamide
Show/Hide
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C42H57N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0432499
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(2S,5S,8R,11S,14S,17S)-8-benzyl-2-butyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C43H57N13O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0432501
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2-[(2S,5R,8R,11S,14S,17S)-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]acetic acid
Show/Hide
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C45H57N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0432502
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(2S,5S,8R,11S,14S,17S)-8-benzyl-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-5-propan-2-yl-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C42H59N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0432515
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3-[(2S,5R,8R,11S,14S,17S)-8-benzyl-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]propanoic acid
Show/Hide
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C42H57N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0441512
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3-[(2S,5S,8R,11S,14S,17S)-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]propanoic acid
Show/Hide
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C46H59N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0441513
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(2S,5S,8R,11S,14S,17S)-2-butyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C47H59N13O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0442492
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(3S,8S,11S,14S,17R,20S)-3-butyl-14-[3-(diaminomethylideneamino)propyl]-11-(1H-indol-3-ylmethyl)-17-(naphthalen-2-ylmethyl)-2,5,10,13,16,19-hexaoxo-1,4,9,12,15,18-hexazabicyclo[18.3.0]tricosane-8-carboxamide
Show/Hide
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C46H59N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0378391
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(4R,7S,10S,13S)-4-benzyl-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,21,24-heptazabicyclo[18.4.0]tetracosa-1(24),20,22-triene-13-carboxamide
Show/Hide
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C38H46N12O6
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 412 nM
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CP0444828
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(2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-benzyl-5-(3-carbamimidamidopropyl)-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide
Show/Hide
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C52H69N13O8
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0462965
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(S)-3-((R)-2-acetamidohexanamido)-4-(2-((S)-1-((S)-1-((S)-1-((S)-1,6-diamino-1-oxohexan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-guanidino-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino)
Show/Hide
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C54H73N13O10
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0870610
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(3R,6S,9S,12R,15S)-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-12-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C46H49N13O8S
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 760 nM
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CP0374303
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyrimidin-2-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C28H30F2N4O2
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1
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| 1 |
EC50 > 10000 nM
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CP0378890
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 246 nM
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CP0382079
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C55H73N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 192 nM
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CP0400881
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-10,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 2520 nM
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CP0402318
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((3R,4S)-4-(2,4-difluorophenyl)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C29H36F2N2O3
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1
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| 1 |
EC50 > 11900 nM
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CP0374304
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridin-2-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C29H31F2N3O2
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1
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| 1 |
EC50 > 16700 nM
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CP0849935
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(3R,4R,5S)-4-Cyclopropyl-1-{[(3S,4R)-4-(2,4-difluorophenyl)-1-pyridazin-3-ylpyrrolidin-3-yl]carbonyl}-3,5-dimethylpiperidin-4-ol Hydrochloride
Show/Hide
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C25H31ClF2N4O2
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1
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| 1 |
EC50 > 16700 nM
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CP0377844
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Ac-Nle-c[Asp-His-DNal(2')-cis-4-guanidinyl-Pro-Trp-Lys]-NH2
Show/Hide
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C54H69N15O9
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2
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| 1 |
EC50 = 19000 nM
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| 2 |
IC50 = 400 nM
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CP0034706
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(S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid ((S)-1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-amide
Show/Hide
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C40H48N8O6
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2
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| 1 |
EC50 = 20000 nM
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| 2 |
Ki = 4520 nM
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CP0135132
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(2S)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)-N-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]pentanamide
Show/Hide
