General Information of the Compound
| Compound ID |
CP0117225
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| Compound Name |
5-hydroxy-1,4-dihydronaphthalene-1,4-dione
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| Synonyms |
1,4-NAPHTHALENEDIONE, 5-HYDROXY-
1,4-Naphthoquinone, 5-hydroxy-
1,4-Naphthoquinone, 8-hydroxy-
481-39-0
5-Hydroxy-1,4-naftochinon
5-Hydroxy-1,4-naphthalenedione
5-Hydroxy-1,4-naphthoquinone
5-Hydroxy-1,4-naphthosemiquinone
5-Hydroxy-p-naphthoquinone
5-Hydroxynaphthalene-1,4-dione
5-Hydroxynaphthoquinone
8-Hydroxy-1,4-naphthoquinone
Akhnot
Avastin+/-Tarceva
CCRIS
CI 75500
CI Natural Brown 7
Caswell No 515AA
Iuglon
JUGLONE
Juglane
Juglon
Juglone
Jugnlon
NSC 153189
NSC 622948
Nucin
Regianin
UNII-W6Q80SK9L6
Walnut extract
Yuglon
juglone
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| Structure |
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| Formula |
C10H6O3
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| Molecular Weight |
174.155
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| Canonical SMILES |
Oc1cccc2C(=O)C=CC(=O)c12
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| InChI |
InChI=1S/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12H
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| InChIKey |
KQPYUDDGWXQXHS-UHFFFAOYSA-N
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| CAS |
481-39-0
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound
Drug 1 ( Avastin+/-Tarceva )
| Drug Name | Avastin+/-Tarceva | ||
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| Company | Genentech | ||
| Indication | |||
| Target(s) |
Vascular endothelial growth factor A (VEGFA)
Inhibitor
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