Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

3beta-O-Succinyl-18-beta-glycyrrhetinic acid

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PubChem ID

CID: 636403

SID: 16767811

Canonical SMILES	CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)OC(=O)CCC(O)=O Show/Hide
Compound Formula	C34H50O7

Compound Structure

Protein Name

Protein Info

11-beta-hydroxysteroid dehydrogenase 1

Protein Classification

Enzyme

Oxidoreductase

Uniprot ID

P28845

Gene Name

HSD11B1

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	1
1	IC50 = 500 nM	TI LI LO TS
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	IC50 = 500 nM	TI LI LO TS
2	IC50 = 1630 nM	TI LI LO TS

Biochemical Assays