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C29H37N7O3
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2
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| 1 |
EC50 = 20000 nM
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| 2 |
Ki = 4384 nM
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CP0382252
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(2R)-2-amino-N-[3-cyclohexyl-4-(1,2,4-triazol-1-yl)butyl]-3-(4-fluorophenyl)propanamide
Show/Hide
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C21H30FN5O
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2
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| 1 |
EC50 > 25000 nM
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| 2 |
Ki > 10000 nM
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CP0454325
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(2R)-2-amino-N-[(2R)-1-cyclohexyl-5-(diaminomethylideneamino)pentan-2-yl]-3-(4-fluorophenyl)propanamide
Show/Hide
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C21H34FN5O
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1
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| 1 |
EC50 > 25000 nM
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CP0372759
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(2R)-2-amino-N-[(2S)-5-(diaminomethylideneamino)-1-piperidin-1-ylpentan-2-yl]-3-(4-fluorophenyl)propanamide
Show/Hide
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C20H33FN6O
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2
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| 1 |
EC50 > 50000 nM
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| 2 |
Ki > 100000 nM
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CP0404966
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(2R)-2-amino-N-[(2S)-5-(diaminomethylideneamino)-1-oxo-1-piperidin-1-ylpentan-2-yl]-3-(4-fluorophenyl)propanamide
Show/Hide
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C20H31FN6O2
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2
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| 1 |
EC50 > 50000 nM
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| 2 |
Ki > 100000 nM
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CP0375710
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AC-Nle-c[Asp-His-DPhe-Pro-Trp-Lys]-NH2
Show/Hide
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C49H64N12O9
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 4800 nM
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CP0432503
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(2S,5S,8R,11S,14S,17S)-2,5-dibutyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C47H63N11O7
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 3000 nM
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CP0432514
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(2S,5S,8R,11S,14S,17S)-5-(3-amino-3-oxopropyl)-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C46H60N12O8
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 1000 nM
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CP0378445
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(4R,7S,10S,13S)-4-benzyl-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,24-hexazabicyclo[18.3.1]tetracosa-1(23),20(24),21-triene-13-carboxamide
Show/Hide
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C39H47N11O6
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 10000 nM
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CP0412765
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(2R,5S,8S,11S,25S)-25-amino-5-[3-(diaminomethylideneamino)propyl]-8-(1H-indol-3-ylmethyl)-2-(naphthalen-2-ylmethyl)-3,6,9,17,20,26-hexaoxo-1,4,7,10,16-pentazacyclohexacosane-11-carboxamide
Show/Hide
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C46H61N11O7
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 2000 nM
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CP0858764
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(3R,6S,9S,12R)-12-benzyl-9-(3-carbamimidamidopropyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-1',3',3,4,5,6,7,8,9,10,11,12,13,14,16,17-hexadecahydro-2H-spiro[1,4,7,10,13,16-benzothiapentazacyclononadecine-15,2'-indene]-3-carboxamide
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C46H49N11O8S
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 1000 nM
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CP0873314
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(3R,6S,9S,12S,15S)-12-[(4-aminophenyl)methyl]-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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C42H48N14O8S
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 10000 nM
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CP0376207
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,10,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C57H77N15O9
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 824 nM
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CP0377558
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(3R,6R,14R,17S,20S,23S,26R)-6-[[(2S)-2-acetamidohexanoyl]amino]-20-[3-(diaminomethylideneamino)propyl]-3,17-bis(1H-indol-3-ylmethyl)-23-(naphthalen-2-ylmethyl)-2,5,8,16,19,22,25-heptaoxo-1,4,9,15,18,21,24-heptazabicyclo[24.3.0]nonacosane-14-carboxamide
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C64H81N15O10
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1
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| 1 |
EC50 > 1000 nM
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CP0402864
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C72H101N19O15
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1
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| 1 |
EC50 > 1000 nM
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CP0407291
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C72H100N16O15
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 1.1 nM
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CP0460800
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2-[(1R,4S,7S,13S,16S,19S,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C79H107N23O17S2
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1
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| 1 |
EC50 > 1000 nM
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CP0389090
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(2S)-1-acetyl-N-[(2R)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-fluorophenyl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
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C33H41FN6O5
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 0.74 nM
