General Information of the Compound
| Compound ID |
CP0036865
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| Compound Name |
Atripla
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| Synonyms |
(R)-9-(2-Phosphonomethoxypropyl)adenine
(R)-9-(2-Phosphonylmethoxypropyl)adenine
(R)-PMPA
Apropovir
D,L-Tenofovir
GNA & Tenofovir
GS 1275
GS 1278
GS1278
HHA & Tenofovir
KS-5021
PMPA
PMPA-(R)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-& Galanthus nivalis agglutinin (GNA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-& Hippeastrum hybrid agglutinin(HHA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-(9CI)
Phosphonic acid, [[2-(6-amino-9H-purin-9
TFV
Tenefovir
Tenofovir
Viread (TN)
Viread, Tenofovir
[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
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| Structure |
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| Formula |
C9H14N5O4P
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| Molecular Weight |
287.216
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| Canonical SMILES |
C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(O)=O
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| InChI |
InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1
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| InChIKey |
SGOIRFVFHAKUTI-ZCFIWIBFSA-N
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| CAS |
147127-20-6
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00295, Capsid protein
Protein ID: PT00005, Reverse transcriptase/RNaseH
Cell Viability or Cytotoxicity Assay
Clinical Information about the Compound