General Information of the Compound
Compound ID
CP0428211
Compound Name
MLS002248660
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Structure
Formula
C16H17N3O6S2
Molecular Weight
411.461
Canonical SMILES
Cc1ccc(NC(=O)c2ccc(s2)[N+]([O-])=O)cc1S(=O)(=O)N1CCOCC1
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InChI
InChI=1S/C16H17N3O6S2/c1-11-2-3-12(17-16(20)13-4-5-15(26-13)19(21)22)10-14(11)27(23,24)18-6-8-25-9-7-18/h2-5,10H,6-9H2,1H3,(H,17,20)
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InChIKey
IYOYRXNSHLXJBV-UHFFFAOYSA-N
Physicochemical Property
logP
2.23792
Rotatable Bonds
5
Heavy Atom Count
27
Polar Areas
118.85
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 4791406
ChEMBL ID
CHEMBL1730515
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
Potency ~ 29092.9 nM
   TI
   LI
   LO
   TS
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
Potency ~ 18356.4 nM
   TI
   LI
   LO
   TS
Protein ID: PT06033, Microphthalmia-associated transcription factor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000242 SK-MEL-5 Homo sapiens (Human)  1
1
AC50 = 16190 nM
   TI
   LI
   LO
   TS
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 3940 nM
   TI
   LI
   LO
   TS