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CP0392441
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(2S)-1-acetyl-N-[(2R)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-bromophenyl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
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C33H41BrN6O5
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 80 nM
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CP0551927
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-21,21-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(28),24,26-triene-5-carboxamide
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C56H74N14O8S2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 70 nM
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CP0485356
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(2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-5-(3-carbamimidamidopropyl)-8-(1H-indol-3-ylmethyl)-2-(naphthalen-2-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide
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C56H71N13O8
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2
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| 1 |
EC50 > 2500 nM
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| 2 |
IC50 = 580 nM
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CP0378449
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(4R,7S,10S,13S)-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-4-(naphthalen-2-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,21,24-heptazabicyclo[18.4.0]tetracosa-1(24),20,22-triene-13-carboxamide
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C42H48N12O6
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 707 nM
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CP0269557
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-1-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide
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C32H34ClN7O2
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1
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| 1 |
EC50 > 3000 nM
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CP0393281
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-4-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide
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C32H34ClN7O2
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1
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| 1 |
EC50 > 3000 nM
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CP0376221
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C57H77N15O9
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3
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 242 nM
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| 3 |
Kd = 31.62 nM
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CP0388955
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7,10-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C57H77N15O9
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 256 nM
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CP0400031
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C28H30F2N4O2
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1
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| 1 |
EC50 > 3070 nM
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CP0374306
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((3R,4S)-1-cyclopropyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C27H32F2N2O2
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1
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| 1 |
EC50 > 4910 nM
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CP0372164
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Ac-Tyr-Val-Nle-Gly-His-DPhe-cis-Xaa-Trp-Asp-Arg-Phe-Gly-NH2
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C77H102N22O16
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2
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| 1 |
EC50 > 5000 nM
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| 2 |
IC50 = 1000 nM
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CP0378387
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(7S,10R,13S,16S,19S)-13-[3-(diaminomethylideneamino)propyl]-16-(1H-indol-3-ylmethyl)-10-(naphthalen-2-ylmethyl)-2,8,11,14,17,25-hexaoxo-3,9,12,15,18,24-hexazatricyclo[24.4.0.03,7]triaconta-1(30),26,28-triene-19-carboxamide
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C49H57N11O7
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2
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| 1 |
EC50 > 5000 nM
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| 2 |
IC50 = 410 nM
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CP0462856
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(2,6-difluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
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C28H34F4N2O2
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1
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| 1 |
EC50 > 5010 nM
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CP0401418
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(4-chlorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
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C28H35ClF2N2O2
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1
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| 1 |
EC50 > 5880 nM
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CP0401674
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((3S,4R)-4-(2,4-difluorophenyl)-1-methylpyrrolidin-3-yl)((3S,4R,5R)-4-(4-fluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
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C25H29F3N2O2
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1
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| 1 |
EC50 > 6150 nM
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CP0374301
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(3-fluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
Show/Hide
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C28H35F3N2O2
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1
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| 1 |
EC50 > 6470 nM
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CP0858960
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(3R,4R,5S)-1-{[(3S,4R)-4-(2,4-Difluorophenyl)-1-methylpyrrolidin-3-yl]carbonyl}-3,5-dimethyl-4-phenylpiperidin-4-ol Hydrochloride
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C25H31ClF2N2O2
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1
