Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[2-(3-methoxypyridin-2-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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 PubChem ID
CID: 137653707
Canonical SMILES
COc1cccnc1C#Cc1cc(ccc1C)C(=O)Nc1ccc(CN2CCN(C)CC2)c(c1)C(F)(F)F
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Compound Formula C29H29F3N4O2
Compound Structure
Protein Name
 Protein Info 
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000123 GIST430
 Cell Line Info 
Homo sapiens (Human)  1
1
GI50 = 564 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.7 nM