General Information of the Compound
| Compound ID |
CP0062733
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| Compound Name |
3beta-O-Succinyl-18-beta-glycyrrhetinic acid
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| Synonyms |
(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-(4-hydroxy-4-oxobutanoyl)oxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
3beta-(3-Carboxypropionyloxy)-11-oxo-olean-12-en-30-saeure
3beta-Hydroxy-11-oxoolean-12-en-30-saeure hydogensuccinat
5697-56-3
CBO
Carbenoxolona
Carbenoxolona [INN-Spanish]
Carbenoxolone
Carbenoxolone [INN:BAN]
Carbenoxolonum
Carbenoxolonum [INN-Latin]
EINECS 227-174-2
MM6384NG73
OBZHEBDUNPOCJG-WBXJDKIVSA-N
UNII-MM6384NG73
carbenoxolone
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| Structure |
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| Formula |
C34H50O7
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| Molecular Weight |
570.767
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| Canonical SMILES |
CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)OC(=O)CCC(O)=O
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| InChI |
InChI=1S/C34H50O7/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40)/t21-,23-,24-,27+,30+,31-,32-,33+,34+/m0/s1
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| InChIKey |
OBZHEBDUNPOCJG-WBXJDKIVSA-N
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| CAS |
5697-56-3
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01109, 11-beta-hydroxysteroid dehydrogenase 1
Protein ID: PT01107, 11-beta-hydroxysteroid dehydrogenase 1
Protein ID: PT01111, 11-beta-hydroxysteroid dehydrogenase type 2
Clinical Information about the Compound
Drug 1 ( Carbenoxolone )
| Drug Name | Carbenoxolone | ||
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| Target(s) |
Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1)
Inhibitor
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