| Compound ID |
Compound Name |
Compound Formula |
|
CP0436766
|
3-[2-(2-aminopyrimidin-5-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C27H27F3N6O
|
1
|
| 1 |
GI50 = 51 nM
|
|
|
|
CP0002211
|
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
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|
C22H27FN4O2
|
1
|
| 1 |
GI50 = 98 nM
|
|
|
|
CP0035428
|
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
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|
C29H27F3N6O
|
1
|
| 1 |
GI50 = 149 nM
|
|
|
|
CP0184069
|
3-[2-(6-amino-5-methylpyridin-3-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C29H30F3N5O
|
1
|
| 1 |
GI50 = 307 nM
|
|
|
|
CP0351447
|
3-[2-(2-aminopyrimidin-5-yl)ethynyl]-2-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C27H27F3N6O
|
1
|
| 1 |
GI50 = 308 nM
|
|
|
|
CP0270974
|
4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(pyridin-3-ylethynyl)benzamide
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|
C28H27F3N4O
|
1
|
| 1 |
GI50 = 333 nM
|
|
|
|
CP0191185
|
3-[2-(6-aminopyridin-3-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C28H28F3N5O
|
1
|
| 1 |
GI50 = 404 nM
|
|
|
|
CP0461776
|
3-[2-(6-aminopyridazin-3-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C27H27F3N6O
|
1
|
| 1 |
GI50 = 459 nM
|
|
|
|
CP0303422
|
3-[2-[2-(2-methoxyethylamino)pyrimidin-5-yl]ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C30H33F3N6O2
|
1
|
| 1 |
GI50 = 481 nM
|
|
|
|
CP0448634
|
3-[2-(3-methoxypyridin-2-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C29H29F3N4O2
|
1
|
| 1 |
GI50 = 564 nM
|
|
|
|
CP0161700
|
4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(2-pyridin-2-ylethynyl)benzamide
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|
C28H27F3N4O
|
1
|
| 1 |
GI50 = 697 nM
|
|
|
|
CP0351448
|
3-(2-imidazo[1,2-a]pyridin-7-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C30H28F3N5O
|
1
|
| 1 |
GI50 = 723 nM
|
|
|
|
CP0538822
|
3-[2-(2-aminopyrimidin-5-yl)ethynyl]-N-[3-fluoro-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-4-methylbenzamide
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|
C26H27FN6O
|
1
|
| 1 |
GI50 = 920 nM
|
|
|
|
CP0184068
|
3-[2-(1-aminoisoquinolin-4-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C32H30F3N5O
|
1
|
| 1 |
GI50 = 926 nM
|
|
|
|
CP0002778
|
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
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|
C29H31N7O
|
1
|
| 1 |
GI50 = 1100 nM
|
|
|
|
CP0161699
|
N-[3-fluoro-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-4-methyl-3-(2-pyridin-3-ylethynyl)benzamide
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|
C27H27FN4O
|
1
|
| 1 |
GI50 = 1639 nM
|
|
|
|
CP0538824
|
4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-(5-phenylmethoxypyridin-2-yl)ethynyl]benzamide
Show/Hide
|
C35H33F3N4O2
|
1
|
| 1 |
GI50 = 2005 nM
|
|
|
|
CP0436767
|
3-[2-(2-aminopyrimidin-5-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]benzamide
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|
C26H28N6O
|
1
|
| 1 |
GI50 = 2063 nM
|
|
|
|
CP0043225
|
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
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|
C21H15ClF4N4O3
|
1
|
| 1 |
GI50 = 3000 nM
|
|
|
|
CP0448635
|
3-iodo-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C21H23F3IN3O
|
1
|
| 1 |
GI50 = 3905 nM
|
|
|
|
CP0531605
|
4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-3-(2-pyridin-3-ylethynyl)benzamide
Show/Hide
|
C27H28N4O
|
1
|
| 1 |
GI50 = 4032 nM
|
|
|
|
CP0191187
|
4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-([1,2,4]triazolo[4,3-a]pyridin-7-yl)ethynyl]benzamide
Show/Hide
|
C29H27F3N6O
|
1
|
| 1 |
GI50 = 4145 nM
|
|
|
|
CP0351449
|
2-ethyl-3-iodo-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C22H25F3IN3O
|
1
|
| 1 |
GI50 = 15858 nM
|
|
|
