General Information of the Protein
| Protein ID |
PT06969
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| Protein Name |
Dual specificity protein phosphatase 1
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| Secondarily Protein Name |
Mitogen-activated protein kinase phosphatase 1
Protein-tyrosine phosphatase 3CH134
Protein-tyrosine phosphatase ERP
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| Gene Name |
DUSP1
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| Secondarily Gene Name |
3ch134
Mkp1
Ptpn10
Ptpn16
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| Sequence |
MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLKSPITTSPSC
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| Organism |
Mus musculus, Mouse
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| Protein Classification |
Enzyme
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Phosphatase
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Protein Phosphatase
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Serine/threonine/tyrosine protein phosphatase
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| Function |
Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
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| Uniprot ID | |||||
| Subcellular Location |
Nucleus
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000017 , HeLa