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| 1 |
EC50 > 7810 nM
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CP0430472
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridin-3-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C29H31F2N3O2
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1
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| 1 |
EC50 > 8220 nM
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CP0391026
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((3S,4R)-4-(2,4-difluorophenyl)-1-ethylpyrrolidin-3-yl)((3S,4R,5R)-4-(3-fluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
Show/Hide
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C26H31F3N2O2
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1
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| 1 |
EC50 > 8250 nM
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CP0383467
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((3S,4R)-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C24H28F2N2O2
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1
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| 1 |
EC50 > 8740 nM
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CP0383465
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyrimidin-4-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C28H30F2N4O2
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1
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| 1 |
EC50 > 9000 nM
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CP0407275
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C74H101N17O15
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1
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| 1 |
IC50 = 16 nM
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CP0577292
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-21,21-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
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C56H74N14O8S2
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1
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| 1 |
IC50 = 150 nM
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CP0571200
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-21,21-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
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C56H74N14O8S2
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1
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| 1 |
IC50 = 227 nM
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CP0568756
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4,21,21-tetramethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
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C58H78N14O8S2
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1
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| 1 |
IC50 = 450 nM
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CP0543865
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4,21,21-tetramethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
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C58H78N14O8S2
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1
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| 1 |
IC50 = 553 nM
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CP0439622
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Ac-c[Glu-His-D-Phe-N-alpha-guanidinylbutyl-Orn]-Trp-NH2
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C43H57N13O7
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1
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| 1 |
IC50 = 750 nM
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CP0376307
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Ac-c[Cys-His-D-Phe-N-alpha-guanidinylbutyl-D-Cys]-Trp-NH2
Show/Hide
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C39H50N12O6S2
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1
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| 1 |
IC50 = 1000 nM
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CP0859091
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-phenylpropanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C40H46N10O5
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1
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| 1 |
IC50 = 1352 nM
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CP0372162
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Ac-Nle-c[Asp-His-DPhe-trans-4-guanidinyl-Pro-Trp-Lys]-NH2
Show/Hide
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C50H67N15O9
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1
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| 1 |
IC50 = 3500 nM
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CP0422316
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Ac-c[Glu-His-D-Nal(2)'-N-alpha-guanidinylbutyl-Orn]-Trp-NH2
Show/Hide
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C47H59N13O7
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1
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| 1 |
IC50 > 10000 nM
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CP0378446
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(4R,7S,10S,13S)-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-4-(naphthalen-2-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,24-hexazabicyclo[18.3.1]tetracosa-1(23),20(24),21-triene-13-carboxamide
Show/Hide
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C43H49N11O6
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1
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| 1 |
IC50 > 10000 nM
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CP0378448
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(2R,5S,8S,11S,25S)-25-amino-2-benzyl-5-[3-(diaminomethylideneamino)propyl]-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,26-hexaoxo-1,4,7,10,16-pentazacyclohexacosane-11-carboxamide
Show/Hide
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C42H59N11O7
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1
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| 1 |
IC50 > 10000 nM
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CP0384353
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(11S,14S,17S,20R,23S)-20-benzyl-17-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-2,13,16,19,22-pentaoxo-1,6,12,15,18,21-hexazabicyclo[21.3.0]hexacosane-11-carboxamide
Show/Hide
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C41H57N11O6
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1
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| 1 |
IC50 > 10000 nM
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CP0384356
