Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
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 PubChem ID
CID: 176158
SID: 14804046
Canonical SMILES
Cn1cc(C2=C(C(=O)NC2=O)c2ccc(Cl)cc2Cl)c2ccccc12
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Compound Formula C19H12Cl2N2O2
Compound Structure
Protein Name
 Protein Info 
Glycogen synthase kinase-3 beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase GSK family
Uniprot ID
P49841
Gene Name
GSK3B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 19.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 20 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 33.88 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM
2 IC50 = 8.35 nM
3 IC50 = 9 nM
4 IC50 = 11.4 nM
5 IC50 = 34 nM
6 IC50 = 48 nM
7 IC50 = 50 nM
8 IC50 = 89 nM
9 IC50 = 92 nM