General Information of the Protein
| Protein ID |
PT03872
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| Protein Name |
Dual specificity protein phosphatase 1
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| Secondarily Protein Name |
Dual specificity protein phosphatase hVH1
Mitogen-activated protein kinase phosphatase 1
Protein-tyrosine phosphatase CL100
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| Gene Name |
DUSP1
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| Secondarily Gene Name |
CL100
MKP1
PTPN10
VH1
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| Sequence |
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC
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| Organism |
Homo sapiens, Human
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| Protein Classification |
Enzyme
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Phosphatase
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Protein Phosphatase
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Serine/threonine/tyrosine protein phosphatase
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| Function |
Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
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| Uniprot ID |
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| HGNC ID | |||||
| Subcellular Location |
Nucleus
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Clinical Information about the Protein