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(7S,10R,13S,16S,19S)-13-[3-(diaminomethylideneamino)propyl]-16-(1H-indol-3-ylmethyl)-10-(naphthalen-2-ylmethyl)-2,8,11,14,17,28-hexaoxo-3,9,12,15,18,24-hexazatricyclo[27.4.0.03,7]tritriaconta-1(33),29,31-triene-19-carboxamide
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C52H63N11O7
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1
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| 1 |
IC50 > 10000 nM
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CP0427899
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(7S,10R,13S,16S,19S)-10-benzyl-13-[3-(diaminomethylideneamino)propyl]-16-(1H-indol-3-ylmethyl)-2,8,11,14,17,25-hexaoxo-3,9,12,15,18,24-hexazatricyclo[24.4.0.03,7]triaconta-1(30),26,28-triene-19-carboxamide
Show/Hide
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C45H55N11O7
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1
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| 1 |
IC50 > 10000 nM
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CP0847693
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(3R,6S,9S,12S,25aS)-3-benzyl-6-(3-carbamimidamidopropyl)-9-(1H-indol-3-ylmethyl)-1,4,7,10,18,21-hexaoxo-1H,2H,3H,4H,5H,6H,7H,8H,9H,10H,11H,12H,13H,14H,15H,16H,17H,18H,21H,23H,24H,25H,25aH-pyrrolo[2,1-l]1,4,7,10,13,18-hexaazacyclotricosane-12-carboxamide
Show/Hide
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C41H53N11O7
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1
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| 1 |
IC50 > 10000 nM
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CP0850181
|
(3R,6S,9S,12S,25aS)-6-(3-carbamimidamidopropyl)-9-(1H-indol-3-ylmethyl)-3-(naphthalen-2-ylmethyl)-1,4,7,10,18,21-hexaoxo-1H,2H,3H,4H,5H,6H,7H,8H,9H,10H,11H,12H,13H,14H,15H,16H,17H,18H,21H,23H,24H,25H,25aH-pyrrolo[2,1-l]1,4,7,10,13,18-hexaazacyclotricosane-12-carboxamide
Show/Hide
|
C45H55N11O7
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0376305
|
Ac-c[Cys-His-D-Nal(2)'-Cys]-N-alpha-guanidinylbutyl-D-Trp-NH2
Show/Hide
|
C43H52N12O6S2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0381773
|
Ac-c[Cys-His-D-Phe-Cys]-N-alpha-guanidinylbutyl-Trp-NH2
Show/Hide
|
C39H50N12O6S2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0453648
|
Ac-c[Glu-His-D-Phe-N-alpha-guanidinylbutyl-Dab]-Trp-NH2
Show/Hide
|
C42H55N13O7
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0870609
|
(7S,10R,13S,16S,19R)-10-benzyl-13-(3-carbamimidamidopropyl)-19-carbamoyl-16-(1H-indol-3-ylmethyl)-N-methyl-N,2,8,11,14,17-hexaoxo-21-thia-3,9,12,15,18-pentaazatricyclo[20.4.0.0^{3,7}]hexacosa-1(26),22,24-trien-25-aminium
Show/Hide
|
C41H47N11O8S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0877951
|
(3R,6S,9S,12R,15S)-6,12-dibenzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
|
C40H46N12O8S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0576761
|
(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4,21,21-tetramethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
Show/Hide
|
C58H78N14O8S2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0870112
|
(7R,10R,13S,16S,19R)-10-benzyl-13-(3-carbamimidamidopropyl)-19-carbamoyl-16-(1H-indol-3-ylmethyl)-N-methyl-N,2,8,11,14,17-hexaoxo-21-thia-3,9,12,15,18-pentaazatricyclo[20.4.0.0^{3,7}]hexacosa-1(26),22,24-trien-25-aminium
Show/Hide
|
C41H47N11O8S
|
1
|
| 1 |
IC50 > 1500 nM
|
|
|
|
CP0858763
|
(3R,6S,9S,12S,15S)-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-12-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
|
C46H49N13O8S
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
|
CP0375709
|
Ac-Nle-c[Asp-His-DNal(2')-trans-4-guanidinyl-Pro-Trp-Lys]-NH2
Show/Hide
|
C54H69N15O9
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0870732
|
US9447148, 9.1
Show/Hide
|
C51H71N15O9
|
1
|
| 1 |
Ki = 0.01 nM
|
|
|
|
CP0870733
|
US9447148, 9.21
Show/Hide
|
C48H64N14O8
|
1
|
| 1 |
Ki = 0.01 nM
|
|
|
|
CP0914914
|
US9447148, 9.22
Show/Hide
|
C49H66N14O8
|
1
|
| 1 |
Ki = 0.01 nM
|
|
|
|
CP0951276
|
US9447148, 9.10
Show/Hide
|
C51H68N14O9
|
1
|
| 1 |
Ki = 0.01 nM
|
|
|
|
CP0904791
|
US9447148, 9.18
Show/Hide
|
C48H66N14O8
|
1
|
| 1 |
Ki = 0.015 nM
|
|
|
|
CP0926758
|
US9447148, 9.27
Show/Hide
|
C52H72N16O10
|
1
|
| 1 |
Ki = 0.015 nM
|
|
|
|
CP0929620
|
US9447148, 9.11
Show/Hide
|
C51H68N14O9
|
1
|
| 1 |
Ki = 0.02 nM
|
|
|
|
CP0904525
|
US9447148, 9.20
Show/Hide
|
C48H64N14O8
|
1
|
| 1 |
Ki = 0.025 nM
|
|
|
|
CP0908209
|
US9447148, 9.17
Show/Hide
|
C47H64N14O8
|
1
|
| 1 |
Ki = 0.025 nM
|
|
|
|
CP0915676
|
US9447148, 9.29
Show/Hide
|
C51H70N16O10
|
1
|
| 1 |
Ki = 0.025 nM
|
|
|
|
CP0904520
|
US9447148, 9.24
Show/Hide
|
C50H62N14O8
|
1
|
| 1 |
Ki = 0.03 nM
|
|
|
|
CP0908210
|
US9447148, 9.28
Show/Hide
|
C50H68N16O10
|
1
|
| 1 |
Ki = 0.03 nM
|
|
|
|
CP0904522
|
US9447148, 9.3
Show/Hide
|
C48H65N15O9
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0904780
|
US9447148, 9.23
Show/Hide
|
C49H60N14O8
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0929640
|
US9447148, 9.43
Show/Hide
|
C51H70N16O10
|
1
|
| 1 |
Ki = 0.065 nM
|
|
|
|
CP0951277
|
US9447148, 9.6
Show/Hide
|
C50H69N15O9
|
1
|
| 1 |
Ki = 0.07 nM
|
|
|
|
CP0378500
|
Ac-YRMEHdFRWGSPPKD-NH2
Show/Hide
|
C84H119N25O21S
|
1
|
| 1 |
Ki = 0.09 nM
|
|
|
|
CP0166249
|
(4S)-5-[(2S)-1-[(2S)-1-[(2S)-1-[(2S)-1-[2-[(2S)-6-amino-1-[(2S)-2-[N-[(2S)-1-(carboxymethylimino)-1-hydroxy-3-methylbutan-2-yl]-C-hydroxycarbonimidoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]imino-2-hydroxyethyl]imino-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]imino-5-carbamimidamido-1-hydroxypentan-2-yl]imino-1-hydroxy-3-phenylpropan-2-yl]imino-1-hydroxy-3-(1H-imidazol-5-yl)propan-2-yl]imino-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[[(2S)-1-[(2S)-2-[[(2S)-2-amino-1,4-dihydroxy-4-iminobutylidene]amino]-3-carboxypropanoyl]pyrrolidin-2-yl]-hydroxymethylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-4-methylsulfanylbutylidene]amino]-5-hydroxypentanoic acid
Show/Hide
|
C90H127N25O26S
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0911418
|
US9447148, 9.9
Show/Hide
|
C51H68N14O9
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0921410
|
US8846601, 153
Show/Hide
|
C46H62N14O8
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0904297
|
US9040663, 16
Show/Hide
|
C49H73N17O10
|
1
|
| 1 |
Ki = 0.15 nM
|
|
|
|
CP0908213
|
US9447148, 9.13
Show/Hide
|
C52H65N15O9
|
1
|
| 1 |
Ki = 0.195 nM
|
|
|
|
CP0852682
|
US9040663, 5
Show/Hide
|
C48H69Cl2N17O9
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0439884
|
Ac-YRMEHdFRWG-NH2
Show/Hide
|
C61H83N19O13S
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0859361
