Brief Information of the Compound and Protein
Compound Name
(2S)-2-((3S)-4-{4-Fluoro-N-[(methyloxy)acetyl]-D-phenylalanyl}-2-oxo-3-propyl-1-piperazinyl)-N-methyl-3-(2-naphthalenyl)propanamide
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PubChem ID
CID: 25132864
SID: 56457344
Canonical SMILES
CCC[C@@H]1N(CCN([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)C1=O)C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)COC
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Compound Formula C33H39FN4O5
Compound Structure
Protein Name
Melanocyte-stimulating hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Melanocortin receptor
Uniprot ID
Q01726
Gene Name
MC1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 308 nM
   TI
   LI
   LO
   TS
2
Ki = 889 nM
   TI
   LI
   LO
   TS