General Information of the Compound
| Compound ID |
CP0862024
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| Compound Name |
(E)-N-Hydroxy-3-(2-methyl-4-oxo-3-phenyl-3,4-dihydro-quinazolin-8-yl)-acrylamide
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| Structure |
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| Formula |
C18H15N3O3
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| Molecular Weight |
321.336
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| Canonical SMILES |
Cc1nc2c(/C=C/C(=O)NO)cccc2c(=O)n1-c1ccccc1
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| InChI |
InChI=1S/C18H15N3O3/c1-12-19-17-13(10-11-16(22)20-24)6-5-9-15(17)18(23)21(12)14-7-3-2-4-8-14/h2-11,24H,1H3,(H,20,22)/b11-10+
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| InChIKey |
STSNTVHQAOSMDW-ZHACJKMWSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT02410, Histone deacetylase 11
Protein ID: PT00835, Histone deacetylase 2
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8
Protein ID: PT01443, Polyamine deacetylase HDAC10