|
US9040663, 3
Show/Hide
|
C48H70ClN17O9
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0870723
|
US9447148, 9.5
Show/Hide
|
C46H62N14O8S2
|
1
|
| 1 |
Ki = 0.35 nM
|
|
|
|
CP0904782
|
US9447148, 9.12
Show/Hide
|
C52H65N15O9
|
1
|
| 1 |
Ki = 0.35 nM
|
|
|
|
CP0867208
|
US9040663, 4
Show/Hide
|
C48H69Cl2N17O9
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0951453
|
US9040663, 11
Show/Hide
|
C48H70FN17O9
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0378499
|
(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[(2S)-2-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-amino-3-carboxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
|
C89H127N27O22S
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0870724
|
US9447148, 9.7
Show/Hide
|
C49H67N15O9
|
1
|
| 1 |
Ki = 0.55 nM
|
|
|
|
CP0847736
|
Ac-YR[CEHdFRWC]SPPKD-NH2
Show/Hide
|
C83H115N25O21S2
|
1
|
| 1 |
Ki = 0.57 nM
|
|
|
|
CP0870725
|
US9447148, 9.15
Show/Hide
|
C45H60N14O8
|
1
|
| 1 |
Ki = 0.65 nM
|
|
|
|
CP0879027
|
US9040663, 54
Show/Hide
|
C50H68F2N18O9
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0881744
|
US9040663, 15
Show/Hide
|
C49H73N17O9
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0946855
|
US9040663, 53
Show/Hide
|
C50H69FN18O9
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0868214
|
US9040663, 9
Show/Hide
|
C48H70FN17O9
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0434327
|
Beta MSH
Show/Hide
|
C118H174N34O35S
|
1
|
| 1 |
Ki = 0.89 nM
|
|
|
|
CP0859185
|
US9040663, 57
Show/Hide
|
C50H69FN18O9
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0892018
|
US9040663, 1
Show/Hide
|
C48H70ClN17O9
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0954809
|
US9040663, 2
Show/Hide
|
C48H70ClN17O9
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0904523
|
US9447148, 9.26
Show/Hide
|
C48H64N14O10
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0850485
|
US9040663, 50
Show/Hide
|
C50H69ClN18O9
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0861338
|
US9040663, 10
Show/Hide
|
C48H70FN17O9
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0423940
|
US9447148, 9.64
Show/Hide
|
C38H62N12O9
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0474882
|
US9447148, 9.59
Show/Hide
|
C37H59ClN12O8
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0870717
|
US9447148, 9.25
Show/Hide
|
C41H62N14O9
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0870722
|
US9447148, 9.4
Show/Hide
|
C47H63N15O9
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0908211
|
US9447148, 9.8
Show/Hide
|
C49H67N15O9
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0464640
|
Ac-YRC(Me)*EHdFRWC(Me)NH2
Show/Hide
|
C62H85N19O13S2
|
1
|
| 1 |
Ki = 2.73 nM
|
|
|
|
CP0871143
|
US9040663, 13
Show/Hide
|
C49H70F3N17O9
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0908344
|
US9040663, 51
Show/Hide
|
C50H69ClN18O9
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0423973
|
US9447148, 9.63
Show/Hide
|
C38H62N12O8
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0870738
|
US9447148, 9.66
Show/Hide
|
C48H67N13O9
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0966841
|
US9447148, 9.19
Show/Hide
|
C45H58N14O8
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0493416
|
US9447148, 9.56
Show/Hide
|
C37H60N12O8
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0911495
|
US9040663, 7
Show/Hide
|
C49H70N18O9
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0866686
|
US9040663, 52
Show/Hide
|
C51H69N19O9
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0903290
|
US9040663, 49
Show/Hide
|
C49H71ClN16O10
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0439876
|
Ac-YR[CEH(pCl-dF)RWC]-NH2
Show/Hide
|
C60H78ClN19O13S2
|
1
|
| 1 |
Ki = 8.22 nM
|
|
|
|
CP0954861
|
US9040663, 14
Show/Hide
|
C49H70F3N17O9
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0485105
|
Ac-YR[CEH(pF-dF)RWC]-NH2
Show/Hide
|
C60H78FN19O13S2
|
1
|
| 1 |
Ki = 9.91 nM
|
|
|
|
CP0486687
|
Ac-R[CEHdFRWC]-NH2
Show/Hide
|
C51H70N18O11S2
|
1
|
| 1 |
Ki = 10.34 nM
|
|
|
|
CP0850488
|
US9040663, 63
Show/Hide
|
C55H75ClN16O10
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0863128
|
US9040663, 8
Show/Hide
|
C48H71N17O10
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0486686
|
Ac-YK[CEHdFRWC]-NH2
Show/Hide
|
C60H79N17O13S2
|
1
|
| 1 |
Ki = 15.76 nM
|
|
|
|
CP0185382
|
Ac-dR[CEHdFRWC]-NH2
Show/Hide
|
C51H70N18O11S2
|
1
|
| 1 |
Ki = 16.78 nM
|
|
|
|
CP0276967
|
Ac-YR[CEHdFRWC]-NH2
Show/Hide
|
C60H79N19O13S2
|
1
|
| 1 |
Ki = 17.12 nM
|
|
|
|
CP0486280
|
US9447148, 9.60
Show/Hide
|
C37H59FN12O8
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0548110
|
US9447148, 9.61
Show/Hide
|
C37H59FN12O8
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0894521
|
US9040663, 55
Show/Hide
|
C49H71ClN16O10
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0868956
|
US9040663, 47
Show/Hide
|
C54H73ClN16O10
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0953530
|
US9040663, 61
Show/Hide
|
C47H68ClN17O9
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0160526
|
(R)-N-((R)-1-(4-(2-(aminomethyl)phenyl)piperazin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
|
C30H34ClN5O2
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0880919
|
US9040663, 62
Show/Hide
|
C47H68ClN17O9
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0861443
|
US9040663, 56
Show/Hide
|
C50H72ClN17O10
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0481221
|
US9447148, 9.57
Show/Hide
|
C37H59ClN12O8
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0902211
|
US9040663, 68
Show/Hide
|
C49H71FN16O11S
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0951412
|
US9040663, 12
Show/Hide
|
C49H70N18O9
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0497596
|
US9447148, 9.58
Show/Hide
|
C37H59ClN12O8
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0481223
|
US9447148, 9.62
Show/Hide
|
C37H58F2N12O8
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0437137
|
1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-{[2-(2-fluoro-phenyl)-ethylamino]-methyl}-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
Show/Hide
|
C38H41ClFN5O2
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0863227
|
US9040663, 65
Show/Hide
|
C47H67FN16O10
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0954249
|
US9040663, 6
Show/Hide
|
C49H70N18O9
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0403125
|
Ac-YCit[CEHdFRWC]-NH2
Show/Hide
|
C60H78N18O14S2
|
1
|
| 1 |
Ki = 49.42 nM
|
|
|
|
CP0894653
|
US9040663, 64
Show/Hide
|
C49H69FN16O10
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0874197
|
US9040663, 59
Show/Hide
|
C49H70FN17O10
|
