General Information of the Compound
Compound ID
CP0465243
Compound Name
(2R,3R)-2-N-[(2S)-2-[(4-tert-butylcyclohexyl)methylamino]pentyl]-1-N,3-dimethylpentane-1,2-diamine
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Structure
Formula
C23H49N3
Molecular Weight
367.666
Canonical SMILES
CCC[C@@H](CN[C@@H](CNC)[C@H](C)CC)NCC1CCC(CC1)C(C)(C)C
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InChI
InChI=1S/C23H49N3/c1-8-10-21(16-26-22(17-24-7)18(3)9-2)25-15-19-11-13-20(14-12-19)23(4,5)6/h18-22,24-26H,8-17H2,1-7H3/t18-,19?,20?,21+,22+/m1/s1
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InChIKey
HRJAFSMLTYZGNF-XGQIVCTBSA-N
Physicochemical Property
logP
4.8209
Rotatable Bonds
12
Heavy Atom Count
26
Polar Areas
36.09
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 24792601
ChEMBL ID
CHEMBL1574585
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
Potency ~ 231.1 nM
   TI
   LI
   LO
   TS
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
Potency ~ 20596.2 nM
   TI
   LI
   LO
   TS
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 14410 nM
   TI
   LI
   LO
   TS