General Information of the Compound
Compound ID
CP0885348
Compound Name
(3S)-1-bromo-4-((Z)-hexadec-9-enoyloxy)-3-hydroxybutylphosphonic acid
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Structure
Formula
C20H38BrO6P
Molecular Weight
485.396
Canonical SMILES
CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O
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InChI
InChI=1S/C20H38BrO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(23)27-17-18(22)16-19(21)28(24,25)26/h7-8,18-19,22H,2-6,9-17H2,1H3,(H2,24,25,26)/b8-7-/t18-,19?/m0/s1
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InChIKey
ZHWWGWUYVZSXFU-RNTRHVQYSA-N
Physicochemical Property
logP
5.4366
Rotatable Bonds
18
Heavy Atom Count
28
Polar Areas
104.06
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
4
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 122191544
ChEMBL ID
CHEMBL3621964
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03925, Lysophosphatidic acid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000466 McA-RH7777 Rattus norvegicus (Rat)  1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
Protein ID: PT04536, Lysophosphatidic acid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000466 McA-RH7777 Rattus norvegicus (Rat)  1
1
IC50 = 1420 nM
   TI
   LI
   LO
   TS
Protein ID: PT02824, Lysophosphatidic acid receptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000466 McA-RH7777 Rattus norvegicus (Rat)  1
1
IC50 = 1160 nM
   TI
   LI
   LO
   TS
Protein ID: PT05640, Lysophosphatidic acid receptor 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 266 nM
   TI
   LI
   LO
   TS