1
|
| 1 |
Ki = 58 nM
|
|
|
|
CP0870297
|
2-{3-(2-Amino-ethyl-guanidino)-4-[2-amino-3-(4-fluoro-phenyl)-propionyl]-2-oxo-piperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
Show/Hide
|
C30H35FN8O3
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0485106
|
Ac-[CEHdFRWC]-NH2
Show/Hide
|
C45H58N14O10S2
|
1
|
| 1 |
Ki = 67.09 nM
|
|
|
|
CP0946748
|
US9040663, 112
Show/Hide
|
C49H70ClN17O10
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0967672
|
US9040663, 60
Show/Hide
|
C49H69FN16O10
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0894652
|
US9040663, 114
Show/Hide
|
C50H70F3N17O10
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0904282
|
US9040663, 66
Show/Hide
|
C49H69FN16O9
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0940773
|
US9040663, 110
Show/Hide
|
C50H73N17O10
|
1
|
| 1 |
Ki = 105 nM
|
|
|
|
CP0439875
|
Ac-YR[CEH(d-2alpha-Nal)RWC]-NH2
Show/Hide
|
C64H81N19O13S2
|
1
|
| 1 |
Ki = 121.3 nM
|
|
|
|
CP0870071
|
US9040663, 34
Show/Hide
|
C49H70ClN17O10
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0903039
|
US9040663, 58
Show/Hide
|
C47H67FN16O10
|
1
|
| 1 |
Ki = 138 nM
|
|
|
|
CP0954266
|
US9040663, 33
Show/Hide
|
C49H69ClN16O10
|
1
|
| 1 |
Ki = 143 nM
|
|
|
|
CP0860082
|
US9040663, 111
Show/Hide
|
C50H73N17O10
|
1
|
| 1 |
Ki = 145 nM
|
|
|
|
CP0877876
|
Ac-YR[CEHFRWC]-NH2
Show/Hide
|
C60H79N19O13S2
|
1
|
| 1 |
Ki = 147.07 nM
|
|
|
|
CP0850385
|
US9040663, 69
Show/Hide
|
C48H68FN17O10
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0853156
|
US9040663, 73
Show/Hide
|
C49H71N17O10
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0896802
|
US9040663, 70
Show/Hide
|
C48H68FN17O10
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0861253
|
US9040663, 75
Show/Hide
|
C48H67F2N17O10
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0953274
|
US9040663, 77
Show/Hide
|
C48H67F2N17O10
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0874273
|
US9040663, 82
Show/Hide
|
C49H70FN17O10
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0875512
|
US9040663, 115
Show/Hide
|
C50H70F3N17O10
|
1
|
| 1 |
Ki = 235 nM
|
|
|
|
CP0937294
|
US9040663, 84
Show/Hide
|
C48H68FN17O10
|
1
|
| 1 |
Ki = 245 nM
|
|
|
|
CP0951809
|
US9040663, 113
Show/Hide
|
C48H68ClN17O10
|
1
|
| 1 |
Ki = 255 nM
|
|
|
|
CP0845657
|
US9040663, 76
Show/Hide
|
C48H67F2N17O10
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0850864
|
US9040663, 83
Show/Hide
|
C49H70FN17O10
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0899829
|
US9040663, 38
Show/Hide
|
C49H70ClN17O10
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0859903
|
US9040663, 31
Show/Hide
|
C47H67ClN16O10
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0908214
|
US9447148, 9.14
Show/Hide
|
C40H51N13O7
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0880928
|
US9040663, 71
Show/Hide
|
C48H68FN17O10
|
1
|
| 1 |
Ki = 335 nM
|
|
|
|
CP0859358
|
US9040663, 36
Show/Hide
|
C48H69ClN16O10
|
1
|
| 1 |
Ki = 380 nM
|
|
|
|
CP0859360
|
US9040663, 116
Show/Hide
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C49H68F3N17O10
|
1
|
| 1 |
Ki = 380 nM
|
|
|
|
CP0863154
|
US9040663, 79
Show/Hide
|
C49H70ClN17O10
|
1
|
| 1 |
Ki = 395 nM
|
|
|
|
CP0958671
|
US9040663, 74
Show/Hide
|
C49H71N17O10
|
1
|
| 1 |
Ki = 405 nM
|
|
|
|
CP0911705
|
US9040663, 42
Show/Hide
|
C50H71N17O9
|
1
|
| 1 |
Ki = 420 nM
|
|
|
|
CP0902185
|
US9040663, 46
Show/Hide
|
C50H70N18O10
|
1
|
| 1 |
Ki = 425 nM
|
|
|
|
CP0875437
|
US9040663, 37
Show/Hide
|
C49H69ClN16O10
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0902182
|
US9040663, 78
Show/Hide
|
C49H69F2N17O10
|
1
|
| 1 |
Ki = 515 nM
|
|
|
|
CP0866646
|
US9040663, 32
Show/Hide
|
C48H69ClN16O10
|
1
|
| 1 |
Ki = 540 nM
|
|
|
|
CP0871145
|
US9040663, 117
Show/Hide
|
C49H68F3N17O10
|
1
|
| 1 |
Ki = 540 nM
|
|
|
|
CP0874285
|
US9040663, 48
Show/Hide
|
C54H72ClN17O10
|
1
|
| 1 |
Ki = 545 nM
|
|
|
|
CP0867710
|
US9040663, 35
Show/Hide
|
C47H67ClN16O10
|
1
|
| 1 |
Ki = 810 nM
|
|
|
|
CP0940834
|
US9040663, 43
Show/Hide
|
C49H68N18O10
|
1
|
| 1 |
Ki = 870 nM
|
|
|
|
CP0912592
|
US9040663, 40
Show/Hide
|
C50H69N17O10
|
1
|
| 1 |
Ki = 880 nM
|
|
|
|
CP0392260
|
2-fluoroethyl N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]carbamate
Show/Hide
|
C29H33Cl2FN4O3S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0081762
|
(S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propanoyl)-3-(2-guanidinoethyl)-2-oxopiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
|
C30H36FN7O3
|
1
|
| 1 |
Ki = 1120 nM
|
|
|
|
CP0442321
|
4-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-butyramide
Show/Hide
|
C30H38ClN5O2S
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0399948
|
3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-propionamide
Show/Hide
|
C29H36ClN5O2S
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0378145
|
(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[1-(piperidin-3-ylamino)-ethyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
Show/Hide
|
C36H45ClN6O2
|
1
|
| 1 |
Ki = 1500 nM
|
|
|
|
CP0908357
|
US9040663, 39
Show/Hide
|
C50H69N17O9
|
1
|
| 1 |
Ki = 1550 nM
|
|
|
|
CP0900804
|
US9040663, 44
Show/Hide
|
C49H69N17O10
|
1
|
| 1 |
Ki = 1625 nM
|
|
|
|
CP0923199
|
US9040663, 80
Show/Hide
|
C49H70ClN17O10
|
1
|
| 1 |
Ki = 1750 nM
|
|
|
|
CP0377910
|
1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[1-((S)-pyrrolidin-3-ylamino)-ethyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
Show/Hide
|
C35H43ClN6O2
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0423941
|
US9447148, 9.65
Show/Hide
|
C37H57N11O8
|
1
|
| 1 |
Ki = 2250 nM
|
|
|
|
CP0430024
|
N-[(2R)-3-(4-chlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]piperidine-3-carboxamide
Show/Hide
|
C32H40ClN5O2S
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0896490
|
US9040663, 72
Show/Hide
|
C49H71N17O10
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0448705
|
3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-[4-(1-{[2-(3-methoxy-phenyl)-acetylamino]-methyl}-cyclohexyl)-piperazin-1-yl]-2-oxo-ethyl}-propionamide
Show/Hide
|
C32H43Cl2N5O4
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0424915
|
N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamide
Show/Hide
|
C36H45ClFN5O2
|
1
|
| 1 |
Ki = 3000 nM
|
|
|
|
CP0453047
|
(1S)-(2-{4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]-1-piperazinyl}-5-methylphenyl)-3-methylbutylamine
Show/Hide
|
C26H36ClN3O
|
1
|
| 1 |
Ki = 3100 nM
|
|
|
|
CP0866274
|
US9040663, 86
Show/Hide
|
C50H69N17O11
|
1
|
| 1 |
Ki = 3968 nM
|
|
|
|
CP0466190
|
1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-imidazol-1-ylmethyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
