General Information of the Compound
Compound ID
CP0176463
Compound Name
2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]methyl]-4,5-bis(chloranyl)pyridazin-3-one
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Structure
Formula
C13H7BrCl2N4O2
Molecular Weight
402.035
Canonical SMILES
Clc1cnn(Cc2nnc(o2)-c2ccccc2Br)c(=O)c1Cl
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InChI
InChI=1S/C13H7BrCl2N4O2/c14-8-4-2-1-3-7(8)12-19-18-10(22-12)6-20-13(21)11(16)9(15)5-17-20/h1-5H,6H2
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InChIKey
JZBXRUCPXQISGH-UHFFFAOYSA-N
Physicochemical Property
logP
3.4109
Rotatable Bonds
3
Heavy Atom Count
22
Polar Areas
73.81
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 2530952
ChEMBL ID
CHEMBL1319618
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
Potency ~ 4610.9 nM
   TI
   LI
   LO
   TS
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
Potency ~ 11582.1 nM
   TI
   LI
   LO
   TS
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 7630 nM
   TI
   LI
   LO
   TS