General Information of the Compound
| Compound ID |
CP0678329
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| Compound Name |
SID49681835
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| Synonyms |
(S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione monohydrochloride
119413-54-6
956S425ZCY
AK-48920
DRG-0288
DSSTox_CID_25952
DSSTox_RID_81248
F S-104864-A
Hycamptamine hydrochloride
NCGC00095189-01
NSC 609699
NSC-609699
NSC609699
Nogitecan hydrochloride
TOPOTECAN HYDROCHLORIDE
Topetecan
Topotecan (Hydrochloride)
Topotecan Hcl
Topotecan hydrochloride [USAN]
Topotecan monohydrochloride
UNII-956S425ZCY
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| Structure |
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| Formula |
C23H24ClN3O5
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| Molecular Weight |
457.914
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| Canonical SMILES |
CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CN(C)C)c(O)ccc3nc2-1.Cl
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| InChI |
InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1
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| InChIKey |
DGHHQBMTXTWTJV-BQAIUKQQSA-N
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| CAS |
119413-54-6
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT06124, Paired box protein Pax-8
Clinical Information about the Compound