General Information of the Compound
| Compound ID |
CP0016685
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| Compound Name |
3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
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| Synonyms |
1H-Pyrrole-2,5-dione, 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-
280744-09-4
3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione
AC1L41YI
AOB5004
BDBM8296
CHEBI:91421
CHEMBL102714
CTK8B4807
EX-A291
GTPL8015
Lopac-S-3442
Lopac0_000934
MLS001074894
SB 216763
SB-216763
SB216763
SCHEMBL30251
SR-01000076052
SYN1075
Tocris-1616
cid_176158
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| Structure |
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| Formula |
C19H12Cl2N2O2
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| Molecular Weight |
371.223
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| Canonical SMILES |
Cn1cc(C2=C(C(=O)NC2=O)c2ccc(Cl)cc2Cl)c2ccccc12
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| InChI |
InChI=1S/C19H12Cl2N2O2/c1-23-9-13(11-4-2-3-5-15(11)23)17-16(18(24)22-19(17)25)12-7-6-10(20)8-14(12)21/h2-9H,1H3,(H,22,24,25)
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| InChIKey |
JCSGFHVFHSKIJH-UHFFFAOYSA-N
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| CAS |
280744-09-4
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Protein ID: PT00962, Glycogen synthase kinase-3 beta
Protein ID: PT06124, Paired box protein Pax-8
Clinical Information about the Compound
Drug 1 ( SB216763 )
| Drug Name | SB216763 | ||
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| Target(s) |
Glycogen synthase kinase-3 alpha (GSK-3A)
Inhibitor
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