Show/Hide
|
C33H35ClN6O2
|
1
|
| 1 |
Ki = 4000 nM
|
|
|
|
CP0234419
|
(R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(thiophen-2-yl)ethylamino)methyl)phenyl)piperazin-1-yl)propan-2-yl)propanamide
Show/Hide
|
C29H35Cl2N5O2S
|
1
|
| 1 |
Ki = 4200 nM
|
|
|
|
CP0904726
|
US9040663, 41
Show/Hide
|
C48H67N17O9
|
1
|
| 1 |
Ki = 4300 nM
|
|
|
|
CP0423108
|
2-{4-[2-Amino-3-(4-fluoro-phenyl)-propionyl]-3-[2-(pyridin-2-ylamino)-ethyl]-piperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
Show/Hide
|
C34H37FN6O3
|
1
|
| 1 |
Ki = 4469 nM
|
|
|
|
CP0378182
|
3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-[4-(1-{[(thiophen-2-ylmethyl)-amino]-methyl}-cyclohexyl)-piperazin-1-yl]-ethyl}-propionamide
Show/Hide
|
C28H39Cl2N5O2S
|
1
|
| 1 |
Ki = 4500 nM
|
|
|
|
CP0391936
|
3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-{1-[(2-thiophen-2-yl-acetylamino)-methyl]-cyclohexyl}-piperazin-1-yl)-ethyl]-propionamide
Show/Hide
|
C29H39Cl2N5O3S
|
1
|
| 1 |
Ki = 4600 nM
|
|
|
|
CP0422196
|
(R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(1-((2-(4-methoxyphenyl)acetamido)methyl)cyclohexyl)piperazin-1-yl)-1-oxopropan-2-yl)propanamide
Show/Hide
|
C32H43Cl2N5O4
|
1
|
| 1 |
Ki = 5700 nM
|
|
|
|
CP0424911
|
(R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamino)-1-(2-fluorophenyl)ethyl)piperazin-1-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
|
C35H43ClFN5O2
|
1
|
| 1 |
Ki = 5800 nM
|
|
|
|
CP0081758
|
(S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propanoyl)-3-(2-aminoethyl)-2-oxopiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
|
C29H34FN5O3
|
1
|
| 1 |
Ki = 5820 nM
|
|
|
|
CP0234420
|
(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
Show/Hide
|
C36H40ClN5O2S
|
1
|
| 1 |
Ki = 6000 nM
|
|
|
|
CP0432776
|
N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(2,3-dihydro-1H-isoindol-1-yl)acetamide
Show/Hide
|
C35H43ClFN5O2
|
1
|
| 1 |
Ki = 6000 nM
|
|
|
|
CP0386368
|
1-{2-[(1S)-(3-Dimethylaminopropionamino)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
|
C29H40Cl2N4O2
|
1
|
| 1 |
Ki = 6200 nM
|
|
|
|
CP0393003
|
N-[(1R)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-methylpropanoyl]piperazin-1-yl]-6-methylpyridin-3-yl]-3-methylbutyl]-3-(dimethylamino)propanamide
Show/Hide
|
C30H43Cl2N5O2
|
1
|
| 1 |
Ki = 6400 nM
|
|
|
|
CP0382383
|
3-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-1,1-dimethyl-urea
Show/Hide
|
C29H35Cl2N5O2S
|
1
|
| 1 |
Ki = 6800 nM
|
|
|
|
CP0391662
|
N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]pyrrolidine-1-carboxamide
Show/Hide
|
C31H37Cl2N5O2S
|
1
|
| 1 |
Ki = 6900 nM
|
|
|
|
CP0424914
|
N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]isoquinoline-3-carboxamide
Show/Hide
|
C35H39ClFN5O2
|
1
|
| 1 |
Ki = 7000 nM
|
|
|
|
CP0439032
|
N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-1,1-dimethyl-3,4-dihydro-2H-isoquinoline-3-carboxamide
Show/Hide
|
C37H47ClFN5O2
|
1
|
| 1 |
Ki = 7000 nM
|
|
|
|
CP0503293
|
1-{2-[(1S)-(1-Methyl-3-azetadinylcarbonyl)-amino-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
|
C29H38Cl2N4O2
|
1
|
| 1 |
Ki = 8200 nM
|
|
|
|
CP0135976
|
N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-methylphenyl]-3-methylbutyl]-3-(dimethylamino)propanamide
Show/Hide
|
C34H47Cl2N5O3
|
1
|
| 1 |
Ki = 8400 nM
|
|
|
|
CP0500013
|
N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(2-methyl-1,3-dihydroisoindol-1-yl)acetamide
Show/Hide
|
C36H45ClFN5O2
|
1
|
| 1 |
Ki = 8600 nM
|
|
|
|
CP0861958
|
US9040663, 85
Show/Hide
|
C49H67N17O11
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0866052
|
US9040663, 109
Show/Hide
|
C50H68N16O12
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0867773
|
US9040663, 108
Show/Hide
|
C50H69N17O11
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0868834
|
US9040663, 106
Show/Hide
|
C49H67N17O11
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0900315
|
US9040663, 107
Show/Hide
|
C49H66N16O12
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0941547
|
US9040663, 45
Show/Hide
|
C48H67N17O10
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0949179
|
US9040663, 81
Show/Hide
|
C50H70N18O10
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0870730
|
US9447148, 9.46
Show/Hide
|
C32H45N9O7
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
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CP0370229
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-methanesulfonylamino-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
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C30H34ClN5O4S
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1
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| 1 |
Ki = 12000 nM
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CP0455107
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2-[4-[2-Amino-3-(4-fluoro-phenyl)-propionyl]-3-(2-dimethylaminoethyl)-2-oxo-piperazin-1-yl]-N-methyl-3-naphthalen-2-yl-propionamide
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C31H38FN5O3
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1
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| 1 |
Ki = 16832 nM
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CP0424913
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(1-methyl-2,3-dihydroisoindol-1-yl)acetamide
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C36H45ClFN5O2
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1
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| 1 |
Ki = 20000 nM
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CP0460887
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-dimethylaminomethyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
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C32H38ClN5O2
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1
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| 1 |
Ki > 20000 nM
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CP0404967
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(2R)-2-amino-N-[(2R)-5-(diaminomethylideneamino)-1-phenylpentan-2-yl]-3-(4-fluorophenyl)propanamide
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C21H28FN5O
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1
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| 1 |
Ki > 25000 nM
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CP0436210
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Ac-YR[CE(1-Me-H)dFRWC]-NH2
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C61H81N19O13S2
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1
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| 1 |
Ki > 500 nM
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