General Information of the Compound
| Compound ID |
CP0053630
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| Compound Name |
2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid
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| Synonyms |
2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine
2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazine
2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine
2-Chloro-10-[3-(4-methyl-1-piper-azinyl)propyl]-10H-pheno-thiazine dimaleate
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine
3-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine
6140 RP
Bayer A 173
Buccastem (TN)
CHLOPERAZINE
Capazine
Chlormeprazine
Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine
Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French]
Chlorperazine
Combid
Compazine
Compazine (*Maleate*)
Compazine (TN)
Compazine Suppositories
Compro
Compro (TN)
Emelent
Eskatrol
Kronocin
Meterazin
Meterazine
N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine
Nipodal
Novamin
P77
Phenotil (TN)
Prochloroperazine
Prochlorpemazine
Prochlorperazin
Prochlorperazine
Prochlorperazine (JAN/USP/INN)
Prochlorperazine Edisylate Salt
Prochlorperazine [USAN:INN:BAN:JAN]
Prochlorperazine dihydrobromide
Prochlorperazine dimaleate
Prochlorperazine maleate
Prochlorperazine mesilate
Prochlorperazinum
Prochlorperazinum [INN-Latin]
Prochlorpermazine
Prochlorpromazine
Procloperazine
Proclorperazina
Proclorperazina [INN-Spanish]
Proclorperazine
RP 6140
SKF 4657
Stemetil
Stemetil (TN)
Stemzine (TN)
Tementil
Temetid
Vertigon
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| Structure |
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| Formula |
C20H24ClN3S
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| Molecular Weight |
373.953
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| Canonical SMILES |
CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1
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| InChI |
InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3
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| InChIKey |
WIKYUJGCLQQFNW-UHFFFAOYSA-N
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| CAS |
58-38-8
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01002, Cytochrome P450 1A2
Protein ID: PT00817, Cytochrome P450 2D6
Protein ID: PT06109, Geminin
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Protein ID: PT03795, Solute carrier family 22 member 1
Clinical Information about the Compound