General Information of the Compound
| Compound ID |
CP0042374
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| Compound Name |
(11beta)-11,21-dihydroxypregn-4-ene-3,20-dione
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| Synonyms |
(11-BETA)-11,21-DIHYDROXY-PREGN-4-ENE-3,20-DIONE
(11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione
11,12-Dihydroxyprogesterone
11,21-Dihydroxyprogesterone
11-Hydroxycorticoaldosterone
11-beta,21-Dihydroxypregn-3,20-dione
11Beta,21-dihydroxypregn-4-ene-3,20-dione
11beta,21-Dihydroxy-4-pregnene-3,20-dione
11beta,21-Dihydroxyprogesterone
17-Deoxycortisol
4-Pregnene-11beta,21-diol-3,20-dione
50-22-6
CCRIS 6753
CHEBI:16827
CORTICOSTERONE
Compound B
Corticosteron
Corticosterone
Kendall's compound B
NSC9705
Reichstein's B
Reichstein's substance H
UNII-W980KJ009P
corticosterone
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| Structure |
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| Formula |
C21H30O4
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| Molecular Weight |
346.467
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| Canonical SMILES |
C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO
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| InChI |
InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
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| InChIKey |
OMFXVFTZEKFJBZ-HJTSIMOOSA-N
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| CAS |
50-22-6
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Protein ID: PT03795, Solute carrier family 22 member 1
Protein ID: PT06157, Solute carrier family 22 member 1
Protein ID: PT04591, Solute carrier family 22 member 2
Protein ID: PT04368, Solute carrier family 22 member 2
Protein ID: PT06607, Solute carrier family 22 member 3
Protein ID: PT06135, Solute carrier organic anion transporter family member 1A1
Clinical Information about the Compound