General Information of the Compound
| Compound ID |
CP0417344
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| Compound Name |
5-tosyl-5H-dibenzo[b,d]azepin-7(6H)-one
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| Synonyms |
24127-35-3
5,6-dihydro-5-(p-tolylsulfonyl)-7h-dibenz[b,d]azepin-7-one
5-(4-methylphenyl)sulfonyl-6H-benzo[d][1]benzazepin-7-one
5-(Toluene-4-sulfonyl)-5,6-dihydro-dibenzo[b,d]azepin-7-one
5-[(4-Methylphenyl)sulfonyl]-5,6-dihydro-7H-dibenzo[b,d]azepin-7-one #
5-tosyl-5H-dibenzo[b,d]azepin-7(6H)-one
7H-Dibenz[b,d]azepin-7-one, 5,6-dihydro-5-(p-tolylsulfonyl)-
AC1LCKZQ
BDBM50279063
CHEMBL498086
CTK8H7702
HMS1547N18
KB-310270
KCIOJLFKVQHRPU-UHFFFAOYSA-N
Oprea1_188679
SCHEMBL3034555
TimTec1_004880
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| Structure |
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| Formula |
C21H17NO3S
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| Molecular Weight |
363.438
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| Canonical SMILES |
Cc1ccc(cc1)S(=O)(=O)N1CC(=O)c2ccccc2-c2ccccc12
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| InChI |
InChI=1S/C21H17NO3S/c1-15-10-12-16(13-11-15)26(24,25)22-14-21(23)19-8-3-2-6-17(19)18-7-4-5-9-20(18)22/h2-13H,14H2,1H3
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| InChIKey |
KCIOJLFKVQHRPU-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00984, Intermediate conductance calcium-activated potassium channel protein 4
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000150 | HaCaT | Homo sapiens (Human) | 1 |
| 1 |
EC50 = 8400 nM
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LI
LO
TS
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| CL000752 | PBMC iPSC #1 | Homo sapiens (Human) | 1 |
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EC50 = 2500 nM
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TI
LI
LO
TS
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Clinical Information about the Compound
Drug 1 ( 5-tosyl-5H-dibenzo[b,d]azepin-7(6H)-one )
| Drug Name | 5-tosyl-5H-dibenzo[b,d]azepin-7(6H)-one | ||
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