General Information of the Compound
| Compound ID |
CP0127298
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
US9428503, 1
Show/Hide
|
||||||||||||||||||
| Synonyms |
1821428-35-6
8-(6-(3-(dimethylamino)propoxy)pyridin-3-yl)-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[
8-[6-[3-(dimethylamino)propoxy]pyridin-3-yl]-3-methyl-1-(oxan-4-yl)imidazo[4,5-c]quinolin-2-one
AKOS030629510
AOTRIQLYUAFVSC-UHFFFAOYSA-N
AS-35329
AZD 0156 [WHO-DD]
AZD-0156
AZD0156
AZD0156 (AZD-0156)
BCP18990
BDBM245474
CHEMBL3960662
CS-5889
EX-A1321
GTPL9942
HY-100016
MolPort-044-560-374
P5T0XWC07Z
SB19769
SCHEMBL17246146
UNII-P5T0XWC07Z
US9428503, 1
ZINC498035578
compound 64 [PMID: 29683659]
s8375
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C26H31N5O3
|
||||||||||||||||||
| Molecular Weight |
461.566
|
||||||||||||||||||
| Canonical SMILES |
CN(C)CCCOc1ccc(cn1)-c1ccc2ncc3n(C)c(=O)n(C4CCOCC4)c3c2c1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C26H31N5O3/c1-29(2)11-4-12-34-24-8-6-19(16-28-24)18-5-7-22-21(15-18)25-23(17-27-22)30(3)26(32)31(25)20-9-13-33-14-10-20/h5-8,15-17,20H,4,9-14H2,1-3H3
Show/Hide
|
||||||||||||||||||
| InChIKey |
AOTRIQLYUAFVSC-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01902, Serine-protein kinase ATM
Protein ID: PT01934, Serine/threonine-protein kinase ATR
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Clinical Information about the Compound